Nerol

Catalog No.S4970 Batch:S497001

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Technical Data

Formula

C10H18O

Molecular Weight 154.25 CAS No. 106-25-2
Solubility (25°C)* In vitro
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Biological Activity

Description Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. Nerol has antifungal activity, Nerol can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.
In vivo Nerol possesses a possible anxiolytic effect in mice. In the open field test, groups treated with nerol show a significant decrease in motor activity (number of crossings, rearings and groomings) when compared with vehicle group. In the elevated plus-maze test, nerol groups significantly increase the number of entries and time of permanence in the open arms. In the light-dark test, nerol groups show a significant increase the time of permanence in the room clear when compared with vehicle group. In the rota rod test, the groups treated with nerol do not show modification in time spent and number of falls in the revolving bar when compared with vehicle group[1].
Density 0.876 g/mL at 25 °C

Protocol (from reference)

Animal Study:

[1]

  • Animal Models

    Swiss male mice Mus musculus (25-30 g; 2-month-old)

  • Dosages

    30, 60 or 90 mg/kg

  • Administration

    i.p.

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.