Home DNA Damage/DNA Repair DNA/RNA Synthesis inhibitor - Autophagy activator - Apoptosis related activator - Nucleoside Analog/Antimetabolite inhibitor Cytarabine For research use only.

Cytarabine

Synonyms: Cytarabin,Ara-C,Arabinofuranosyl Cytidine,Cytosine β-D-arabinofuranoside,Cytosine arabinoside,NSC 63878,NSC 287459,U-19920A

Cytarabine is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells. Cytarabine induces autophagy and apoptosis.

Cytarabine Chemical Structure

Cytarabine Chemical Structure

CAS No. 147-94-4

Purity & Quality Control

Cytarabine Related Products

Signaling Pathway

DNA/RNA Synthesis Signaling Pathways

DNA/RNA Synthesis Signaling Pathway

Cell Data

Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
murine leukemia P388 Function assay Anticancer activity carried out in vitro against murine leukemia P388, IC50=0.14 μM 11356110
L1210 cell lines Function assay Concentration required to inhibit replication of L1210 cell lines by 50% after 72 hr incubation, ED50=0.05 μM. 1652024
CCRF-CEM cell lines Function assay 72 h Concentration required to inhibit replication of CCRF-CEM cell lines by 50% after 72 hr incubation, ED50=6 nM. 1652024
CCRF-CEM cell line Function assay Inhibit the replication of CCRF-CEM cell line in vitro, ED50=5 nM. 1995894
HeLa human cell lines Function assay 144 h The compound was tested in vitro for antitumor activity(50% inhibition of tumor cell growth) against HeLa human cell lines after 144 hr, ID50=0.1 μM 3625714
L1210 murine cell lines Function assay 72 h The compound was tested in vitro for antitumor activity(50% inhibition of tumor cell growth) against the L1210 murine cell lines after 72 hours, ID50=20 nM. 3625714
P388 murine cell lines Function assay 72 h The compound was tested in vitro for antitumor activity(50% inhibition of tumor cell growth) against the P388 murine cell lines after 72 hours, ID50=20 nM. 3625714
RPMI-6410 human leukemic lymphoblastoid cell lines Cytotoxic assay Cytotoxicity against RPMI-6410 human leukemic lymphoblastoid cell lines, IC50=0.06 μM 6827546
CCRF-CEM human leukemic lymphoblastoid cell lines Cytotoxic assay Cytotoxicity against CCRF-CEM human leukemic lymphoblastoid cell lines, IC50=20 nM. 6827546
MOLT-4 human leukemic lymphoblastoid cell lines Cytotoxic assay Cytotoxicity against MOLT-4 human leukemic lymphoblastoid cell lines, IC50=10 nM. 6827546
human leukemia cell line(CCRF-CEM) Cytotoxic assay In vitro cytotoxicity of compounds were determined on Inhibition of human leukemia cell line(CCRF-CEM), IC50=0.09 μM. 8917645
HL60 Function assay In vitro concentration required to induce apoptosis in HL60 cells, AC50 = 0.15 μM. 12877593
HL60R Function assay In vitro concentration required to induce apoptosis in HL60R cells, AC50 = 8 μM. 12877593
CCRF-CEM Cytotoxicity assay 48 hrs Cytotoxicity against human CCRF-CEM cells after 48 hrs by cell titer-blue assay, EC50 = 0.005614 μM. 19743858
CCRF-CEM/C2 Cytotoxicity assay 48 hrs Cytotoxicity against human CCRF-CEM/C2 cells after 48 hrs by cell titer-blue assay, EC50 = 0.0228 μM. 19743858
HL60/MX2 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60/MX2 cells after 48 hrs by cell titer-blue assay, EC50 = 0.2612 μM. 19743858
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by cell titer-blue assay, EC50 = 0.6572 μM. 19743858
L1210 Cytotoxicity assay 72 hrs Cytotoxicity against mouse L1210 cells assessed as growth inhibition measured at 72 hrs by trypan blue exclusion assay, ED50 = 0.1 μM. 118258
BGM Antiviral assay 5 days Antiviral activity against Vaccinia virus IHD infected in African green monkey BGM cells assessed as plaque reduction measured on day 5 by disk diffusion assay, ED50 = 0.07 μM. 178873
BGM Antiviral assay 5 days Antiviral activity against Herpes Simplex virus HF infected in African green monkey BGM cells assessed as plaque reduction measured on day 5 by disk diffusion assay, ED50 = 0.16 μM. 178873
L1210 Function assay Inhibition of thymidylate synthase in L1210 cells, ED50 = 0.03 μM. 3027329
BALL-1 Growth inhibition assay 24 hrs Growth inhibition of human BALL-1 cells after 24 hrs by WST-1 assay, GI50 = 0.08 μM. 22264170
HCT116 Growth inhibition assay 24 hrs Growth inhibition of against human HCT116 cells after 24 hrs by WST-1 assay, GI50 = 0.12 μM. 22264170
HeLa Growth inhibition assay 24 hrs Growth inhibition of human HeLa cells after 24 hrs by WST-1 assay, GI50 = 0.18 μM. 22264170
A549 Growth inhibition assay 24 hrs Growth inhibition of human A549 cells after 24 hrs by WST-1 assay, GI50 = 0.2 μM. 22264170
HUVEC Growth inhibition assay 72 hrs Growth inhibition of HUVEC cells after 72 hrs by WST-1 assay, GI50 = 0.23 μM. 22264170
NUGC3 Growth inhibition assay 24 hrs Growth inhibition of human NUGC3 cells after 24 hrs by WST-1 assay, GI50 = 0.25 μM. 22264170
HDF Growth inhibition assay 72 hrs Growth inhibition of HDF cells after 72 hrs by WST-1 assay, GI50 = 0.25 μM. 22264170
leukemia L1210 Function assay Inhibition of L1210 lymphoid leukemia cells 48 hr after administration (length of preincubation=0 hr), IC50 = 0.01 μM. 1527783
leukemia L1210 Function assay Inhibition of L1210 lymphoid leukemia cells 72 hr after administration (length of preincubation=0 hr), IC50 = 0.01 μM. 1527783
leukemia L1210 Function assay Inhibition of L1210 lymphoid leukemia cells 24 hr after administration (length of preincubation=0 hr), IC50 = 0.1 μM. 1527783
leukemia L1210 Function assay Inhibitory concentration on multidrug-resistant L1210 leukemia cells., IC50 = 0.036 μM. 1906107
leukemia L1210 Function assay Inhibitory concentration on parentral (sensitive) L1210 leukemia cells., IC50 = 0.036 μM. 1906107
leukemia L1210 Function assay Inhibitory activity against murine leukemia L1210 cells, IC50 = 0.08 μM. 1992143
HT-29 Antiproliferative assay 96 hrs Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay, IC50 = 0.066 μM. 2778449
P388 Antiproliferative assay 48 hrs Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay, IC50 = 1.233 μM. 2778449
KB Function assay Tested in vitro inhibitory activity against human oral epidermoid carcinoma KB cells, IC50 = 2.3 μM. 8277499
K562(S) Growth inhibition assay Inhibition of cell growth against human myeloid leukemia K562(S) cells, IC50 = 0.5 μM. 10560743
NCI-H23 Cytotoxicity assay In vitro cytotoxicity was evaluated against lung NCI-H23 cells; 1 x 10E1, IC50 = 1 μM. 10780904
SNB-7 Cytotoxicity assay In vitro cytotoxicity was evaluated againstCNS SNB-7 cells; 1 x 10E1, IC50 = 1 μM. 10780904
SK-MEL-28 Cytotoxicity assay In vitro cytotoxicity was evaluated against melanoma SK-MEL-28 cells, IC50 = 1 μM. 10780904
HL60 Function assay In vitro inhibitory concentration against proliferation of HL60 cells, IC50 = 0.08 μM. 12877593
HL60R Function assay In vitro concentration required to induce apoptosis in HL60R cells, IC50 = 0.35 μM. 12877593
CCRF-HSB-2 Growth inhibition assay Growth inhibition of human CCRF-HSB-2 cells by MTT assay, IC50 = 0.15 μM. 17049252
KB Growth inhibition assay Growth inhibition of human KB cells by MTT assay, IC50 = 0.7 μM. 17049252
L1210/0 Cytotoxicity assay 48 hrs Cytotoxicity against mouse L1210/0 cells after 48 hrs, IC50 = 0.7 μM. 17341060
2209-23 Antiviral assay Antiviral activity against Hepatitis C virus infected human 2209-23 cells by genotype 1b replicon assay, IC50 = 0.02 μM. 19055482
2209-23 Antiproliferative assay Antiproliferative activity against human 2209-23 cells by [3H]thymidine incorporation scintillation proximity assay, IC50 = 0.029 μM. 19055482
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.118 μM. 19321234
SF268 Cytotoxicity assay Cytotoxicity against human SF268 cells by MTT assay, IC50 = 0.00768 μM. 19345581
L1210 Cytotoxicity assay 3 days Cytotoxicity against deoxynucleoside analogue-sensitive mouse L1210 cells after 3 days by MTT assay, IC50 = 0.0004 μM. 19674903
CCRF-CEM Cytotoxicity assay 3 days Cytotoxicity against deoxynucleoside analogue-sensitive human CCRF-CEM cells after 3 days by MTT assay, IC50 = 0.001 μM. 19674903
MCF7 Cytotoxicity assay 3 days Cytotoxicity against deoxynucleoside analogue-sensitive human MCF7 cells after 3 days by MTT assay, IC50 = 0.004 μM. 19674903
MCF7 1K Cytotoxicity assay 3 days Cytotoxicity against deoxynucleoside analogue-resistant human MCF7 1K cells overexpressing ribonucleotide reductase after 3 days by MTT assay, IC50 = 0.04 μM. 19674903
MESSA Cytotoxicity assay 3 days Cytotoxicity against deoxynucleoside analogue-sensitive human MESSA cells after 3 days by MTT assay, IC50 = 1.7 μM. 19674903
K562 Cytotoxicity assay Cytotoxicity against human K562 cells by sulforhodamine B method, IC50 = 0.05 μM. 19691349
SNU638 Cytotoxicity assay Cytotoxicity against human SNU638 cells by sulforhodamine B method, IC50 = 0.15 μM. 19691349
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by sulforhodamine B method, IC50 = 1.9 μM. 19691349
T47D Cytotoxicity assay Cytotoxicity against human T47D cells by sulforhodamine B method, IC50 = 2.7 μM. 19691349
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells by sulforhodamine B method, IC50 = 5.3 μM. 19691349
L1210 Cytotoxicity assay 2 days Cytotoxicity against mouse L1210 cells after 2 days, IC50 = 0.024 μM. 19910080
CEM Cytotoxicity assay 2 days Cytotoxicity against human CEM cells after 2 days, IC50 = 0.024 μM. 19910080
CEM Cytotoxicity assay 48 hrs Cytotoxicity against human CEM cells assessed as inhibition of cell proliferation after 48 hrs, IC50 = 0.024 μM. 20000418
L1210 Cytotoxicity assay 48 hrs Cytotoxicity against mouse L1210 cells assessed as inhibition of cell proliferation after 48 hrs, IC50 = 0.024 μM. 20000418
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs, IC50 = 0.26 μM. 20000418
RS4:11 Antiproliferative assay 72 hrs Antiproliferative activity against human RS4:11 cells having FLT3-ITD mutation after 72 hrs by WST8 assay, IC50 = 0.26 μM. 20153646
MV411 Antiproliferative assay 72 hrs Antiproliferative activity against wild type FLT3 expressing human MV411 cells after 72 hrs by WST8 assay, IC50 = 3.36 μM. 20153646
HCT116 Antitumor assay 24 hrs Antitumor activity against human HCT116 cells after 24 hrs by MTT assay, IC50 = 0.1 μM. 20211564
H460 Antitumor assay 24 hrs Antitumor activity against human H460 cells after 24 hrs by MTT assay, IC50 = 0.1 μM. 20211564
MOLT4 Antitumor assay 24 hrs Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay, IC50 = 1 μM. 20211564
SW620 Antitumor assay 24 hrs Antitumor activity against human SW620 cells after 24 hrs by MTT assay, IC50 = 30 μM. 20211564
SF268 Cytotoxicity assay 3 days Cytotoxicity against human SF268 cells after 3 days by MTT assay, IC50 = 7.68 μM. 20356655
SFME Antiproliferative assay 24 hrs Antiproliferative activity against mouse SFME cells after 24 hrs by MTT assay, IC50 = 0.8 μM. 20398972
HM-SFME-1 Antiproliferative assay 24 hrs Antiproliferative activity against mouse r/m HM-SFME-1 cells after 24 hrs by MTT assay, IC50 = 33.3 μM. 20398972
HepG2 Cytotoxicity assay 24 hrs Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay, IC50 = 0.2 μM. 20692841
K562 Cytotoxicity assay 24 hrs Cytotoxicity against human K562 cells after 24 hrs by MTT assay, IC50 = 33.5 μM. 20692841
Bel7402 Cytotoxicity assay 24 hrs Cytotoxicity against human Bel7402 cells after 24 hrs by MTT assay, IC50 = 34.2 μM. 20692841
K562 Antiproliferative assay 48 hrs Antiproliferative activity against human K562 cells after 48 hrs by MTT assay, IC50 = 24.29 μM. 21620529
S180 Antiproliferative assay 48 hrs Antiproliferative activity against mouse S180 cells after 48 hrs by MTT assay, IC50 = 25.43 μM. 21620529
H22 Antiproliferative assay 48 hrs Antiproliferative activity against mouse H22 cells after 48 hrs by MTT assay, IC50 = 25.98 μM. 21620529
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 26.23 μM. 21620529
B16 Antiproliferative assay 48 hrs Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay, IC50 = 30.62 μM. 21620529
CCRF-CEM Cytotoxicity assay 48 hrs Cytotoxicity against human CCRF-CEM cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50 = 0.006 μM. 22582991
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50 = 0.049 μM. 22582991
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50 = 14 μM. 22582991
blood stem/progenitor cells Cytotoxicity assay 48 hrs Cytotoxicity against human CD34-positive blood stem/progenitor cells after 48 hrs by MTT assay, IC50 = 0.59 μM. 23578690
MA9.3 Cytotoxicity assay 48 hrs Cytotoxicity against human MA9.3 cells after 48 hrs by MTT assay, IC50 = 0.92 μM. 23578690
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by SRB assay, IC50 = 3.54 μM. 23867603
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay, IC50 = 3.82 μM. 23867603
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 4.07 μM. 23867603
K562 Cytotoxicity assay Cytotoxicity against human K562 cells by SRB assay, IC50 = 0.05 μM. 24956556
SNU638 Cytotoxicity assay Cytotoxicity against human SNU638 cells by SRB assay, IC50 = 0.15 μM. 24956556
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by SRB assay, IC50 = 1.9 μM. 24956556
T47D Cytotoxicity assay Cytotoxicity against human T47D cells by SRB assay, IC50 = 2.72 μM. 24956556
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells by SRB assay, IC50 = 5.3 μM. 24956556
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 1.2 μM. 26010585
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 1.37 μM. 26010585
SKHEP1 Cytotoxicity assay 72 hrs Cytotoxicity against human SKHEP1 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 2.12 μM. 26010585
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 2.42 μM. 26010585
SNU638 Cytotoxicity assay 72 hrs Cytotoxicity against human SNU638 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 3.98 μM. 26010585
143B Cytotoxicity assay 72 hrs Cytotoxicity against human 143B cells after 72 hrs by SRB assay, IC50 = 2.06 μM. 27073055
