Home Biosimilar Antibodies Apoptosis PD-1/PD-L1 null Sintilimab (anti-PD-1) For research use only.
Not for use in humans.

Sintilimab (anti-PD-1)

Synonyms: IBI 308

Sintilimab (anti-PD-1, IBI 308) is a fully human IgG4 monoclonal antibody that binds to PD-1 on the surface of T-cells, blocks the PD-1/PD-Ligand 1 (PD-L1) pathway, and reactivates T-cells to kill cancer cells.

Sintilimab (anti-PD-1)

Click to purchase the isotype control of Sintilimab (anti-PD-1)

Selleck's Sintilimab (anti-PD-1) has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 5.81 mg/ml Endotoxin Level: <1 EU/mg
99

Choose Selective PD-1/PD-L1 Inhibitors

Name Citation PD-1/PD-L1 interaction PD-1 PD-L1 PD-1/PD-L1 Others
GS-4224 0
INCB086550 0
BMS-1001 0
BMS-1166 5
PD-1/PD-L1 Inhibitor 3 12
BMS-1 11
BMS202 20
CA-170 (AUPM-170)
SR 0987 IL17,RORγt
Spartalizumab (anti-PD-1)
Camrelizumab (anti-PD-1)
AUNP-12
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Sintilimab (anti-PD-1, IBI 308) is a fully human IgG4 monoclonal antibody that binds to PD-1 on the surface of T-cells, blocks the PD-1/PD-Ligand 1 (PD-L1) pathway, and reactivates T-cells to kill cancer cells.

Product Details

CAS No. 2072873-06-2
Isotype Human IgG4, κ
Source CHO cells
Sterility 0.2 μM filtered
Formulation PBS Buffer, PH 7.4
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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