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Fungal Products

All (112)
Fungal Inhibitors (106)
New Fungal Products

Catalog No.	Product Name	Information	Product Use Citations
S7418	Cycloheximide	Cycloheximide, an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximide suppresses ferroptosis and inhibits autophagy.Solutions are unstable and should be fresh-prepared.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.	Signal Transduct Target Ther, 2024, 9(1):65 Mol Cancer, 2024, 23(1):143 Mol Cancer, 2024, 23(1):240
S2476	Itraconazole	Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.	Front Cell Infect Microbiol, 2023, 13:1128000 Front Cell Infect Microbiol, 2023, 13:1131641 Front Cell Infect Microbiol, 2022, 12:864912
S1442	Voriconazole	Voriconazole is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol.	Pharmaceutics, 2024, 16(7)897 Front Cell Infect Microbiol, 2023, 13:1131641 Front Cell Infect Microbiol, 2022, 12:864912
S1331	Fluconazole	Fluconazole is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.	Front Cell Infect Microbiol, 2024, 14:1296151 Front Cell Infect Microbiol, 2023, 13:1131641 Nat Commun, 2022, 13(1):1658
S1353	Ketoconazole	Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. Ketoconazole is an androgen biosynthesis inhibitor.	J Med Virol, 2023, 95(6):e28856 J Med Virol, 2023, 95(6):e28856 Cell Death Dis, 2023, 14(1):64
S3073	Caspofungin (MK-0991) Acetate	Caspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.	PLoS Pathog, 2024, 20(9):e1012521 Sci Rep, 2024, 14(1):27500 J Vis Exp, 2024, (206).
S1934	Nystatin	Nystatin(Fungicidin), which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.	Microbiol Spectr, 2023, 10.1128/spectrum.02553-23 Nature, 2022, 603(7899):159-165 Nat Metab, 2022, 4-10:1369-1401
S4286	Anidulafungin	Anidulafungin, an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.	Viruses, 2023, 15(2)452 BMC Med, 2022, 20(1):359 Antiviral Res, 2021, S0166-3542(21)00178-9
S4287	Micafungin Sodium	Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.	Microbiol Spectr, 2024, e0352623. BMC Med, 2022, 20(1):359 Antiviral Res, 2021, S0166-3542(21)00178-9
S3019	Ciclopirox ethanolamine	Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296,Ciclopiroxolamine) is a broad-spectrum antifungal agent working as an iron chelator.	Commun Biol, 2023, 6(1):402 Commun Biol, 2023, 6(1):402 J Clin Invest, 2022, 132(9)e152345
S2058	Tolnaftate	Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.	J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 34(6):1911-1918
S2321	Magnolol	Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-κB activation.	Mol Oncol, 2022, 16(15):2823-2842 Int Immunopharmacol, 2022, 112:109242 Reprod Biol, 2021, 21(4):100567
S1725	Terbinafine	Terbinafine (SF 86-327,TDT 067) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.	Front Oncol, 2023, 13:1111570 Neurooncol Adv, 2022, 4(1):vdac018 J Cell Mol Med, 2020, 25
S1956	Miconazole Nitrate	Miconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.	Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4 Chem Biol Interact, 2021, 343:109498 Biomol Ther (Seoul), 2020, 25
S2528	Ciclopirox	Ciclopirox(HOE 296b, Penlac) is a broad-spectrum antifungal agent working as an iron chelator.	Cell Death Dis, 2021, 12(12):1141 J Transl Med, 2021, 19(1):347 Int J Mol Sci, 2021, 22(15)8299
S3079	Atovaquone	Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.	Cells, 2024, 13(12)1025 iScience, 2024, 27(3):109172 J Cell Biochem, 2022, 10.1002/jcb.30213
S1606	Clotrimazole	Clotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.	PLoS Pathog, 2024, 20(10):e1012601 iScience, 2022, 25(11):105342 Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
S2557	Terbinafine HCl	Terbinafine HCl (KWD 201,KWD 2019,TDT 067 hydrochloride) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.	Cell Rep Med, 2023, S2666-3791(22)00494-3 Oncogene, 2021, 10.1038/s41388-021-01934-y J Cell Mol Med, 2020, 25
S2536	Miconazole	Miconazole (Monistat,R18134) is an imidazole antifungal agent.	Nat Commun, 2024, 15(1):3068 Int J Mol Sci, 2022, 23(22)13809 Chem Biol Interact, 2021, 343:109498
S1676	Amorolfine HCl	Amorolfine HCl(Ro 14-4767 HCl) is an antifungal reagent.	Nat Commun, 2021, 12(1):652 Cell Chem Biol, 2019, 26(4):593-599 Nature, 2018, 560(7718):372-376