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay, IC50 = 2.86 μM. 27073055
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by SRB assay, IC50 = 3.54 μM. 27073055
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7cells after 72 hrs by SRB assay, IC50 = 3.82 μM. 27073055
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 4.07 μM. 27073055
HDF Cytotoxicity assay 72 hrs Cytotoxicity against HDF cells after 72 hrs by SRB assay, IC50 = 4.99 μM. 27073055
thymidine kinase deficient 143B Cytotoxicity assay 72 hrs Cytotoxicity against human thymidine kinase deficient 143B cells after 72 hrs by SRB assay, IC50 = 16.88 μM. 27073055
SMMC7721 Cytotoxicity assay 72 hrs Cytotoxicity against human SMMC7721 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 0.013 μM. 29886320
LO2 Cytotoxicity assay 72 hrs Cytotoxicity against human LO2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 0.17 μM. 29886320
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells, IC50 = 0.95 μM. 29886320
SNU638 Cytotoxicity assay 72 hrs Cytotoxicity against human SNU638 cells assessed as decrease in cell viability after 72 hrs by SRB assay, IC50 = 1.08 μM. 29906687
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by SRB assay, IC50 = 1.75 μM. 29906687
SKHEP1 Cytotoxicity assay 72 hrs Cytotoxicity against human SKHEP1 cells assessed as decrease in cell viability after 72 hrs by SRB assay, IC50 = 1.8 μM. 29906687
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 72 hrs by SRB assay, IC50 = 4.4 μM. 29906687
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 72 hrs by SRB assay, IC50 = 10.49 μM. 29906687
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 72 hrs by SRB assay, IC50 = 48.4 μM. 29906687
Jurkat E6-1 Antiproliferative assay Antiproliferative activity against human Jurkat E6-1 cells, IC50 = 0.018 μM. 30114661
HL60 Antiproliferative assay Antiproliferative activity against human HL60 cells, IC50 = 0.185 μM. 30114661
BL21(DE3) Function assay 3 mins Activity of human recombinant N-terminal His-tagged DCK Pro122Ser mutant expressed in Escherichia coli BL21(DE3) cells assessed as cytosine-beta-D-arabinofuranoside-5'-MP formation incubated for 3 mins by liquid chromatography-tandem mass spectrometry, Km = 1.56 μM. 23230131
BL21(DE3) Function assay 3 mins Activity of human recombinant N-terminal His-tagged DCK Ile24Val mutant expressed in Escherichia coli BL21(DE3) cells assessed as cytosine-beta-D-arabinofuranoside-5'-MP formation incubated for 3 mins by liquid chromatography-tandem mass spectrometry, Km = 2.45 μM. 23230131
BL21(DE3) Function assay 3 mins Activity of human recombinant N-terminal His-tagged DCK Ala119Gly mutant expressed in Escherichia coli BL21(DE3) cells assessed as cytosine-beta-D-arabinofuranoside-5'-MP formation incubated for 3 mins by liquid chromatography-tandem mass spectrometry, Km = 2.54 μM. 23230131
BL21(DE3) Function assay 3 mins Activity of human recombinant N-terminal His-tagged wild type DCK expressed in Escherichia coli BL21(DE3) cells assessed as cytosine-beta-D-arabinofuranoside-5'-MP formation incubated for 3 mins by liquid chromatography-tandem mass spectrometry, Km = 3.04 μM. 23230131
KB Antiviral assay 72 hrs Antiviral activity against Pseudorabies virus infected in human KB cells assessed as inhibition of virus-induced cytopathic effect after 72 hrs by microscopically 458802
KB Antiviral assay 72 hrs Antiviral activity against Herpes simplex virus type 1 infected in human KB cells assessed as inhibition of virus-induced cytopathic effect after 72 hrs by microscopically 458802
KB Antiviral assay 72 hrs Antiviral activity against Vaccinia virus infected in human KB cells assessed as inhibition of virus-induced cytopathic effect after 72 hrs by microscopically 458802
KB Antiviral assay 72 hrs Antiviral activity against Myxoma virus infected in human KB cells assessed as inhibition of virus-induced cytopathic effect after 72 hrs by microscopically 458802
H441 Cytotoxicity assay Cytotoxicity against human H441 cells by serum lactate dehydrogenase assay 19574048
H441 Cytotoxicity assay Cytotoxicity against human H441 cells by glucosaminidase assay 19574048
KG1 Antitumor assay 100 mg/kg 11 days Antitumor activity against human KG1 cells xenografted in mouse assessed as tumor regression at 100 mg/kg, po qd measured after 11 days post tumor implantation 26505898
A673 qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for A673 cells) 29435139
P12-ICHIKAWA Growth Inhibition Assay Inhibition of human P12-ICHIKAWA cell growth in a cell viability assay, IC50 = 0.005537 μM. SANGER
697 Growth Inhibition Assay Inhibition of human 697 cell growth in a cell viability assay, IC50 = 0.0106 μM. SANGER
ES1 Growth Inhibition Assay Inhibition of human ES1 cell growth in a cell viability assay, IC50 = 0.01297 μM. SANGER
HEL Growth Inhibition Assay Inhibition of human HEL cell growth in a cell viability assay, IC50 = 0.02052 μM. SANGER
CHP-212 Growth Inhibition Assay Inhibition of human CHP-212 cell growth in a cell viability assay, IC50 = 0.03347 μM. SANGER
CTB-1 Growth Inhibition Assay Inhibition of human CTB-1 cell growth in a cell viability assay, IC50 = 0.0344 μM. SANGER
A427 Growth Inhibition Assay Inhibition of human A427 cell growth in a cell viability assay, IC50 = 0.03449 μM. SANGER
MOLT-16 Growth Inhibition Assay Inhibition of human MOLT-16 cell growth in a cell viability assay, IC50 = 0.03607 μM. SANGER
MC-IXC Growth Inhibition Assay Inhibition of human MC-IXC cell growth in a cell viability assay, IC50 = 0.04141 μM. SANGER
BHT-101 Growth Inhibition Assay Inhibition of human BHT-101 cell growth in a cell viability assay, IC50 = 0.04176 μM. SANGER
K5 Growth Inhibition Assay Inhibition of human K5 cell growth in a cell viability assay, IC50 = 0.0432 μM. SANGER
A549 Growth Inhibition Assay Inhibition of human A549 cell growth in a cell viability assay, IC50 = 0.04966 μM. SANGER
NCI-H1703 Growth Inhibition Assay Inhibition of human NCI-H1703 cell growth in a cell viability assay, IC50 = 0.04981 μM. SANGER
LB2241-RCC Growth Inhibition Assay Inhibition of human LB2241-RCC cell growth in a cell viability assay, IC50 = 0.05534 μM. SANGER
MLMA Growth Inhibition Assay Inhibition of human MLMA cell growth in a cell viability assay, IC50 = 0.05551 μM. SANGER
P30-OHK Growth Inhibition Assay Inhibition of human P30-OHK cell growth in a cell viability assay, IC50 = 0.0565 μM. SANGER
NCI-H510A Growth Inhibition Assay Inhibition of human NCI-H510A cell growth in a cell viability assay, IC50 = 0.06826 μM. SANGER
J-RT3-T3-5 Growth Inhibition Assay Inhibition of human J-RT3-T3-5 cell growth in a cell viability assay, IC50 = 0.06842 μM. SANGER
VA-ES-BJ Growth Inhibition Assay Inhibition of human VA-ES-BJ cell growth in a cell viability assay, IC50 = 0.07165 μM. SANGER
T-24 Growth Inhibition Assay Inhibition of human T-24 cell growth in a cell viability assay, IC50 = 0.07856 μM. SANGER
NB69 Growth Inhibition Assay Inhibition of human NB69 cell growth in a cell viability assay, IC50 = 0.07948 μM. SANGER
CTV-1 Growth Inhibition Assay Inhibition of human CTV-1 cell growth in a cell viability assay, IC50 = 0.08474 μM. SANGER
MEL-JUSO Growth Inhibition Assay Inhibition of human MEL-JUSO cell growth in a cell viability assay, IC50 = 0.08576 μM. SANGER
MOLT-4 Growth Inhibition Assay Inhibition of human MOLT-4 cell growth in a cell viability assay, IC50 = 0.08967 μM. SANGER
SW982 Growth Inhibition Assay Inhibition of human SW982 cell growth in a cell viability assay, IC50 = 0.09123 μM. SANGER
NCI-SNU-1 Growth Inhibition Assay Inhibition of human NCI-SNU-1 cell growth in a cell viability assay, IC50 = 0.09677 μM. SANGER
GP5d Growth Inhibition Assay Inhibition of human GP5d cell growth in a cell viability assay, IC50 = 0.10205 μM. SANGER
SAS Growth Inhibition Assay Inhibition of human SAS cell growth in a cell viability assay, IC50 = 0.10757 μM. SANGER
BFTC-905 Growth Inhibition Assay Inhibition of human BFTC-905 cell growth in a cell viability assay, IC50 = 0.10831 μM. SANGER
LB1047-RCC Growth Inhibition Assay Inhibition of human LB1047-RCC cell growth in a cell viability assay, IC50 = 0.10842 μM. SANGER
BB65-RCC Growth Inhibition Assay Inhibition of human BB65-RCC cell growth in a cell viability assay, IC50 = 0.11019 μM. SANGER
KE-37 Growth Inhibition Assay Inhibition of human KE-37 cell growth in a cell viability assay, IC50 = 0.11085 μM. SANGER
NCI-H292 Growth Inhibition Assay Inhibition of human NCI-H292 cell growth in a cell viability assay, IC50 = 0.1142 μM. SANGER
HT-1080 Growth Inhibition Assay Inhibition of human HT-1080 cell growth in a cell viability assay, IC50 = 0.11447 μM. SANGER
CAKI-1 Growth Inhibition Assay Inhibition of human CAKI-1 cell growth in a cell viability assay, IC50 = 0.12001 μM. SANGER
HMV-II Growth Inhibition Assay Inhibition of human HMV-II cell growth in a cell viability assay, IC50 = 0.12363 μM. SANGER
ES8 Growth Inhibition Assay Inhibition of human ES8 cell growth in a cell viability assay, IC50 = 0.12393 μM. SANGER
NEC8 Growth Inhibition Assay Inhibition of human NEC8 cell growth in a cell viability assay, IC50 = 0.13421 μM. SANGER
EW-1 Growth Inhibition Assay Inhibition of human EW-1 cell growth in a cell viability assay, IC50 = 0.13862 μM. SANGER
H-EMC-SS Growth Inhibition Assay Inhibition of human H-EMC-SS cell growth in a cell viability assay, IC50 = 0.14528 μM. SANGER
NTERA-S-cl-D1 Growth Inhibition Assay Inhibition of human NTERA-S-cl-D1 cell growth in a cell viability assay, IC50 = 0.1591 μM. SANGER
COR-L105 Growth Inhibition Assay Inhibition of human COR-L105 cell growth in a cell viability assay, IC50 = 0.16039 μM. SANGER
A2780 Growth Inhibition Assay Inhibition of human A2780 cell growth in a cell viability assay, IC50 = 0.16238 μM. SANGER
C2BBe1 Growth Inhibition Assay Inhibition of human C2BBe1 cell growth in a cell viability assay, IC50 = 0.16596 μM. SANGER
SK-UT-1 Growth Inhibition Assay Inhibition of human SK-UT-1 cell growth in a cell viability assay, IC50 = 0.18142 μM. SANGER
CGTH-W-1 Growth Inhibition Assay Inhibition of human CGTH-W-1 cell growth in a cell viability assay, IC50 = 0.1818 μM. SANGER
PA-1 Growth Inhibition Assay Inhibition of human PA-1 cell growth in a cell viability assay, IC50 = 0.18665 μM. SANGER
NB10 Growth Inhibition Assay Inhibition of human NB10 cell growth in a cell viability assay, IC50 = 0.18814 μM. SANGER
HCC1806 Growth Inhibition Assay Inhibition of human HCC1806 cell growth in a cell viability assay, IC50 = 0.19102 μM. SANGER
PSN1 Growth Inhibition Assay Inhibition of human PSN1 cell growth in a cell viability assay, IC50 = 0.19281 μM. SANGER
ES3 Growth Inhibition Assay Inhibition of human ES3 cell growth in a cell viability assay, IC50 = 0.1987 μM. SANGER
OVCAR-8 Growth Inhibition Assay Inhibition of human OVCAR-8 cell growth in a cell viability assay, IC50 = 0.2108 μM. SANGER
EM-2 Growth Inhibition Assay Inhibition of human EM-2 cell growth in a cell viability assay, IC50 = 0.21139 μM. SANGER
ES4 Growth Inhibition Assay Inhibition of human ES4 cell growth in a cell viability assay, IC50 = 0.21401 μM. SANGER
TE-8 Growth Inhibition Assay Inhibition of human TE-8 cell growth in a cell viability assay, IC50 = 0.2191 μM. SANGER
OVCAR-5 Growth Inhibition Assay Inhibition of human OVCAR-5 cell growth in a cell viability assay, IC50 = 0.21963 μM. SANGER
HN Growth Inhibition Assay Inhibition of human HN cell growth in a cell viability assay, IC50 = 0.2207 μM. SANGER
A673 Growth Inhibition Assay Inhibition of human A673 cell growth in a cell viability assay, IC50 = 0.22382 μM. SANGER
769-P Growth Inhibition Assay Inhibition of human 769-P cell growth in a cell viability assay, IC50 = 0.22786 μM. SANGER
LC-2-ad Growth Inhibition Assay Inhibition of human LC-2-ad cell growth in a cell viability assay, IC50 = 0.22961 μM. SANGER
SJSA-1 Growth Inhibition Assay Inhibition of human SJSA-1 cell growth in a cell viability assay, IC50 = 0.23516 μM. SANGER
HuP-T4 Growth Inhibition Assay Inhibition of human HuP-T4 cell growth in a cell viability assay, IC50 = 0.23681 μM. SANGER
ES5 Growth Inhibition Assay Inhibition of human ES5 cell growth in a cell viability assay, IC50 = 0.2429 μM. SANGER
HCT-116 Growth Inhibition Assay Inhibition of human HCT-116 cell growth in a cell viability assay, IC50 = 0.24477 μM. SANGER
DB Growth Inhibition Assay Inhibition of human DB cell growth in a cell viability assay, IC50 = 0.24595 μM. SANGER
LXF-289 Growth Inhibition Assay Inhibition of human LXF-289 cell growth in a cell viability assay, IC50 = 0.25141 μM. SANGER
ES7 Growth Inhibition Assay Inhibition of human ES7 cell growth in a cell viability assay, IC50 = 0.25716 μM. SANGER
EW-16 Growth Inhibition Assay Inhibition of human EW-16 cell growth in a cell viability assay, IC50 = 0.26588 μM. SANGER
LU-99A Growth Inhibition Assay Inhibition of human LU-99A cell growth in a cell viability assay, IC50 = 0.26643 μM. SANGER
D-566MG Growth Inhibition Assay Inhibition of human D-566MG cell growth in a cell viability assay, IC50 = 0.26904 μM. SANGER
ML-2 Growth Inhibition Assay Inhibition of human ML-2 cell growth in a cell viability assay, IC50 = 0.26965 μM. SANGER
H4 Growth Inhibition Assay Inhibition of human H4 cell growth in a cell viability assay, IC50 = 0.27445 μM. SANGER
HCE-4 Growth Inhibition Assay Inhibition of human HCE-4 cell growth in a cell viability assay, IC50 = 0.27713 μM. SANGER
ALL-PO Growth Inhibition Assay Inhibition of human ALL-PO cell growth in a cell viability assay, IC50 = 0.28709 μM. SANGER
SNU-387 Growth Inhibition Assay Inhibition of human SNU-387 cell growth in a cell viability assay, IC50 = 0.28877 μM. SANGER
LOXIMVI Growth Inhibition Assay Inhibition of human LOXIMVI cell growth in a cell viability assay, IC50 = 0.29031 μM. SANGER
