HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E7431 LEP(116-130)(mouse) LEP(116-130)(mouse) is a synthetic leptin peptide fragment. Dec 19 2024
E7007 Suc-Leu-Leu-Val-Tyr-AMC Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate. Dec 19 2024
E7209 N6-(2-Hydroxyethyl)adenosine N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. Dec 19 2024
E7432 Monoethyl fumarate Monoethyl fumarate is the monoethyl ester form of fumaric acid. Monoethyl fumarate is a kind of effective preservative and polymerization agent for macromolecular material. Dec 19 2024
E7008 ONPG ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity. Dec 19 2024
E7210 Enzalutamide carboxylic acid Enzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist. Dec 19 2024
E7433 C-Phycocyanin C-phycocyanin (C-PC) is a protein pigment which is also widely used as an excellent nutrient supplement for human beings. Dec 19 2024
E5779 4-Azido-L-phenylalanine 4-Azido-L-phenylalanine is an unnatural amino acid, which is used as an effective vibrational reporter of local protein environments. 4-Azido-L-phenylalanine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Dec 19 2024
E7211 Phosphatidylcholines,soya Phosphatidylcholines,soya is a phosphatidylcholine from soybean used in the preparation of liposomes. Phosphatidylcholines,soya can be used as a vehicle in animal agent administration. Dec 19 2024
E4908 Clemizole hydrochloride Clemizole hydrochloride is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. Clemizole hydrochloride is an inhibitor of TRPC5 channel. The IC50 of Clemizole hydrochloride for RNA binding by NS4B is 24 nM, whereas its EC50 for viral replication is 8 μM. Dec 19 2024
E7009 D-Glucose-13C6 D-Glucose-13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose-13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard. Dec 19 2024
E7212 7-Desmethyl-agomelatine 7-Desmethyl-agomelatine is a metabolite of Agomelatine. Agomelatineis a potent agonist at melatonin receptors (MT1 and MT2), and also is an antagonist of 5-HT2C. Dec 19 2024
E7434 Illudin S Illudin S is a potent antitumor sesquiterpene metabolically activated into reactive intermediates that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). It was first isolated from the fungus Clitocybe illudens and disrupts thymidine-dependent DNA synthesis without affecting RNA or protein synthesis. Dec 19 2024
S7468 SR 11302 SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE). Dec 19 2024
E7213 TAPI-1 TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins. TAPI-1 is also a metalloproteinase (MMP) inhibitor. Dec 19 2024
E4737 Potrasertib Potrasertib (IMP7068, WEE1-IN-10) is a potent and selective inhibitor of WEE1 Kinase. It displays antitumor activity and is well-tolerated in patients with advanced solid tumors. Dec 18 2024
S8593 VX-984 VX-984 (M9831) is an orally active, potent, selective, and ATP-competitive inhibitor of DNA-PK. VX-984 effectively suppresses non-homologous end joining (NHEJ) and increases DNA double-strand breaks (DSBs). It enhances the cytotoxic effects of ionizing radiation (IR) in various cancer cell lines, including non-small cell lung cancer (NSCLC) cell lines, in vitro. Additionally, VX-984 reduces DNA-PKcs autophosphorylation. Dec 18 2024
E1462 P62-mediated mitophagy inducer P62-mediated mitophagy inducer (PMI) is a P62-mediated activator of mitophagy that functions independently of parkin recruitment or mitochondrial membrane potential (ΔΨm) collapse. It remains effective even in cells lacking a fully functional PINK1/Parkin pathway. PMI stabilizes Nrf2 and enhances p62 expression, thereby activating mitophagy. Dec 18 2024
E6024 Selumetinib sulfate Selumetinib sulfate (AZD6244 sulfate, ARRY-142886 sulfate) is an oral, non-ATP-competitive inhibitor of MEK1/2, with an IC50 of 14 nmol/L against purified MEK1. It exhibits an anti-tumor effect in the HT-29 xenograft model and is used to treat cancer and inflammation. Dec 18 2024
E4781 OPN expression inhibitor 1 OPN Expression Inhibitor 1 (Compound 11) is a DHA ether derivative containing a 1,2,3-triazole ring that effectively inhibits osteopontin (OPN) expression. It exhibits significant potential as an anticancer agent by specifically targeting OPN, a key factor in breast cancer progression and metastasis. Dec 16 2024