S4075	Zinc Pyrithione	Zinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.	Cell Chem Biol, 2021, S2451-9456(21)00213-0 Biol Reprod, 2019, 100(2):468-478 Cell Syst, 2017, 4(6-:600-610
S5080	Neticonazole	Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity.	Nat Commun, 2023, 14(1):6692 Nat Commun, 2023, 14(1):6692 Clin Transl Med, 2022, 12(9):e1037
S1517	Natamycin	Natamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference	Expert Opin Drug Deliv, 2020, 17(3):407-421 BMC Microbiol, 2020, 20(1):275
S2535	Econazole nitrate	Econazole Nitrate (NSC 243115,Spectazole) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.	Nat Commun, 2024, 15(1):8708 Cell Rep Med, 2023, 4(12):101309 Int J Mol Sci, 2022, 23(22)13809
S1910	Tioconazole	Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.	J Mol Cell Biol, 2021, mjab059 Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S4120	Sulconazole Nitrate	Sulconazole Nitrate(Exelderm,RS 44872) is an imidazole derivative with broad-spectrum antifungal activity.	Int J Mol Sci, 2022, 23(22)13809 Sci Adv, 2021, 7(36):eabf6033
S4601	Clioquinol	Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.	Cancer Lett, 2024, 588:216797 Mol Oncol, 2021, 10.1002/1878-0261.13079 FASEB J, 2019, 10.1096/fj.201802603RR
S5373	Pseudolaric Acid B	Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.	Toxicology, 2023, 493:153556 Eur J Pharmacol, 2020, 876:173064
S1666	Flucytosine (5-Fluorocytosine)	Flucytosine (5-Fluorocytosine) is an antifungal drug with IC50 of 0.93 μM in C. albicans.	Sci Adv, 2021, 7(27)eabh3032
S1854	Bifonazole	Bifonazole (Bay h 4502,(±)-bifonazole) is a substituted imidazole antifungal agent.	Nature, 2018, 560(7718):372-376
S3161	Sertaconazole nitrate	Sertaconazole nitrate (FI-7045,FI7056) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.	Int J Mol Sci, 2022, 23(22)13809
S5359	Butoconazole	Butoconazole is an imidazole antifungal used in gynecology.	Arch Biochem Biophys, 2024, 754:109958 Nature, 2018, 560(7718):372-376
S8095	Tubercidin	Tubercidin (7-deaza-adenosine), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.	Mol Cell, 2020, 80(6):1104-1122.e9
S4584	Butylparaben	Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) is a chemical compound commonly used as an antifungal preservative in cosmetic products.	Environ Toxicol, 2018, 33(4):436-445
S4178	Climbazole	Climbazole(BAY-e 6975) is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits.	Sci Adv, 2022, 8(49):eadd2191
S3646	Thimerosal	Thimerosal (Thiomersalate, Mercurothiolate) is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks. This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.	EMBO J, 2024, 10.1038/s44318-024-00217-y J Invest Dermatol, 2024, S0022-202X(23)03210-4 Cell Chem Biol, 2021, S2451-9456(21)00442-6
S4187	Salicylanilide	Salicylanilides (WR10019,2-Hydroxybenzanilide) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.	Hum Mol Genet, 2020, ddaa244
S9057	Sinigrin	Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.	J Invest Dermatol, 2018, 138(12):2644-2652
S5033	Terconazole	Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol,R42470) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.	bioRxiv, 2020, 2020/9/20.4.7.30734
S5174	Kojic acid	Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.	Int J Mol Sci, 2017, 18(9)
S3722	Isavuconazole	Isavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis.	Sci Rep, 2024, 14(1):27500 J Pharm Sci, 2023, 10.1016/j.xphs.2023.11.005
S5083	Lentinan	Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.	Cell Commun Signal, 2024, 22(1):376 Iran J Basic Med Sci, 2023, 26(7):836-842
S4878	Neticonazole Hydrochloride	Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.	Toxins (Basel), 2024, 16(9)380 Clin Transl Med, 2022, 12(9):e1037
S5512	Juglone	Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.Solutions are unstable and should be fresh-prepared.	Chin Med, 2024, 19(1):52 Nat Commun, 2019, 10(1):4013
S1997	Liranaftate	Liranaftate (M-732,Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities.	Cell Rep, 2024, 43(4):114094
S2031	Fenticonazole Nitrate	Fenticonazole Nitrate(Lomexin,REC 15-1476,Falvin) is an azole antifungal agent.