YKG-1 Growth Inhibition Assay Inhibition of human YKG-1 cell growth in a cell viability assay, IC50 = 0.29831 μM. SANGER
D-423MG Growth Inhibition Assay Inhibition of human D-423MG cell growth in a cell viability assay, IC50 = 0.29851 μM. SANGER
KYSE-510 Growth Inhibition Assay Inhibition of human KYSE-510 cell growth in a cell viability assay, IC50 = 0.30633 μM. SANGER
NB14 Growth Inhibition Assay Inhibition of human NB14 cell growth in a cell viability assay, IC50 = 0.30956 μM. SANGER
A204 Growth Inhibition Assay Inhibition of human A204 cell growth in a cell viability assay, IC50 = 0.31068 μM. SANGER
23132-87 Growth Inhibition Assay Inhibition of human 23132-87 cell growth in a cell viability assay, IC50 = 0.31872 μM. SANGER
Ca9-22 Growth Inhibition Assay Inhibition of human Ca9-22 cell growth in a cell viability assay, IC50 = 0.32077 μM. SANGER
MHH-ES-1 Growth Inhibition Assay Inhibition of human MHH-ES-1 cell growth in a cell viability assay, IC50 = 0.32338 μM. SANGER
MSTO-211H Growth Inhibition Assay Inhibition of human MSTO-211H cell growth in a cell viability assay, IC50 = 0.32388 μM. SANGER
YH-13 Growth Inhibition Assay Inhibition of human YH-13 cell growth in a cell viability assay, IC50 = 0.32755 μM. SANGER
HAL-01 Growth Inhibition Assay Inhibition of human HAL-01 cell growth in a cell viability assay, IC50 = 0.32786 μM. SANGER
RH-1 Growth Inhibition Assay Inhibition of human RH-1 cell growth in a cell viability assay, IC50 = 0.32816 μM. SANGER
LAMA-84 Growth Inhibition Assay Inhibition of human LAMA-84 cell growth in a cell viability assay, IC50 = 0.33454 μM. SANGER
NBsusSR Growth Inhibition Assay Inhibition of human NBsusSR cell growth in a cell viability assay, IC50 = 0.3354 μM. SANGER
JAR Growth Inhibition Assay Inhibition of human JAR cell growth in a cell viability assay, IC50 = 0.33788 μM. SANGER
GI-1 Growth Inhibition Assay Inhibition of human GI-1 cell growth in a cell viability assay, IC50 = 0.33883 μM. SANGER
RPMI-7951 Growth Inhibition Assay Inhibition of human RPMI-7951 cell growth in a cell viability assay, IC50 = 0.33952 μM. SANGER
8-MG-BA Growth Inhibition Assay Inhibition of human 8-MG-BA cell growth in a cell viability assay, IC50 = 0.3407 μM. SANGER
GT3TKB Growth Inhibition Assay Inhibition of human GT3TKB cell growth in a cell viability assay, IC50 = 0.34071 μM. SANGER
UM-UC-3 Growth Inhibition Assay Inhibition of human UM-UC-3 cell growth in a cell viability assay, IC50 = 0.34227 μM. SANGER
U-2-OS Growth Inhibition Assay Inhibition of human U-2-OS cell growth in a cell viability assay, IC50 = 0.34387 μM. SANGER
SW620 Growth Inhibition Assay Inhibition of human SW620 cell growth in a cell viability assay, IC50 = 0.3492 μM. SANGER
HOP-92 Growth Inhibition Assay Inhibition of human HOP-92 cell growth in a cell viability assay, IC50 = 0.3544 μM. SANGER
BFTC-909 Growth Inhibition Assay Inhibition of human BFTC-909 cell growth in a cell viability assay, IC50 = 0.35736 μM. SANGER
D-283MED Growth Inhibition Assay Inhibition of human D-283MED cell growth in a cell viability assay, IC50 = 0.36027 μM. SANGER
SW48 Growth Inhibition Assay Inhibition of human SW48 cell growth in a cell viability assay, IC50 = 0.36566 μM. SANGER
ATN-1 Growth Inhibition Assay Inhibition of human ATN-1 cell growth in a cell viability assay, IC50 = 0.36571 μM. SANGER
ACHN Growth Inhibition Assay Inhibition of human ACHN cell growth in a cell viability assay, IC50 = 0.37018 μM. SANGER
LS-513 Growth Inhibition Assay Inhibition of human LS-513 cell growth in a cell viability assay, IC50 = 0.3795 μM. SANGER
TE-5 Growth Inhibition Assay Inhibition of human TE-5 cell growth in a cell viability assay, IC50 = 0.3806 μM. SANGER
IST-MEL1 Growth Inhibition Assay Inhibition of human IST-MEL1 cell growth in a cell viability assay, IC50 = 0.3808 μM. SANGER
RS4-11 Growth Inhibition Assay Inhibition of human RS4-11 cell growth in a cell viability assay, IC50 = 0.381 μM. SANGER
GR-ST Growth Inhibition Assay Inhibition of human GR-ST cell growth in a cell viability assay, IC50 = 0.38472 μM. SANGER
NCI-H1048 Growth Inhibition Assay Inhibition of human NCI-H1048 cell growth in a cell viability assay, IC50 = 0.38876 μM. SANGER
ONS-76 Growth Inhibition Assay Inhibition of human ONS-76 cell growth in a cell viability assay, IC50 = 0.39003 μM. SANGER
H9 Growth Inhibition Assay Inhibition of human H9 cell growth in a cell viability assay, IC50 = 0.39142 μM. SANGER
GAMG Growth Inhibition Assay Inhibition of human GAMG cell growth in a cell viability assay, IC50 = 0.39364 μM. SANGER
GMS-10 Growth Inhibition Assay Inhibition of human GMS-10 cell growth in a cell viability assay, IC50 = 0.39556 μM. SANGER
A375 Growth Inhibition Assay Inhibition of human A375 cell growth in a cell viability assay, IC50 = 0.39567 μM. SANGER
NCI-H1155 Growth Inhibition Assay Inhibition of human NCI-H1155 cell growth in a cell viability assay, IC50 = 0.39685 μM. SANGER
OC-314 Growth Inhibition Assay Inhibition of human OC-314 cell growth in a cell viability assay, IC50 = 0.39891 μM. SANGER
HSC-3 Growth Inhibition Assay Inhibition of human HSC-3 cell growth in a cell viability assay, IC50 = 0.39994 μM. SANGER
RPMI-2650 Growth Inhibition Assay Inhibition of human RPMI-2650 cell growth in a cell viability assay, IC50 = 0.40146 μM. SANGER
SK-PN-DW Growth Inhibition Assay Inhibition of human SK-PN-DW cell growth in a cell viability assay, IC50 = 0.41557 μM. SANGER
MZ7-mel Growth Inhibition Assay Inhibition of human MZ7-mel cell growth in a cell viability assay, IC50 = 0.41695 μM. SANGER
GOTO Growth Inhibition Assay Inhibition of human GOTO cell growth in a cell viability assay, IC50 = 0.42403 μM. SANGER
COLO-800 Growth Inhibition Assay Inhibition of human COLO-800 cell growth in a cell viability assay, IC50 = 0.42456 μM. SANGER
NCI-H2122 Growth Inhibition Assay Inhibition of human NCI-H2122 cell growth in a cell viability assay, IC50 = 0.42962 μM. SANGER
JEG-3 Growth Inhibition Assay Inhibition of human JEG-3 cell growth in a cell viability assay, IC50 = 0.43108 μM. SANGER
SK-N-AS Growth Inhibition Assay Inhibition of human SK-N-AS cell growth in a cell viability assay, IC50 = 0.45046 μM. SANGER
NB5 Growth Inhibition Assay Inhibition of human NB5 cell growth in a cell viability assay, IC50 = 0.45227 μM. SANGER
HGC-27 Growth Inhibition Assay Inhibition of human HGC-27 cell growth in a cell viability assay, IC50 = 0.45523 μM. SANGER
HTC-C3 Growth Inhibition Assay Inhibition of human HTC-C3 cell growth in a cell viability assay, IC50 = 0.45932 μM. SANGER
LK-2 Growth Inhibition Assay Inhibition of human LK-2 cell growth in a cell viability assay, IC50 = 0.46056 μM. SANGER
HSC-4 Growth Inhibition Assay Inhibition of human HSC-4 cell growth in a cell viability assay, IC50 = 0.46741 μM. SANGER
SW13 Growth Inhibition Assay Inhibition of human SW13 cell growth in a cell viability assay, IC50 = 0.47618 μM. SANGER
LCLC-97TM1 Growth Inhibition Assay Inhibition of human LCLC-97TM1 cell growth in a cell viability assay, IC50 = 0.47741 μM. SANGER
BCPAP Growth Inhibition Assay Inhibition of human BCPAP cell growth in a cell viability assay, IC50 = 0.50118 μM. SANGER
5637 Growth Inhibition Assay Inhibition of human 5637 cell growth in a cell viability assay, IC50 = 0.50148 μM. SANGER
RT-112 Growth Inhibition Assay Inhibition of human RT-112 cell growth in a cell viability assay, IC50 = 0.50193 μM. SANGER
BV-173 Growth Inhibition Assay Inhibition of human BV-173 cell growth in a cell viability assay, IC50 = 0.51551 μM. SANGER
HOS Growth Inhibition Assay Inhibition of human HOS cell growth in a cell viability assay, IC50 = 0.51822 μM. SANGER
BT-549 Growth Inhibition Assay Inhibition of human BT-549 cell growth in a cell viability assay, IC50 = 0.53102 μM. SANGER
Daoy Growth Inhibition Assay Inhibition of human Daoy cell growth in a cell viability assay, IC50 = 0.53222 μM. SANGER
MHH-PREB-1 Growth Inhibition Assay Inhibition of human MHH-PREB-1 cell growth in a cell viability assay, IC50 = 0.53311 μM. SANGER
VM-CUB-1 Growth Inhibition Assay Inhibition of human VM-CUB-1 cell growth in a cell viability assay, IC50 = 0.53346 μM. SANGER
KP-4 Growth Inhibition Assay Inhibition of human KP-4 cell growth in a cell viability assay, IC50 = 0.53574 μM. SANGER
NCI-H1623 Growth Inhibition Assay Inhibition of human NCI-H1623 cell growth in a cell viability assay, IC50 = 0.536 μM. SANGER
OCI-AML2 Growth Inhibition Assay Inhibition of human OCI-AML2 cell growth in a cell viability assay, IC50 = 0.54502 μM. SANGER
C-33-A Growth Inhibition Assay Inhibition of human C-33-A cell growth in a cell viability assay, IC50 = 0.55083 μM. SANGER
NCI-H1355 Growth Inhibition Assay Inhibition of human NCI-H1355 cell growth in a cell viability assay, IC50 = 0.55554 μM. SANGER
SK-HEP-1 Growth Inhibition Assay Inhibition of human SK-HEP-1 cell growth in a cell viability assay, IC50 = 0.55641 μM. SANGER
EC-GI-10 Growth Inhibition Assay Inhibition of human EC-GI-10 cell growth in a cell viability assay, IC50 = 0.55698 μM. SANGER
HUTU-80 Growth Inhibition Assay Inhibition of human HUTU-80 cell growth in a cell viability assay, IC50 = 0.56122 μM. SANGER
KYSE-180 Growth Inhibition Assay Inhibition of human KYSE-180 cell growth in a cell viability assay, IC50 = 0.56471 μM. SANGER
CAL-51 Growth Inhibition Assay Inhibition of human CAL-51 cell growth in a cell viability assay, IC50 = 0.57064 μM. SANGER
DU-4475 Growth Inhibition Assay Inhibition of human DU-4475 cell growth in a cell viability assay, IC50 = 0.5754 μM. SANGER
NUGC-3 Growth Inhibition Assay Inhibition of human NUGC-3 cell growth in a cell viability assay, IC50 = 0.58891 μM. SANGER
NCI-H2228 Growth Inhibition Assay Inhibition of human NCI-H2228 cell growth in a cell viability assay, IC50 = 0.59651 μM. SANGER
RKO Growth Inhibition Assay Inhibition of human RKO cell growth in a cell viability assay, IC50 = 0.59858 μM. SANGER
PC-14 Growth Inhibition Assay Inhibition of human PC-14 cell growth in a cell viability assay, IC50 = 0.6095 μM. SANGER
TI-73 Growth Inhibition Assay Inhibition of human TI-73 cell growth in a cell viability assay, IC50 = 0.61266 μM. SANGER
CW-2 Growth Inhibition Assay Inhibition of human CW-2 cell growth in a cell viability assay, IC50 = 0.61279 μM. SANGER
SN12C Growth Inhibition Assay Inhibition of human SN12C cell growth in a cell viability assay, IC50 = 0.62292 μM. SANGER
M14 Growth Inhibition Assay Inhibition of human M14 cell growth in a cell viability assay, IC50 = 0.63224 μM. SANGER
KOSC-2 Growth Inhibition Assay Inhibition of human KOSC-2 cell growth in a cell viability assay, IC50 = 0.64309 μM. SANGER
G-402 Growth Inhibition Assay Inhibition of human G-402 cell growth in a cell viability assay, IC50 = 0.64977 μM. SANGER
TYK-nu Growth Inhibition Assay Inhibition of human TYK-nu cell growth in a cell viability assay, IC50 = 0.66085 μM. SANGER
UACC-62 Growth Inhibition Assay Inhibition of human UACC-62 cell growth in a cell viability assay, IC50 = 0.66553 μM. SANGER
EW-22 Growth Inhibition Assay Inhibition of human EW-22 cell growth in a cell viability assay, IC50 = 0.66762 μM. SANGER
786-0 Growth Inhibition Assay Inhibition of human 786-0 cell growth in a cell viability assay, IC50 = 0.66871 μM. SANGER
LoVo Growth Inhibition Assay Inhibition of human LoVo cell growth in a cell viability assay, IC50 = 0.67124 μM. SANGER
NCI-H1299 Growth Inhibition Assay Inhibition of human NCI-H1299 cell growth in a cell viability assay, IC50 = 0.67177 μM. SANGER
Saos-2 Growth Inhibition Assay Inhibition of human Saos-2 cell growth in a cell viability assay, IC50 = 0.6817 μM. SANGER
SJRH30 Growth Inhibition Assay Inhibition of human SJRH30 cell growth in a cell viability assay, IC50 = 0.68338 μM. SANGER
A2058 Growth Inhibition Assay Inhibition of human A2058 cell growth in a cell viability assay, IC50 = 0.68678 μM. SANGER
HO-1-N-1 Growth Inhibition Assay Inhibition of human HO-1-N-1 cell growth in a cell viability assay, IC50 = 0.69055 μM. SANGER
SF126 Growth Inhibition Assay Inhibition of human SF126 cell growth in a cell viability assay, IC50 = 0.69317 μM. SANGER
LS-411N Growth Inhibition Assay Inhibition of human LS-411N cell growth in a cell viability assay, IC50 = 0.69527 μM. SANGER
RXF393 Growth Inhibition Assay Inhibition of human RXF393 cell growth in a cell viability assay, IC50 = 0.70032 μM. SANGER
CAL-62 Growth Inhibition Assay Inhibition of human CAL-62 cell growth in a cell viability assay, IC50 = 0.70983 μM. SANGER
SF539 Growth Inhibition Assay Inhibition of human SF539 cell growth in a cell viability assay, IC50 = 0.71677 μM. SANGER
SW756 Growth Inhibition Assay Inhibition of human SW756 cell growth in a cell viability assay, IC50 = 0.71942 μM. SANGER
ES6 Growth Inhibition Assay Inhibition of human ES6 cell growth in a cell viability assay, IC50 = 0.72144 μM. SANGER
MHH-NB-11 Growth Inhibition Assay Inhibition of human MHH-NB-11 cell growth in a cell viability assay, IC50 = 0.72787 μM. SANGER
A388 Growth Inhibition Assay Inhibition of human A388 cell growth in a cell viability assay, IC50 = 0.73992 μM. SANGER
RPMI-8866 Growth Inhibition Assay Inhibition of human RPMI-8866 cell growth in a cell viability assay, IC50 = 0.74014 μM. SANGER
HD-MY-Z Growth Inhibition Assay Inhibition of human HD-MY-Z cell growth in a cell viability assay, IC50 = 0.74471 μM. SANGER
G-401 Growth Inhibition Assay Inhibition of human G-401 cell growth in a cell viability assay, IC50 = 0.75823 μM. SANGER
EW-24 Growth Inhibition Assay Inhibition of human EW-24 cell growth in a cell viability assay, IC50 = 0.79393 μM. SANGER
COR-L23 Growth Inhibition Assay Inhibition of human COR-L23 cell growth in a cell viability assay, IC50 = 0.79673 μM. SANGER
NCI-H1437 Growth Inhibition Assay Inhibition of human NCI-H1437 cell growth in a cell viability assay, IC50 = 0.79806 μM. SANGER
SK-MEL-28 Growth Inhibition Assay Inhibition of human SK-MEL-28 cell growth in a cell viability assay, IC50 = 0.79873 μM. SANGER
