Home Cell Cycle CDK inhibitor Avotaciclib trihydrochloride For research use only.

Avotaciclib trihydrochloride

Synonyms: BEY1107 trihydrochloride

Avotaciclib trihydrochloride(BEY1107 trihydrochloride) is a potent and orally active inhibitor of cyclin dependent kinase 1 (CDK1). It can be used for the research of locally advanced or metastatic pancreatic cancer.

Avotaciclib trihydrochloride Chemical Structure

Avotaciclib trihydrochloride Chemical Structure

CAS No. 1983984-01-5

Purity & Quality Control

Batch: E160501 Water]78 mg/mL]false]DMSO]4 mg/mL]false]Ethanol]Insoluble]false Purity: 99.01%
99.01

Avotaciclib trihydrochloride Related Products

Signaling Pathway

CDK Signaling Pathways

CDK Signaling Pathway

Biological Activity

Description Avotaciclib trihydrochloride(BEY1107 trihydrochloride) is a potent and orally active inhibitor of cyclin dependent kinase 1 (CDK1). It can be used for the research of locally advanced or metastatic pancreatic cancer.
Targets
CDK1 [1]

Chemical Information & Solubility

Molecular Weight 390.66 Formula

C13H11N7O.3ClH
CAS No. 1983984-01-5 SDF Download Avotaciclib trihydrochloride SDF
Storage (From the date of receipt)

In vitro
Batch:

Water : 78 mg/mL

DMSO : 4 mg/mL ( (10.23 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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