S3154	Butenafine HCl	Butenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
S3156	Naftifine HCl	Naftifine(AW 105-843) is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.	Clin Transl Med, 2024, 14(2):e1586 Arch Biochem Biophys, 2024, 754:109958
S1833	Butoconazole nitrate	Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).
S4806	Potassium 1-Naphthaleneacetate	Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
E3040	Stemonae Extract	Stemonae Extract is extracted from Radix Stemonae, has been widely used as an oral anti-tussive agent in traditional Chinese medicine (TCM) for thousands of years with pharmacological effects as anti-tussive, anti-tuberculous, anti-bacterial, anti-fungal and anti-helminthic.
S9200	Pneumocandin B0	Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S0917	Allosecurinin	Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from M.indica and M.discoidea with antifungal activity.
S6254	Hydrocinnamic acid	Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite.
S4581	Triacetin	Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent.
S5213	Piroctone Olamine	Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
S5553	Kasugamycin hydrochloride	Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S0938	Sakuranetin	Sakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties.
E3071	Malaytea Scurfpea Extract	Malaytea Scurfpea Extract is extracted from Psoralea corylifolia L., which has antifungal activity and acts as a defence against pathogens.
S5944	Butenafine	Butenafine is a synthetic benzylamine antifungal agent.
S3966	Nifuratel	Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
S3307	Galangin 3-methyl ether	Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin), isolated from Lychnophora markgravii aerial parts, shows strong antibacterial and antifungal effects.
S4970	Nerol	Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. Nerol has antifungal activity, Nerol can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.
S4862	Squalene	Squalene (Spinacene, Supraene, trans-Squalene), a naturally occurring substance found in plants, animals and humans, is a component of some adjuvants that is added to vaccines to enhance the immune response.	Nature, 2024, 626(7998):411-418.
S3829	Isoalantolactone	Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia. Isoalantolactone is an apoptosis inducer, which also acts as an alkylating agent.
S0770	Camalexin	Camalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities.
S6118	Terpinen-4-ol	Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.,
S4996	Tavaborole (AN-2690)	Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.
S5271	Suloctidil	Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.
E3725	Sapindus saponaria Linnaeus nutshell Extract (40%)	Sapindus Saponaria Linnaeus Nutshell Extract (40%) is derived from Sapindus saponaria L., which has antifungal properties.
E3726	Sapindus saponaria Linnaeus nutshell Extract (70%)	Sapindus Saponaria Linnaeus Nutshell Extract (70%) is derived from Sapindus saponaria L., which has antifungal properties.
S4755	lanosterol	Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol.	Commun Biol, 2023, 6(1):1108
S3532	AN-2718	AN-2718, an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism.
S3778	Patchouli alcohol	Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S4963	Purpurin	Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin) is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. It exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Purpurin strongly inhibits the activities of CYP1A1, CYP1A2 and CYP1B1.
S6270	2-Aminoisobutyric acid	2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH) is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin.
S4258	Luliconazole	Luliconazole(NND 502) is a broad-spectrum antifungal drug.	Arch Biochem Biophys, 2024, 754:109958
S9350	Ethyl 4-Methoxycinnamate	Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S2534	Isoconazole nitrate	Isoconazole nitrate (Travogen,Adestan G 100, R 15454) is an azole antifungal reagent.
S5704	Myclobutanil	Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S3705	Chlorobutanol	Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran\|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.
S1991	iKIX1	iKIX1 is an antifungal agent and resensitizes drug-resistant Candida glabrata to azole antifungals in vitro, which blocks the interaction between the CgGal11A KIX domain and theCgPdr1 activation domain (AD), the IC50 and Ki values are 190.2 μM and 18 μM, respectively.
S3860	Allicin	Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects., Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S9072	Sweroside	Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S6408	Hexetidine	Hexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity.
S5025	Efinaconazole	Efinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.
S3588	Hexylene glycol	Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties.
S3595	D-Gluconic acid	D-Gluconic acid is an antifungal agent.
S9413	Yangonin	Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
E3706	Cortex pseudolaricis Extract	Cortex Pseudolaricis Extract is derived from the root bark of Pseudolarix amabilis Rehder, of which some constituents possess biological activity such as antifungal activity, anticancer activity, and peroxisome proliferator-activated receptor activity.
S5724	Dichlorophen	Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.	Nat Commun, 2024, 15(1):8708
S5829	Monomyristin	Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate), a monoacylglyceride, shows high antibacterial and antifungal activities.
S6451	Salifungin	Salifungin (Multifungin, Bromosalicylchloranilide) is an antifungal and may cause allergic contact dermatitis in some individuals.