PANC-10-05 Growth Inhibition Assay Inhibition of human PANC-10-05 cell growth in a cell viability assay, IC50 = 0.80176 μM. SANGER
EoL-1-cell Growth Inhibition Assay Inhibition of human EoL-1-cell cell growth in a cell viability assay, IC50 = 0.8031 μM. SANGER
D-336MG Growth Inhibition Assay Inhibition of human D-336MG cell growth in a cell viability assay, IC50 = 0.80494 μM. SANGER
SK-MES-1 Growth Inhibition Assay Inhibition of human SK-MES-1 cell growth in a cell viability assay, IC50 = 0.80682 μM. SANGER
COLO-668 Growth Inhibition Assay Inhibition of human COLO-668 cell growth in a cell viability assay, IC50 = 0.80916 μM. SANGER
BE-13 Growth Inhibition Assay Inhibition of human BE-13 cell growth in a cell viability assay, IC50 = 0.8245 μM. SANGER
EW-3 Growth Inhibition Assay Inhibition of human EW-3 cell growth in a cell viability assay, IC50 = 0.82999 μM. SANGER
OMC-1 Growth Inhibition Assay Inhibition of human OMC-1 cell growth in a cell viability assay, IC50 = 0.83236 μM. SANGER
Hs-578-T Growth Inhibition Assay Inhibition of human Hs-578-T cell growth in a cell viability assay, IC50 = 0.83886 μM. SANGER
A3-KAW Growth Inhibition Assay Inhibition of human A3-KAW cell growth in a cell viability assay, IC50 = 0.84424 μM. SANGER
KYSE-270 Growth Inhibition Assay Inhibition of human KYSE-270 cell growth in a cell viability assay, IC50 = 0.84868 μM. SANGER
HuP-T3 Growth Inhibition Assay Inhibition of human HuP-T3 cell growth in a cell viability assay, IC50 = 0.85567 μM. SANGER
GCT Growth Inhibition Assay Inhibition of human GCT cell growth in a cell viability assay, IC50 = 0.85568 μM. SANGER
SiHa Growth Inhibition Assay Inhibition of human SiHa cell growth in a cell viability assay, IC50 = 0.85606 μM. SANGER
Ramos-2G6-4C10 Growth Inhibition Assay Inhibition of human Ramos-2G6-4C10 cell growth in a cell viability assay, IC50 = 0.86757 μM. SANGER
DEL Growth Inhibition Assay Inhibition of human DEL cell growth in a cell viability assay, IC50 = 0.87485 μM. SANGER
SNU-423 Growth Inhibition Assay Inhibition of human SNU-423 cell growth in a cell viability assay, IC50 = 0.8808 μM. SANGER
PANC-03-27 Growth Inhibition Assay Inhibition of human PANC-03-27 cell growth in a cell viability assay, IC50 = 0.89662 μM. SANGER
BHY Growth Inhibition Assay Inhibition of human BHY cell growth in a cell viability assay, IC50 = 0.89762 μM. SANGER
DOK Growth Inhibition Assay Inhibition of human DOK cell growth in a cell viability assay, IC50 = 0.90446 μM. SANGER
SKG-IIIa Growth Inhibition Assay Inhibition of human SKG-IIIa cell growth in a cell viability assay, IC50 = 0.91503 μM. SANGER
AGS Growth Inhibition Assay Inhibition of human AGS cell growth in a cell viability assay, IC50 = 0.91755 μM. SANGER
MN-60 Growth Inhibition Assay Inhibition of human MN-60 cell growth in a cell viability assay, IC50 = 0.93484 μM. SANGER
CAL-54 Growth Inhibition Assay Inhibition of human CAL-54 cell growth in a cell viability assay, IC50 = 0.94033 μM. SANGER
KMOE-2 Growth Inhibition Assay Inhibition of human KMOE-2 cell growth in a cell viability assay, IC50 = 0.94389 μM. SANGER
SCC-4 Growth Inhibition Assay Inhibition of human SCC-4 cell growth in a cell viability assay, IC50 = 0.96513 μM. SANGER
CAL-39 Growth Inhibition Assay Inhibition of human CAL-39 cell growth in a cell viability assay, IC50 = 0.99829 μM. SANGER
CHL-1 Growth Inhibition Assay Inhibition of human CHL-1 cell growth in a cell viability assay, IC50 = 1.04316 μM. SANGER
NCI-H2030 Growth Inhibition Assay Inhibition of human NCI-H2030 cell growth in a cell viability assay, IC50 = 1.04946 μM. SANGER
COLO-792 Growth Inhibition Assay Inhibition of human COLO-792 cell growth in a cell viability assay, IC50 = 1.05355 μM. SANGER
CFPAC-1 Growth Inhibition Assay Inhibition of human CFPAC-1 cell growth in a cell viability assay, IC50 = 1.05515 μM. SANGER
NKM-1 Growth Inhibition Assay Inhibition of human NKM-1 cell growth in a cell viability assay, IC50 = 1.06403 μM. SANGER
SK-N-DZ Growth Inhibition Assay Inhibition of human SK-N-DZ cell growth in a cell viability assay, IC50 = 1.07213 μM. SANGER
HC-1 Growth Inhibition Assay Inhibition of human HC-1 cell growth in a cell viability assay, IC50 = 1.07779 μM. SANGER
SCC-15 Growth Inhibition Assay Inhibition of human SCC-15 cell growth in a cell viability assay, IC50 = 1.08069 μM. SANGER
D-247MG Growth Inhibition Assay Inhibition of human D-247MG cell growth in a cell viability assay, IC50 = 1.08967 μM. SANGER
KYSE-450 Growth Inhibition Assay Inhibition of human KYSE-450 cell growth in a cell viability assay, IC50 = 1.09059 μM. SANGER
Becker Growth Inhibition Assay Inhibition of human Becker cell growth in a cell viability assay, IC50 = 1.09665 μM. SANGER
EGI-1 Growth Inhibition Assay Inhibition of human EGI-1 cell growth in a cell viability assay, IC50 = 1.10918 μM. SANGER
U251 Growth Inhibition Assay Inhibition of human U251 cell growth in a cell viability assay, IC50 = 1.12999 μM. SANGER
KG-1 Growth Inhibition Assay Inhibition of human KG-1 cell growth in a cell viability assay, IC50 = 1.15685 μM. SANGER
NH-12 Growth Inhibition Assay Inhibition of human NH-12 cell growth in a cell viability assay, IC50 = 1.16227 μM. SANGER
D-263MG Growth Inhibition Assay Inhibition of human D-263MG cell growth in a cell viability assay, IC50 = 1.1717 μM. SANGER
A4-Fuk Growth Inhibition Assay Inhibition of human A4-Fuk cell growth in a cell viability assay, IC50 = 1.17349 μM. SANGER
CAL-33 Growth Inhibition Assay Inhibition of human CAL-33 cell growth in a cell viability assay, IC50 = 1.17622 μM. SANGER
NCI-H23 Growth Inhibition Assay Inhibition of human NCI-H23 cell growth in a cell viability assay, IC50 = 1.19572 μM. SANGER
EW-11 Growth Inhibition Assay Inhibition of human EW-11 cell growth in a cell viability assay, IC50 = 1.21388 μM. SANGER
HT-144 Growth Inhibition Assay Inhibition of human HT-144 cell growth in a cell viability assay, IC50 = 1.23101 μM. SANGER
647-V Growth Inhibition Assay Inhibition of human 647-V cell growth in a cell viability assay, IC50 = 1.23274 μM. SANGER
Mewo Growth Inhibition Assay Inhibition of human Mewo cell growth in a cell viability assay, IC50 = 1.23969 μM. SANGER
OAW-42 Growth Inhibition Assay Inhibition of human OAW-42 cell growth in a cell viability assay, IC50 = 1.24927 μM. SANGER
U031 Growth Inhibition Assay Inhibition of human U031 cell growth in a cell viability assay, IC50 = 1.25079 μM. SANGER
RD Growth Inhibition Assay Inhibition of human RD cell growth in a cell viability assay, IC50 = 1.27311 μM. SANGER
PC-3 Growth Inhibition Assay Inhibition of human PC-3 cell growth in a cell viability assay, IC50 = 1.27636 μM. SANGER
MC116 Growth Inhibition Assay Inhibition of human MC116 cell growth in a cell viability assay, IC50 = 1.28349 μM. SANGER
LNCaP-Clone-FGC Growth Inhibition Assay Inhibition of human LNCaP-Clone-FGC cell growth in a cell viability assay, IC50 = 1.31198 μM. SANGER
SK-LU-1 Growth Inhibition Assay Inhibition of human SK-LU-1 cell growth in a cell viability assay, IC50 = 1.31214 μM. SANGER
MPP-89 Growth Inhibition Assay Inhibition of human MPP-89 cell growth in a cell viability assay, IC50 = 1.31316 μM. SANGER
SW780 Growth Inhibition Assay Inhibition of human SW780 cell growth in a cell viability assay, IC50 = 1.32041 μM. SANGER
HuO-3N1 Growth Inhibition Assay Inhibition of human HuO-3N1 cell growth in a cell viability assay, IC50 = 1.32628 μM. SANGER
L-363 Growth Inhibition Assay Inhibition of human L-363 cell growth in a cell viability assay, IC50 = 1.33929 μM. SANGER
VMRC-RCZ Growth Inhibition Assay Inhibition of human VMRC-RCZ cell growth in a cell viability assay, IC50 = 1.35399 μM. SANGER
SF268 Growth Inhibition Assay Inhibition of human SF268 cell growth in a cell viability assay, IC50 = 1.36068 μM. SANGER
DOHH-2 Growth Inhibition Assay Inhibition of human DOHH-2 cell growth in a cell viability assay, IC50 = 1.3786 μM. SANGER
HT-3 Growth Inhibition Assay Inhibition of human HT-3 cell growth in a cell viability assay, IC50 = 1.38152 μM. SANGER
FTC-133 Growth Inhibition Assay Inhibition of human FTC-133 cell growth in a cell viability assay, IC50 = 1.38559 μM. SANGER
MDA-MB-157 Growth Inhibition Assay Inhibition of human MDA-MB-157 cell growth in a cell viability assay, IC50 = 1.38917 μM. SANGER
AsPC-1 Growth Inhibition Assay Inhibition of human AsPC-1 cell growth in a cell viability assay, IC50 = 1.39216 μM. SANGER
NCI-H1792 Growth Inhibition Assay Inhibition of human NCI-H1792 cell growth in a cell viability assay, IC50 = 1.42426 μM. SANGER
MZ2-MEL Growth Inhibition Assay Inhibition of human MZ2-MEL cell growth in a cell viability assay, IC50 = 1.43438 μM. SANGER
EPLC-272H Growth Inhibition Assay Inhibition of human EPLC-272H cell growth in a cell viability assay, IC50 = 1.44992 μM. SANGER
JVM-3 Growth Inhibition Assay Inhibition of human JVM-3 cell growth in a cell viability assay, IC50 = 1.4541 μM. SANGER
HSC-2 Growth Inhibition Assay Inhibition of human HSC-2 cell growth in a cell viability assay, IC50 = 1.45612 μM. SANGER
DMS-273 Growth Inhibition Assay Inhibition of human DMS-273 cell growth in a cell viability assay, IC50 = 1.45632 μM. SANGER
AM-38 Growth Inhibition Assay Inhibition of human AM-38 cell growth in a cell viability assay, IC50 = 1.46755 μM. SANGER
MIA-PaCa-2 Growth Inhibition Assay Inhibition of human MIA-PaCa-2 cell growth in a cell viability assay, IC50 = 1.48862 μM. SANGER
NB7 Growth Inhibition Assay Inhibition of human NB7 cell growth in a cell viability assay, IC50 = 1.51552 μM. SANGER
ABC-1 Growth Inhibition Assay Inhibition of human ABC-1 cell growth in a cell viability assay, IC50 = 1.52053 μM. SANGER
EFO-21 Growth Inhibition Assay Inhibition of human EFO-21 cell growth in a cell viability assay, IC50 = 1.54986 μM. SANGER
NCI-H1666 Growth Inhibition Assay Inhibition of human NCI-H1666 cell growth in a cell viability assay, IC50 = 1.5762 μM. SANGER
OS-RC-2 Growth Inhibition Assay Inhibition of human OS-RC-2 cell growth in a cell viability assay, IC50 = 1.58228 μM. SANGER
HLE Growth Inhibition Assay Inhibition of human HLE cell growth in a cell viability assay, IC50 = 1.59175 μM. SANGER
DoTc2-4510 Growth Inhibition Assay Inhibition of human DoTc2-4510 cell growth in a cell viability assay, IC50 = 1.59856 μM. SANGER
J82 Growth Inhibition Assay Inhibition of human J82 cell growth in a cell viability assay, IC50 = 1.61802 μM. SANGER
SW900 Growth Inhibition Assay Inhibition of human SW900 cell growth in a cell viability assay, IC50 = 1.62161 μM. SANGER
MKN45 Growth Inhibition Assay Inhibition of human MKN45 cell growth in a cell viability assay, IC50 = 1.64811 μM. SANGER
GI-ME-N Growth Inhibition Assay Inhibition of human GI-ME-N cell growth in a cell viability assay, IC50 = 1.65967 μM. SANGER
DMS-114 Growth Inhibition Assay Inhibition of human DMS-114 cell growth in a cell viability assay, IC50 = 1.68124 μM. SANGER
HT-1376 Growth Inhibition Assay Inhibition of human HT-1376 cell growth in a cell viability assay, IC50 = 1.68168 μM. SANGER
T98G Growth Inhibition Assay Inhibition of human T98G cell growth in a cell viability assay, IC50 = 1.71811 μM. SANGER
SW1710 Growth Inhibition Assay Inhibition of human SW1710 cell growth in a cell viability assay, IC50 = 1.72915 μM. SANGER
TGBC11TKB Growth Inhibition Assay Inhibition of human TGBC11TKB cell growth in a cell viability assay, IC50 = 1.73145 μM. SANGER
TK10 Growth Inhibition Assay Inhibition of human TK10 cell growth in a cell viability assay, IC50 = 1.73331 μM. SANGER
NCI-H661 Growth Inhibition Assay Inhibition of human NCI-H661 cell growth in a cell viability assay, IC50 = 1.73446 μM. SANGER
MKN1 Growth Inhibition Assay Inhibition of human MKN1 cell growth in a cell viability assay, IC50 = 1.73948 μM. SANGER
U-87-MG Growth Inhibition Assay Inhibition of human U-87-MG cell growth in a cell viability assay, IC50 = 1.74257 μM. SANGER
RERF-LC-MS Growth Inhibition Assay Inhibition of human RERF-LC-MS cell growth in a cell viability assay, IC50 = 1.76445 μM. SANGER
NCI-H1581 Growth Inhibition Assay Inhibition of human NCI-H1581 cell growth in a cell viability assay, IC50 = 1.76955 μM. SANGER
IGR-1 Growth Inhibition Assay Inhibition of human IGR-1 cell growth in a cell viability assay, IC50 = 1.78279 μM. SANGER
TE-9 Growth Inhibition Assay Inhibition of human TE-9 cell growth in a cell viability assay, IC50 = 1.78754 μM. SANGER
HEC-1 Growth Inhibition Assay Inhibition of human HEC-1 cell growth in a cell viability assay, IC50 = 1.78799 μM. SANGER
IGROV-1 Growth Inhibition Assay Inhibition of human IGROV-1 cell growth in a cell viability assay, IC50 = 1.78989 μM. SANGER
OE33 Growth Inhibition Assay Inhibition of human OE33 cell growth in a cell viability assay, IC50 = 1.80243 μM. SANGER
MZ1-PC Growth Inhibition Assay Inhibition of human MZ1-PC cell growth in a cell viability assay, IC50 = 1.80338 μM. SANGER
NCI-H28 Growth Inhibition Assay Inhibition of human NCI-H28 cell growth in a cell viability assay, IC50 = 1.82221 μM. SANGER
M059J Growth Inhibition Assay Inhibition of human M059J cell growth in a cell viability assay, IC50 = 1.82297 μM. SANGER
AN3-CA Growth Inhibition Assay Inhibition of human AN3-CA cell growth in a cell viability assay, IC50 = 1.84009 μM. SANGER
MV-4-11 Growth Inhibition Assay Inhibition of human MV-4-11 cell growth in a cell viability assay, IC50 = 1.8467 μM. SANGER
TGBC24TKB Growth Inhibition Assay Inhibition of human TGBC24TKB cell growth in a cell viability assay, IC50 = 1.8517 μM. SANGER
KYSE-70 Growth Inhibition Assay Inhibition of human KYSE-70 cell growth in a cell viability assay, IC50 = 1.85716 μM. SANGER
COLO-829 Growth Inhibition Assay Inhibition of human COLO-829 cell growth in a cell viability assay, IC50 = 1.86471 μM. SANGER
HCC38 Growth Inhibition Assay Inhibition of human HCC38 cell growth in a cell viability assay, IC50 = 1.87965 μM. SANGER
