Home Transmembrane Transporters Calcium Channel activator Strontium Ranelate For research use only.

Strontium Ranelate

Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.

Strontium Ranelate Chemical Structure

Strontium Ranelate Chemical Structure

CAS No. 135459-87-9

Purity & Quality Control

Batch: S205001 Water]2 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 99.94%
99.94

Strontium Ranelate Related Products

Signaling Pathway

Calcium Channel Signaling Pathways

Calcium Channel Signaling Pathway

Biological Activity

Description Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.
Targets
Calcium channel [1]
0.5 mM
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01544894 Completed
Postmenopausal Osteoporosis|Compliance
University of Valencia
 September 2009 Phase 4

Chemical Information & Solubility

Molecular Weight 513.49 Formula

C12H6N2O8S.2Sr
CAS No. 135459-87-9 SDF Download Strontium Ranelate SDF
Smiles C(C1=C(SC(=C1C#N)N(CC(=O)[O-])CC(=O)[O-])C(=O)[O-])C(=O)[O-].[Sr+2].[Sr+2]
Storage (From the date of receipt)

In vitro
Batch:

Water : 2 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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