S5541	Dimetridazole	Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
S3979	Zinc Undecylenate	Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
S5086	p-Anisaldehyde	p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
S6467	Fosfluconazole	Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
S9444	Tomatine	Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S4525	Ethylparaben	Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
S4781	Xanthoxyline	Xanthoxylin (Brevifolin), isolated from Zanthoxylum piperitum (Japanese pepper tree) and Sapium sebiferum (Chinese tallowtree), is a cytotoxic and fungicidal compound with the characteristics of a typical phytoalexin.
S5845	Chalcone	Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones with antibacterial, antifungal, antitumor and anti-inflammatory properties.
S4793	Cedryl acetate	Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
E3772	Eyebright Extract	Eyebright Extract is extracted from Herba Euphrasiae (Scrophulariaceae), which includes anti-inflammatory, antioxidant, antimicrobial, anticancer, antifungal, antiviral, hypotensive, hapatoprotector, anti-epileptic, and anti-catarrhal activities.
E3488	Fucus vesiculosis Extract	Fucus Vesiculosis Extract is extrcated from Fucus vesiculosus, which has antifungal properties.
S4516	(+)-Camphor	Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1 and TRPV3.
S4843	Potassium acetate	Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
E4002	Potassium D-gluconate	Potassium D-gluconate(Potassium Gluconate) is an orally active carboxylic acid by the oxidation with antiseptic and chelating properties.
S3910	4',7-Dimethoxyisoflavone	4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S4559	Cloxiquine	Cloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug.
S3985	Methyl 4-hydroxybenzoate	Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.
S0491	Manogepix (E1210)	Manogepix (E1210, MGX, APX001A) is a broad-spectrum and orally active antifungal agent that inhibits Gwt1/Gwt1p (GPI-anchored wall transfer protein 1), a protein that plays an important role in fungal cell wall integrity.	Nat Commun, 2024, 15(1):9194 Antimicrob Agents Chemother, 2024, 68(11):e0080324
S3990	Trans-Anethole	Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.
S7418	Cycloheximide	Cycloheximide, an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximide suppresses ferroptosis and inhibits autophagy.Solutions are unstable and should be fresh-prepared.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.	Signal Transduct Target Ther, 2024, 9(1):65 Mol Cancer, 2024, 23(1):143 Mol Cancer, 2024, 23(1):240
S2476	Itraconazole	Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.	Front Cell Infect Microbiol, 2023, 13:1128000 Front Cell Infect Microbiol, 2023, 13:1131641 Front Cell Infect Microbiol, 2022, 12:864912
S1331	Fluconazole	Fluconazole is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.	Front Cell Infect Microbiol, 2024, 14:1296151 Front Cell Infect Microbiol, 2023, 13:1131641 Nat Commun, 2022, 13(1):1658
S1353	Ketoconazole	Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. Ketoconazole is an androgen biosynthesis inhibitor.	J Med Virol, 2023, 95(6):e28856 J Med Virol, 2023, 95(6):e28856 Cell Death Dis, 2023, 14(1):64
S3073	Caspofungin (MK-0991) Acetate	Caspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.	PLoS Pathog, 2024, 20(9):e1012521 Sci Rep, 2024, 14(1):27500 J Vis Exp, 2024, (206).