NOS-1 Growth Inhibition Assay Inhibition of human NOS-1 cell growth in a cell viability assay, IC50 = 1.90764 μM. SANGER
CAL-27 Growth Inhibition Assay Inhibition of human CAL-27 cell growth in a cell viability assay, IC50 = 1.92856 μM. SANGER
EFO-27 Growth Inhibition Assay Inhibition of human EFO-27 cell growth in a cell viability assay, IC50 = 1.93966 μM. SANGER
NMC-G1 Growth Inhibition Assay Inhibition of human NMC-G1 cell growth in a cell viability assay, IC50 = 1.95708 μM. SANGER
EW-13 Growth Inhibition Assay Inhibition of human EW-13 cell growth in a cell viability assay, IC50 = 1.9815 μM. SANGER
MDA-MB-175-VII Growth Inhibition Assay Inhibition of human MDA-MB-175-VII cell growth in a cell viability assay, IC50 = 1.99141 μM. SANGER
MCF7 Growth Inhibition Assay Inhibition of human MCF7 cell growth in a cell viability assay, IC50 = 2.00248 μM. SANGER
Detroit562 Growth Inhibition Assay Inhibition of human Detroit562 cell growth in a cell viability assay, IC50 = 2.0621 μM. SANGER
KNS-62 Growth Inhibition Assay Inhibition of human KNS-62 cell growth in a cell viability assay, IC50 = 2.07553 μM. SANGER
MDA-MB-453 Growth Inhibition Assay Inhibition of human MDA-MB-453 cell growth in a cell viability assay, IC50 = 2.10739 μM. SANGER
KASUMI-1 Growth Inhibition Assay Inhibition of human KASUMI-1 cell growth in a cell viability assay, IC50 = 2.16268 μM. SANGER
FADU Growth Inhibition Assay Inhibition of human FADU cell growth in a cell viability assay, IC50 = 2.16998 μM. SANGER
KYSE-410 Growth Inhibition Assay Inhibition of human KYSE-410 cell growth in a cell viability assay, IC50 = 2.19194 μM. SANGER
IST-SL1 Growth Inhibition Assay Inhibition of human IST-SL1 cell growth in a cell viability assay, IC50 = 2.20154 μM. SANGER
NCI-H2009 Growth Inhibition Assay Inhibition of human NCI-H2009 cell growth in a cell viability assay, IC50 = 2.25295 μM. SANGER
ETK-1 Growth Inhibition Assay Inhibition of human ETK-1 cell growth in a cell viability assay, IC50 = 2.3042 μM. SANGER
COLO-741 Growth Inhibition Assay Inhibition of human COLO-741 cell growth in a cell viability assay, IC50 = 2.32544 μM. SANGER
NOMO-1 Growth Inhibition Assay Inhibition of human NOMO-1 cell growth in a cell viability assay, IC50 = 2.33232 μM. SANGER
KU812 Growth Inhibition Assay Inhibition of human KU812 cell growth in a cell viability assay, IC50 = 2.3578 μM. SANGER
MEG-01 Growth Inhibition Assay Inhibition of human MEG-01 cell growth in a cell viability assay, IC50 = 2.38965 μM. SANGER
NCI-H1755 Growth Inhibition Assay Inhibition of human NCI-H1755 cell growth in a cell viability assay, IC50 = 2.41912 μM. SANGER
MKN28 Growth Inhibition Assay Inhibition of human MKN28 cell growth in a cell viability assay, IC50 = 2.41927 μM. SANGER
HL-60 Growth Inhibition Assay Inhibition of human HL-60 cell growth in a cell viability assay, IC50 = 2.44486 μM. SANGER
SCC-9 Growth Inhibition Assay Inhibition of human SCC-9 cell growth in a cell viability assay, IC50 = 2.44796 μM. SANGER
NCI-H226 Growth Inhibition Assay Inhibition of human NCI-H226 cell growth in a cell viability assay, IC50 = 2.52099 μM. SANGER
KYSE-520 Growth Inhibition Assay Inhibition of human KYSE-520 cell growth in a cell viability assay, IC50 = 2.54159 μM. SANGER
MG-63 Growth Inhibition Assay Inhibition of human MG-63 cell growth in a cell viability assay, IC50 = 2.55986 μM. SANGER
HCC2998 Growth Inhibition Assay Inhibition of human HCC2998 cell growth in a cell viability assay, IC50 = 2.57816 μM. SANGER
DBTRG-05MG Growth Inhibition Assay Inhibition of human DBTRG-05MG cell growth in a cell viability assay, IC50 = 2.61987 μM. SANGER
HH Growth Inhibition Assay Inhibition of human HH cell growth in a cell viability assay, IC50 = 2.64005 μM. SANGER
CAS-1 Growth Inhibition Assay Inhibition of human CAS-1 cell growth in a cell viability assay, IC50 = 2.64247 μM. SANGER
NCI-N87 Growth Inhibition Assay Inhibition of human NCI-N87 cell growth in a cell viability assay, IC50 = 2.67652 μM. SANGER
SW1573 Growth Inhibition Assay Inhibition of human SW1573 cell growth in a cell viability assay, IC50 = 2.67671 μM. SANGER
LU-134-A Growth Inhibition Assay Inhibition of human LU-134-A cell growth in a cell viability assay, IC50 = 2.72472 μM. SANGER
KYSE-140 Growth Inhibition Assay Inhibition of human KYSE-140 cell growth in a cell viability assay, IC50 = 2.7526 μM. SANGER
22RV1 Growth Inhibition Assay Inhibition of human 22RV1 cell growth in a cell viability assay, IC50 = 2.7581 μM. SANGER
SW626 Growth Inhibition Assay Inhibition of human SW626 cell growth in a cell viability assay, IC50 = 2.7603 μM. SANGER
MS-1 Growth Inhibition Assay Inhibition of human MS-1 cell growth in a cell viability assay, IC50 = 2.76845 μM. SANGER
ACN Growth Inhibition Assay Inhibition of human ACN cell growth in a cell viability assay, IC50 = 2.79438 μM. SANGER
GCIY Growth Inhibition Assay Inhibition of human GCIY cell growth in a cell viability assay, IC50 = 2.80234 μM. SANGER
Ca-Ski Growth Inhibition Assay Inhibition of human Ca-Ski cell growth in a cell viability assay, IC50 = 2.86167 μM. SANGER
SK-MEL-1 Growth Inhibition Assay Inhibition of human SK-MEL-1 cell growth in a cell viability assay, IC50 = 2.90249 μM. SANGER
S-117 Growth Inhibition Assay Inhibition of human S-117 cell growth in a cell viability assay, IC50 = 2.92422 μM. SANGER
HuCCT1 Growth Inhibition Assay Inhibition of human HuCCT1 cell growth in a cell viability assay, IC50 = 2.93645 μM. SANGER
TE-11 Growth Inhibition Assay Inhibition of human TE-11 cell growth in a cell viability assay, IC50 = 2.95427 μM. SANGER
MFH-ino Growth Inhibition Assay Inhibition of human MFH-ino cell growth in a cell viability assay, IC50 = 2.956 μM. SANGER
MDA-MB-415 Growth Inhibition Assay Inhibition of human MDA-MB-415 cell growth in a cell viability assay, IC50 = 2.9585 μM. SANGER
EFM-19 Growth Inhibition Assay Inhibition of human EFM-19 cell growth in a cell viability assay, IC50 = 2.98059 μM. SANGER
NCI-H2405 Growth Inhibition Assay Inhibition of human NCI-H2405 cell growth in a cell viability assay, IC50 = 3.00449 μM. SANGER
HCC1395 Growth Inhibition Assay Inhibition of human HCC1395 cell growth in a cell viability assay, IC50 = 3.0071 μM. SANGER
NCI-H2452 Growth Inhibition Assay Inhibition of human NCI-H2452 cell growth in a cell viability assay, IC50 = 3.12218 μM. SANGER
CAL-72 Growth Inhibition Assay Inhibition of human CAL-72 cell growth in a cell viability assay, IC50 = 3.1454 μM. SANGER
LB2518-MEL Growth Inhibition Assay Inhibition of human LB2518-MEL cell growth in a cell viability assay, IC50 = 3.20734 μM. SANGER
NCI-H1395 Growth Inhibition Assay Inhibition of human NCI-H1395 cell growth in a cell viability assay, IC50 = 3.24713 μM. SANGER
SCH Growth Inhibition Assay Inhibition of human SCH cell growth in a cell viability assay, IC50 = 3.26893 μM. SANGER
CAPAN-1 Growth Inhibition Assay Inhibition of human CAPAN-1 cell growth in a cell viability assay, IC50 = 3.27528 μM. SANGER
HT55 Growth Inhibition Assay Inhibition of human HT55 cell growth in a cell viability assay, IC50 = 3.28944 μM. SANGER
NCI-H747 Growth Inhibition Assay Inhibition of human NCI-H747 cell growth in a cell viability assay, IC50 = 3.29752 μM. SANGER
TCCSUP Growth Inhibition Assay Inhibition of human TCCSUP cell growth in a cell viability assay, IC50 = 3.30446 μM. SANGER
SW1088 Growth Inhibition Assay Inhibition of human SW1088 cell growth in a cell viability assay, IC50 = 3.31361 μM. SANGER
NCI-H2170 Growth Inhibition Assay Inhibition of human NCI-H2170 cell growth in a cell viability assay, IC50 = 3.35641 μM. SANGER
D-392MG Growth Inhibition Assay Inhibition of human D-392MG cell growth in a cell viability assay, IC50 = 3.40336 μM. SANGER
DSH1 Growth Inhibition Assay Inhibition of human DSH1 cell growth in a cell viability assay, IC50 = 3.40884 μM. SANGER
AU565 Growth Inhibition Assay Inhibition of human AU565 cell growth in a cell viability assay, IC50 = 3.47021 μM. SANGER
A172 Growth Inhibition Assay Inhibition of human A172 cell growth in a cell viability assay, IC50 = 3.5178 μM. SANGER
HT-29 Growth Inhibition Assay Inhibition of human HT-29 cell growth in a cell viability assay, IC50 = 3.52424 μM. SANGER
SK-NEP-1 Growth Inhibition Assay Inhibition of human SK-NEP-1 cell growth in a cell viability assay, IC50 = 3.54517 μM. SANGER
IST-MES1 Growth Inhibition Assay Inhibition of human IST-MES1 cell growth in a cell viability assay, IC50 = 3.55449 μM. SANGER
KARPAS-45 Growth Inhibition Assay Inhibition of human KARPAS-45 cell growth in a cell viability assay, IC50 = 3.60977 μM. SANGER
HCC70 Growth Inhibition Assay Inhibition of human HCC70 cell growth in a cell viability assay, IC50 = 3.62428 μM. SANGER
BPH-1 Growth Inhibition Assay Inhibition of human BPH-1 cell growth in a cell viability assay, IC50 = 3.64205 μM. SANGER
8505C Growth Inhibition Assay Inhibition of human 8505C cell growth in a cell viability assay, IC50 = 3.70201 μM. SANGER
A498 Growth Inhibition Assay Inhibition of human A498 cell growth in a cell viability assay, IC50 = 3.72949 μM. SANGER
SW962 Growth Inhibition Assay Inhibition of human SW962 cell growth in a cell viability assay, IC50 = 3.73962 μM. SANGER
SW1990 Growth Inhibition Assay Inhibition of human SW1990 cell growth in a cell viability assay, IC50 = 3.82795 μM. SANGER
HuO9 Growth Inhibition Assay Inhibition of human HuO9 cell growth in a cell viability assay, IC50 = 3.85347 μM. SANGER
NCI-H446 Growth Inhibition Assay Inhibition of human NCI-H446 cell growth in a cell viability assay, IC50 = 3.9054 μM. SANGER
TE-10 Growth Inhibition Assay Inhibition of human TE-10 cell growth in a cell viability assay, IC50 = 3.90867 μM. SANGER
WM-115 Growth Inhibition Assay Inhibition of human WM-115 cell growth in a cell viability assay, IC50 = 3.99333 μM. SANGER
RCM-1 Growth Inhibition Assay Inhibition of human RCM-1 cell growth in a cell viability assay, IC50 = 4.01309 μM. SANGER
SK-MEL-2 Growth Inhibition Assay Inhibition of human SK-MEL-2 cell growth in a cell viability assay, IC50 = 4.0281 μM. SANGER
SF295 Growth Inhibition Assay Inhibition of human SF295 cell growth in a cell viability assay, IC50 = 4.03391 μM. SANGER
KINGS-1 Growth Inhibition Assay Inhibition of human KINGS-1 cell growth in a cell viability assay, IC50 = 4.05297 μM. SANGER
NCI-H2052 Growth Inhibition Assay Inhibition of human NCI-H2052 cell growth in a cell viability assay, IC50 = 4.05679 μM. SANGER
NCI-H1650 Growth Inhibition Assay Inhibition of human NCI-H1650 cell growth in a cell viability assay, IC50 = 4.13216 μM. SANGER
U-118-MG Growth Inhibition Assay Inhibition of human U-118-MG cell growth in a cell viability assay, IC50 = 4.15547 μM. SANGER
MDA-MB-361 Growth Inhibition Assay Inhibition of human MDA-MB-361 cell growth in a cell viability assay, IC50 = 4.22726 μM. SANGER
HCC1419 Growth Inhibition Assay Inhibition of human HCC1419 cell growth in a cell viability assay, IC50 = 4.26266 μM. SANGER
OCUB-M Growth Inhibition Assay Inhibition of human OCUB-M cell growth in a cell viability assay, IC50 = 4.28414 μM. SANGER
BxPC-3 Growth Inhibition Assay Inhibition of human BxPC-3 cell growth in a cell viability assay, IC50 = 4.29914 μM. SANGER
HT-1197 Growth Inhibition Assay Inhibition of human HT-1197 cell growth in a cell viability assay, IC50 = 4.31327 μM. SANGER
NCI-H526 Growth Inhibition Assay Inhibition of human NCI-H526 cell growth in a cell viability assay, IC50 = 4.33328 μM. SANGER
KS-1 Growth Inhibition Assay Inhibition of human KS-1 cell growth in a cell viability assay, IC50 = 4.34468 μM. SANGER
NCI-H650 Growth Inhibition Assay Inhibition of human NCI-H650 cell growth in a cell viability assay, IC50 = 4.35377 μM. SANGER
KU-19-19 Growth Inhibition Assay Inhibition of human KU-19-19 cell growth in a cell viability assay, IC50 = 4.42891 μM. SANGER
UACC-257 Growth Inhibition Assay Inhibition of human UACC-257 cell growth in a cell viability assay, IC50 = 4.46437 μM. SANGER
TGBC1TKB Growth Inhibition Assay Inhibition of human TGBC1TKB cell growth in a cell viability assay, IC50 = 4.5212 μM. SANGER
LB831-BLC Growth Inhibition Assay Inhibition of human LB831-BLC cell growth in a cell viability assay, IC50 = 4.58569 μM. SANGER
SW1783 Growth Inhibition Assay Inhibition of human SW1783 cell growth in a cell viability assay, IC50 = 4.61383 μM. SANGER
NCI-H2347 Growth Inhibition Assay Inhibition of human NCI-H2347 cell growth in a cell viability assay, IC50 = 4.63698 μM. SANGER
RCC10RGB Growth Inhibition Assay Inhibition of human RCC10RGB cell growth in a cell viability assay, IC50 = 4.68428 μM. SANGER
A101D Growth Inhibition Assay Inhibition of human A101D cell growth in a cell viability assay, IC50 = 4.76358 μM. SANGER
NCI-H2087 Growth Inhibition Assay Inhibition of human NCI-H2087 cell growth in a cell viability assay, IC50 = 4.80595 μM. SANGER
NCI-H1651 Growth Inhibition Assay Inhibition of human NCI-H1651 cell growth in a cell viability assay, IC50 = 4.98474 μM. SANGER
SK-N-FI Growth Inhibition Assay Inhibition of human SK-N-FI cell growth in a cell viability assay, IC50 = 5.06408 μM. SANGER
SW1116 Growth Inhibition Assay Inhibition of human SW1116 cell growth in a cell viability assay, IC50 = 5.12 μM. SANGER
C3A Growth Inhibition Assay Inhibition of human C3A cell growth in a cell viability assay, IC50 = 5.23422 μM. SANGER
SNU-449 Growth Inhibition Assay Inhibition of human SNU-449 cell growth in a cell viability assay, IC50 = 5.30865 μM. SANGER
NCI-H630 Growth Inhibition Assay Inhibition of human NCI-H630 cell growth in a cell viability assay, IC50 = 5.34812 μM. SANGER
DK-MG Growth Inhibition Assay Inhibition of human DK-MG cell growth in a cell viability assay, IC50 = 5.39082 μM. SANGER
YAPC Growth Inhibition Assay Inhibition of human YAPC cell growth in a cell viability assay, IC50 = 5.44769 μM. SANGER
