Home Apoptosis ROS chemical - Fungal inhibitor Nerol For research use only.

Nerol

Synonyms: Cis-Geraniol, Neryl alcohol

Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. Nerol has antifungal activity, Nerol can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.

Nerol Chemical Structure

Nerol Chemical Structure

CAS No. 106-25-2

Purity & Quality Control

Nerol Related Products

Biological Activity

Description Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. Nerol has antifungal activity, Nerol can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.
In Vivo
In vivo Nerol possesses a possible anxiolytic effect in mice. In the open field test, groups treated with nerol show a significant decrease in motor activity (number of crossings, rearings and groomings) when compared with vehicle group. In the elevated plus-maze test, nerol groups significantly increase the number of entries and time of permanence in the open arms. In the light-dark test, nerol groups show a significant increase the time of permanence in the room clear when compared with vehicle group. In the rota rod test, the groups treated with nerol do not show modification in time spent and number of falls in the revolving bar when compared with vehicle group[1].
Animal Research Animal Models Swiss male mice Mus musculus (25-30 g; 2-month-old)
Dosages 30, 60 or 90 mg/kg
Administration i.p.

Chemical Information & Solubility

Molecular Weight 154.25 Formula

C10H18O
CAS No. 106-25-2 SDF --
Density 0.876 g/mL at 25 °C
Smiles CC(=CCCC(=CCO)C)C
Storage (From the date of receipt) 2 years -80°C liquid

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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