BEN Growth Inhibition Assay Inhibition of human BEN cell growth in a cell viability assay, IC50 = 5.44777 μM. SANGER
Calu-3 Growth Inhibition Assay Inhibition of human Calu-3 cell growth in a cell viability assay, IC50 = 5.45736 μM. SANGER
8305C Growth Inhibition Assay Inhibition of human 8305C cell growth in a cell viability assay, IC50 = 5.46669 μM. SANGER
ESS-1 Growth Inhibition Assay Inhibition of human ESS-1 cell growth in a cell viability assay, IC50 = 5.47851 μM. SANGER
ME-180 Growth Inhibition Assay Inhibition of human ME-180 cell growth in a cell viability assay, IC50 = 5.48535 μM. SANGER
D-502MG Growth Inhibition Assay Inhibition of human D-502MG cell growth in a cell viability assay, IC50 = 5.49075 μM. SANGER
CP50-MEL-B Growth Inhibition Assay Inhibition of human CP50-MEL-B cell growth in a cell viability assay, IC50 = 5.59584 μM. SANGER
OAW-28 Growth Inhibition Assay Inhibition of human OAW-28 cell growth in a cell viability assay, IC50 = 5.66484 μM. SANGER
SCC-25 Growth Inhibition Assay Inhibition of human SCC-25 cell growth in a cell viability assay, IC50 = 5.66836 μM. SANGER
NCI-H810 Growth Inhibition Assay Inhibition of human NCI-H810 cell growth in a cell viability assay, IC50 = 5.67785 μM. SANGER
no-11 Growth Inhibition Assay Inhibition of human no-11 cell growth in a cell viability assay, IC50 = 5.81096 μM. SANGER
OVCAR-4 Growth Inhibition Assay Inhibition of human OVCAR-4 cell growth in a cell viability assay, IC50 = 6.07487 μM. SANGER
A704 Growth Inhibition Assay Inhibition of human A704 cell growth in a cell viability assay, IC50 = 6.13363 μM. SANGER
GB-1 Growth Inhibition Assay Inhibition of human GB-1 cell growth in a cell viability assay, IC50 = 6.14107 μM. SANGER
NCI-H358 Growth Inhibition Assay Inhibition of human NCI-H358 cell growth in a cell viability assay, IC50 = 6.19117 μM. SANGER
A431 Growth Inhibition Assay Inhibition of human A431 cell growth in a cell viability assay, IC50 = 6.26477 μM. SANGER
SK-MEL-24 Growth Inhibition Assay Inhibition of human SK-MEL-24 cell growth in a cell viability assay, IC50 = 6.2749 μM. SANGER
NB17 Growth Inhibition Assay Inhibition of human NB17 cell growth in a cell viability assay, IC50 = 6.44011 μM. SANGER
BB49-HNC Growth Inhibition Assay Inhibition of human BB49-HNC cell growth in a cell viability assay, IC50 = 6.49529 μM. SANGER
NCI-H1573 Growth Inhibition Assay Inhibition of human NCI-H1573 cell growth in a cell viability assay, IC50 = 6.70803 μM. SANGER
GAK Growth Inhibition Assay Inhibition of human GAK cell growth in a cell viability assay, IC50 = 6.8404 μM. SANGER
CAL-120 Growth Inhibition Assay Inhibition of human CAL-120 cell growth in a cell viability assay, IC50 = 7.07643 μM. SANGER
PANC-08-13 Growth Inhibition Assay Inhibition of human PANC-08-13 cell growth in a cell viability assay, IC50 = 7.78108 μM. SANGER
SW1463 Growth Inhibition Assay Inhibition of human SW1463 cell growth in a cell viability assay, IC50 = 8.01873 μM. SANGER
SW872 Growth Inhibition Assay Inhibition of human SW872 cell growth in a cell viability assay, IC50 = 8.07734 μM. SANGER
HCT-15 Growth Inhibition Assay Inhibition of human HCT-15 cell growth in a cell viability assay, IC50 = 8.12311 μM. SANGER
SH-4 Growth Inhibition Assay Inhibition of human SH-4 cell growth in a cell viability assay, IC50 = 8.14247 μM. SANGER
TE-6 Growth Inhibition Assay Inhibition of human TE-6 cell growth in a cell viability assay, IC50 = 8.24962 μM. SANGER
Capan-2 Growth Inhibition Assay Inhibition of human Capan-2 cell growth in a cell viability assay, IC50 = 8.36036 μM. SANGER
RO82-W-1 Growth Inhibition Assay Inhibition of human RO82-W-1 cell growth in a cell viability assay, IC50 = 8.4861 μM. SANGER
SW948 Growth Inhibition Assay Inhibition of human SW948 cell growth in a cell viability assay, IC50 = 8.56121 μM. SANGER
NB12 Growth Inhibition Assay Inhibition of human NB12 cell growth in a cell viability assay, IC50 = 8.6577 μM. SANGER
NCI-H2342 Growth Inhibition Assay Inhibition of human NCI-H2342 cell growth in a cell viability assay, IC50 = 8.67749 μM. SANGER
PFSK-1 Growth Inhibition Assay Inhibition of human PFSK-1 cell growth in a cell viability assay, IC50 = 8.73766 μM. SANGER
HPAF-II Growth Inhibition Assay Inhibition of human HPAF-II cell growth in a cell viability assay, IC50 = 8.77154 μM. SANGER
MDA-MB-231 Growth Inhibition Assay Inhibition of human MDA-MB-231 cell growth in a cell viability assay, IC50 = 8.82383 μM. SANGER
KNS-81-FD Growth Inhibition Assay Inhibition of human KNS-81-FD cell growth in a cell viability assay, IC50 = 9.19714 μM. SANGER
NCI-H1563 Growth Inhibition Assay Inhibition of human NCI-H1563 cell growth in a cell viability assay, IC50 = 9.21672 μM. SANGER
MEL-HO Growth Inhibition Assay Inhibition of human MEL-HO cell growth in a cell viability assay, IC50 = 9.31744 μM. SANGER
NCI-H2126 Growth Inhibition Assay Inhibition of human NCI-H2126 cell growth in a cell viability assay, IC50 = 9.32815 μM. SANGER
SNB75 Growth Inhibition Assay Inhibition of human SNB75 cell growth in a cell viability assay, IC50 = 9.36079 μM. SANGER
NCI-H1693 Growth Inhibition Assay Inhibition of human NCI-H1693 cell growth in a cell viability assay, IC50 = 9.57931 μM. SANGER
NCI-H460 Growth Inhibition Assay Inhibition of human NCI-H460 cell growth in a cell viability assay, IC50 = 9.6401 μM. SANGER
COLO-824 Growth Inhibition Assay Inhibition of human COLO-824 cell growth in a cell viability assay, IC50 = 9.83259 μM. SANGER
CAL-12T Growth Inhibition Assay Inhibition of human CAL-12T cell growth in a cell viability assay, IC50 = 10.1844 μM. SANGER
KM12 Growth Inhibition Assay Inhibition of human KM12 cell growth in a cell viability assay, IC50 = 10.2778 μM. SANGER
IA-LM Growth Inhibition Assay Inhibition of human IA-LM cell growth in a cell viability assay, IC50 = 10.4447 μM. SANGER
SK-MEL-3 Growth Inhibition Assay Inhibition of human SK-MEL-3 cell growth in a cell viability assay, IC50 = 11.1627 μM. SANGER
LB771-HNC Growth Inhibition Assay Inhibition of human LB771-HNC cell growth in a cell viability assay, IC50 = 11.1986 μM. SANGER
NCI-H2291 Growth Inhibition Assay Inhibition of human NCI-H2291 cell growth in a cell viability assay, IC50 = 11.3553 μM. SANGER
NCI-H1092 Growth Inhibition Assay Inhibition of human NCI-H1092 cell growth in a cell viability assay, IC50 = 11.7291 μM. SANGER
MMAC-SF Growth Inhibition Assay Inhibition of human MMAC-SF cell growth in a cell viability assay, IC50 = 11.9527 μM. SANGER
CP66-MEL Growth Inhibition Assay Inhibition of human CP66-MEL cell growth in a cell viability assay, IC50 = 11.9806 μM. SANGER
LAN-6 Growth Inhibition Assay Inhibition of human LAN-6 cell growth in a cell viability assay, IC50 = 12.4743 μM. SANGER
COLO-684 Growth Inhibition Assay Inhibition of human COLO-684 cell growth in a cell viability assay, IC50 = 12.9893 μM. SANGER
NCI-H720 Growth Inhibition Assay Inhibition of human NCI-H720 cell growth in a cell viability assay, IC50 = 13.1893 μM. SANGER
C32 Growth Inhibition Assay Inhibition of human C32 cell growth in a cell viability assay, IC50 = 13.2745 μM. SANGER
KLE Growth Inhibition Assay Inhibition of human KLE cell growth in a cell viability assay, IC50 = 13.3925 μM. SANGER
NCI-H1648 Growth Inhibition Assay Inhibition of human NCI-H1648 cell growth in a cell viability assay, IC50 = 13.6829 μM. SANGER
SBC-1 Growth Inhibition Assay Inhibition of human SBC-1 cell growth in a cell viability assay, IC50 = 14.2024 μM. SANGER
RVH-421 Growth Inhibition Assay Inhibition of human RVH-421 cell growth in a cell viability assay, IC50 = 14.3302 μM. SANGER
LB373-MEL-D Growth Inhibition Assay Inhibition of human LB373-MEL-D cell growth in a cell viability assay, IC50 = 14.38 μM. SANGER
NCI-H441 Growth Inhibition Assay Inhibition of human NCI-H441 cell growth in a cell viability assay, IC50 = 14.7391 μM. SANGER
ECC10 Growth Inhibition Assay Inhibition of human ECC10 cell growth in a cell viability assay, IC50 = 15.1731 μM. SANGER
SNU-C2B Growth Inhibition Assay Inhibition of human SNU-C2B cell growth in a cell viability assay, IC50 = 15.4643 μM. SANGER
U-266 Growth Inhibition Assay Inhibition of human U-266 cell growth in a cell viability assay, IC50 = 15.5375 μM. SANGER
HOP-62 Growth Inhibition Assay Inhibition of human HOP-62 cell growth in a cell viability assay, IC50 = 16.6013 μM. SANGER
CaR-1 Growth Inhibition Assay Inhibition of human CaR-1 cell growth in a cell viability assay, IC50 = 16.6623 μM. SANGER
LN-405 Growth Inhibition Assay Inhibition of human LN-405 cell growth in a cell viability assay, IC50 = 17.1486 μM. SANGER
DJM-1 Growth Inhibition Assay Inhibition of human DJM-1 cell growth in a cell viability assay, IC50 = 17.17 μM. SANGER
KY821 Growth Inhibition Assay Inhibition of human KY821 cell growth in a cell viability assay, IC50 = 17.2008 μM. SANGER
RMG-I Growth Inhibition Assay Inhibition of human RMG-I cell growth in a cell viability assay, IC50 = 18.5568 μM. SANGER
SBC-5 Growth Inhibition Assay Inhibition of human SBC-5 cell growth in a cell viability assay, IC50 = 19.5065 μM. SANGER
NCI-H1838 Growth Inhibition Assay Inhibition of human NCI-H1838 cell growth in a cell viability assay, IC50 = 19.9055 μM. SANGER
NB6 Growth Inhibition Assay Inhibition of human NB6 cell growth in a cell viability assay, IC50 = 20.2853 μM. SANGER
OVCAR-3 Growth Inhibition Assay Inhibition of human OVCAR-3 cell growth in a cell viability assay, IC50 = 20.3154 μM. SANGER
MKN7 Growth Inhibition Assay Inhibition of human MKN7 cell growth in a cell viability assay, IC50 = 20.3314 μM. SANGER
HCC1569 Growth Inhibition Assay Inhibition of human HCC1569 cell growth in a cell viability assay, IC50 = 21.9995 μM. SANGER
OE19 Growth Inhibition Assay Inhibition of human OE19 cell growth in a cell viability assay, IC50 = 22.4401 μM. SANGER
LU-139 Growth Inhibition Assay Inhibition of human LU-139 cell growth in a cell viability assay, IC50 = 22.4402 μM. SANGER
NB13 Growth Inhibition Assay Inhibition of human NB13 cell growth in a cell viability assay, IC50 = 22.504 μM. SANGER
SW1417 Growth Inhibition Assay Inhibition of human SW1417 cell growth in a cell viability assay, IC50 = 22.5851 μM. SANGER
NCI-H1975 Growth Inhibition Assay Inhibition of human NCI-H1975 cell growth in a cell viability assay, IC50 = 23.8807 μM. SANGER
LCLC-103H Growth Inhibition Assay Inhibition of human LCLC-103H cell growth in a cell viability assay, IC50 = 24.5205 μM. SANGER
HuH-7 Growth Inhibition Assay Inhibition of human HuH-7 cell growth in a cell viability assay, IC50 = 24.6147 μM. SANGER
LU-135 Growth Inhibition Assay Inhibition of human LU-135 cell growth in a cell viability assay, IC50 = 26.5933 μM. SANGER
NCI-H1793 Growth Inhibition Assay Inhibition of human NCI-H1793 cell growth in a cell viability assay, IC50 = 26.6093 μM. SANGER
SK-MEL-30 Growth Inhibition Assay Inhibition of human SK-MEL-30 cell growth in a cell viability assay, IC50 = 27.3999 μM. SANGER
HCC1937 Growth Inhibition Assay Inhibition of human HCC1937 cell growth in a cell viability assay, IC50 = 27.5398 μM. SANGER
639-V Growth Inhibition Assay Inhibition of human 639-V cell growth in a cell viability assay, IC50 = 27.5914 μM. SANGER
HCC1187 Growth Inhibition Assay Inhibition of human HCC1187 cell growth in a cell viability assay, IC50 = 28.6541 μM. SANGER
no-10 Growth Inhibition Assay Inhibition of human no-10 cell growth in a cell viability assay, IC50 = 29.8844 μM. SANGER
HCC1954 Growth Inhibition Assay Inhibition of human HCC1954 cell growth in a cell viability assay, IC50 = 30.3937 μM. SANGER
SW837 Growth Inhibition Assay Inhibition of human SW837 cell growth in a cell viability assay, IC50 = 30.8538 μM. SANGER
CCRF-CEM Growth Inhibition Assay Inhibition of human CCRF-CEM cell growth in a cell viability assay, IC50 = 32.1211 μM. SANGER
CAMA-1 Growth Inhibition Assay Inhibition of human CAMA-1 cell growth in a cell viability assay, IC50 = 32.163 μM. SANGER
T47D Growth Inhibition Assay Inhibition of human T47D cell growth in a cell viability assay, IC50 = 32.1884 μM. SANGER
KNS-42 Growth Inhibition Assay Inhibition of human KNS-42 cell growth in a cell viability assay, IC50 = 32.2443 μM. SANGER
COLO-320-HSR Growth Inhibition Assay Inhibition of human COLO-320-HSR cell growth in a cell viability assay, IC50 = 32.4293 μM. SANGER
UACC-893 Growth Inhibition Assay Inhibition of human UACC-893 cell growth in a cell viability assay, IC50 = 32.6355 μM. SANGER
KALS-1 Growth Inhibition Assay Inhibition of human KALS-1 cell growth in a cell viability assay, IC50 = 33.3928 μM. SANGER
ChaGo-K-1 Growth Inhibition Assay Inhibition of human ChaGo-K-1 cell growth in a cell viability assay, IC50 = 33.7009 μM. SANGER
MFM-223 Growth Inhibition Assay Inhibition of human MFM-223 cell growth in a cell viability assay, IC50 = 34.0243 μM. SANGER
C8166 Growth Inhibition Assay Inhibition of human C8166 cell growth in a cell viability assay, IC50 = 40.3675 μM. SANGER
NCI-H2029 Growth Inhibition Assay Inhibition of human NCI-H2029 cell growth in a cell viability assay, IC50 = 40.9728 μM. SANGER
DMS-79 Growth Inhibition Assay Inhibition of human DMS-79 cell growth in a cell viability assay, IC50 = 41.1583 μM. SANGER
T84 Growth Inhibition Assay Inhibition of human T84 cell growth in a cell viability assay, IC50 = 41.246 μM. SANGER
NCI-H520 Growth Inhibition Assay Inhibition of human NCI-H520 cell growth in a cell viability assay, IC50 = 43.4761 μM. SANGER
COLO-680N Growth Inhibition Assay Inhibition of human COLO-680N cell growth in a cell viability assay, IC50 = 45.2396 μM. SANGER
RH-18 Growth Inhibition Assay Inhibition of human RH-18 cell growth in a cell viability assay, IC50 = 46.3786 μM. SANGER
BT-474 Growth Inhibition Assay Inhibition of human BT-474 cell growth in a cell viability assay, IC50 = 49.4631 μM. SANGER
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Biological Activity

Description Cytarabine is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells. Cytarabine induces autophagy and apoptosis.
Features The 1st of a series of cancer drugs that alters the sugar component of nucleosides.
Targets
DNA synthesis [1]
(CCRF-CEM cells)
16 nM
In vitro
In vitro

Cytarabine (AraC) is phosphorylated into a triphosphate form (Ara-CTP) involving deoxycytidine kinase (dCK), which competes with dCTP for incorporation into DNA, and then blocks DNA synthesis by inhibiting the function of DNA and RNA polymerases. Cytarabine displays a higher growth inhibitory activity towards wild-type CCRF-CEM cells compared to other acute myelogenous leukemia (AML) cells with IC50 of 16 nM. [1] Increasing concentrations of Cytarabine (IC50 of 0.69 μM) results in decreased metabolic activity of sensitive rat leukemic cell line RO/1, and the cell toxity can be highly enhanced by transfection with human wt dCK (IC50 of 0.037 μM) but not the inactive, alternatively spliced dCK forms. [2] Cytarabine apparently induces apoptosis of rat sympathetic neurons at 10 μM, of which 100 μM shows the highest toxicity and kills over 80% of the neurons by 84 hours, involving the release of mitochondrial cytochrome-c and the activation of caspase-3, and the toxicity can be attenuated by p53 knockdown and delayed by bax deletion. [3]
Kinase Assay In Vitro Growth Inhibition Assay
Stock solution of Cytarabine is prepared in absolute ethanol, and serial dilutions of Cytarabine are prepared. CCRF-CEM cells are suspended in RPMI medium supplemented with 10% FBS, 0.1% gentamicin, and 1% sodium pyruvate. The cells are suspended in their respective media to give 10 mL volumes of cell suspension at a final density of 3-6 × 104 cells/mL. Appropriate volumes of Cytarabine solution are transferred to the cell suspensions, and incubation is continued for 72 hours. The cells are spun down and resuspended in fresh Cytarabine -free medium, and final cell counts are determined. The data are analyzed by sigmoidal curve fitting of the cell count versus Cytarabine concentration, and the results are expressed as the IC50 (Cytarabine concentration that inhibits cell growth to 50% of the control value).
Cell Research Cell lines Rat leukemic cell lines RCL/0, RO/1 and K7 and human myelomonocytic leukemic U937
Concentrations ~100 μM
Incubation Time 24, 48 and 72 hours
Method

Cells are incubated in the presence of different concentrations of Cytarabine at 37 °C for 24, 48, and 72 hours. At the time of 20-, 44-, or 68-hour incubation in the presence of Cytarabine, 10 mL of cell proliferation reagent WST-1 solution is added. After 2- and 4-hour incubation with WST-1, cell metabolic activity is assessed with colorimetric changes quantified by measuring the absorbance in a spectrophotometer at 450 nm. And cell division times are calculated from eosin counting in parallel with viability assay
Experimental Result Images Methods Biomarkers Images PMID
Western blot p-mTOR / mTOR / p-S6K / S6K / p-AMPK / AMPK / p-AKT / AKT / p-ERK / ERK 24714637
Growth inhibition assay Cell viability 24714637
In Vivo
In vivo

Cytarabine is highly effective against acute leukaemias, which causes the characteristic G1/S blockage and synchronization, and increases the survival time for leukaemic Brown Norway rats in a weak dose-related fashion indicating that the use of higher dosages of Cytarabine does not contribute to its antileukaemic effectiveness in man. [4] Cytarabine (250 mg/kg) also causes placental growth retardation and increases placental trophoblastic cells apoptosis in the placental labyrinth zone of the pregnant Slc:Wistar rats, which increases from 3 hour after the treatment and peaks at 6 hour before returning to control levels at 48 hour, with remarkably enhanced p53 protein, p53 trancriptional target genes such as p21, cyclinG1 and fas and caspase-3 activity. [5]
Animal Research Animal Models Brown Norway rat with myelocytic leukaemia
Dosages 5 - 1000 mg/kg
Administration Injection i.v.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05697510 Recruiting
Acute Myeloid Leukemia (AML)
Nantes University Hospital
 March 16 2023 Phase 1

Chemical Information & Solubility

Molecular Weight 243.22 Formula

C9H13N3O5
CAS No. 147-94-4 SDF Download Cytarabine SDF
Smiles C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 49 mg/mL ( (201.46 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 49 mg/mL

Ethanol : Insoluble


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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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