S1934	Nystatin	Nystatin(Fungicidin), which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.	Microbiol Spectr, 2023, 10.1128/spectrum.02553-23 Nature, 2022, 603(7899):159-165 Nat Metab, 2022, 4-10:1369-1401
S4286	Anidulafungin	Anidulafungin, an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.	Viruses, 2023, 15(2)452 BMC Med, 2022, 20(1):359 Antiviral Res, 2021, S0166-3542(21)00178-9
S4287	Micafungin Sodium	Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.	Microbiol Spectr, 2024, e0352623. BMC Med, 2022, 20(1):359 Antiviral Res, 2021, S0166-3542(21)00178-9
S3019	Ciclopirox ethanolamine	Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296,Ciclopiroxolamine) is a broad-spectrum antifungal agent working as an iron chelator.	Commun Biol, 2023, 6(1):402 Commun Biol, 2023, 6(1):402 J Clin Invest, 2022, 132(9)e152345
S2058	Tolnaftate	Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.	J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 34(6):1911-1918
S2321	Magnolol	Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-κB activation.	Mol Oncol, 2022, 16(15):2823-2842 Int Immunopharmacol, 2022, 112:109242 Reprod Biol, 2021, 21(4):100567
S1725	Terbinafine	Terbinafine (SF 86-327,TDT 067) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.	Front Oncol, 2023, 13:1111570 Neurooncol Adv, 2022, 4(1):vdac018 J Cell Mol Med, 2020, 25
S1956	Miconazole Nitrate	Miconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.	Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4 Chem Biol Interact, 2021, 343:109498 Biomol Ther (Seoul), 2020, 25
S2528	Ciclopirox	Ciclopirox(HOE 296b, Penlac) is a broad-spectrum antifungal agent working as an iron chelator.	Cell Death Dis, 2021, 12(12):1141 J Transl Med, 2021, 19(1):347 Int J Mol Sci, 2021, 22(15)8299
S3079	Atovaquone	Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.	Cells, 2024, 13(12)1025 iScience, 2024, 27(3):109172 J Cell Biochem, 2022, 10.1002/jcb.30213
S1606	Clotrimazole	Clotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.	PLoS Pathog, 2024, 20(10):e1012601 iScience, 2022, 25(11):105342 Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
S2557	Terbinafine HCl	Terbinafine HCl (KWD 201,KWD 2019,TDT 067 hydrochloride) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.	Cell Rep Med, 2023, S2666-3791(22)00494-3 Oncogene, 2021, 10.1038/s41388-021-01934-y J Cell Mol Med, 2020, 25
S2536	Miconazole	Miconazole (Monistat,R18134) is an imidazole antifungal agent.	Nat Commun, 2024, 15(1):3068 Int J Mol Sci, 2022, 23(22)13809 Chem Biol Interact, 2021, 343:109498
S1676	Amorolfine HCl	Amorolfine HCl(Ro 14-4767 HCl) is an antifungal reagent.	Nat Commun, 2021, 12(1):652 Cell Chem Biol, 2019, 26(4):593-599 Nature, 2018, 560(7718):372-376
S4075	Zinc Pyrithione	Zinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.	Cell Chem Biol, 2021, S2451-9456(21)00213-0 Biol Reprod, 2019, 100(2):468-478 Cell Syst, 2017, 4(6-:600-610
S5080	Neticonazole	Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity.	Nat Commun, 2023, 14(1):6692 Nat Commun, 2023, 14(1):6692 Clin Transl Med, 2022, 12(9):e1037
S1517	Natamycin	Natamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference	Expert Opin Drug Deliv, 2020, 17(3):407-421 BMC Microbiol, 2020, 20(1):275
S2535	Econazole nitrate	Econazole Nitrate (NSC 243115,Spectazole) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.	Nat Commun, 2024, 15(1):8708 Cell Rep Med, 2023, 4(12):101309 Int J Mol Sci, 2022, 23(22)13809
S1910	Tioconazole	Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.	J Mol Cell Biol, 2021, mjab059 Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S4120	Sulconazole Nitrate	Sulconazole Nitrate(Exelderm,RS 44872) is an imidazole derivative with broad-spectrum antifungal activity.	Int J Mol Sci, 2022, 23(22)13809 Sci Adv, 2021, 7(36):eabf6033
S4601	Clioquinol	Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.	Cancer Lett, 2024, 588:216797 Mol Oncol, 2021, 10.1002/1878-0261.13079 FASEB J, 2019, 10.1096/fj.201802603RR
S5373	Pseudolaric Acid B	Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.	Toxicology, 2023, 493:153556 Eur J Pharmacol, 2020, 876:173064
S1666	Flucytosine (5-Fluorocytosine)	Flucytosine (5-Fluorocytosine) is an antifungal drug with IC50 of 0.93 μM in C. albicans.	Sci Adv, 2021, 7(27)eabh3032
S1854	Bifonazole	Bifonazole (Bay h 4502,(±)-bifonazole) is a substituted imidazole antifungal agent.	Nature, 2018, 560(7718):372-376
S3161	Sertaconazole nitrate	Sertaconazole nitrate (FI-7045,FI7056) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.	Int J Mol Sci, 2022, 23(22)13809
S5359	Butoconazole	Butoconazole is an imidazole antifungal used in gynecology.	Arch Biochem Biophys, 2024, 754:109958 Nature, 2018, 560(7718):372-376
S8095	Tubercidin	Tubercidin (7-deaza-adenosine), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.	Mol Cell, 2020, 80(6):1104-1122.e9
S4584	Butylparaben	Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) is a chemical compound commonly used as an antifungal preservative in cosmetic products.	Environ Toxicol, 2018, 33(4):436-445
S4178	Climbazole	Climbazole(BAY-e 6975) is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits.	Sci Adv, 2022, 8(49):eadd2191
S3646	Thimerosal	Thimerosal (Thiomersalate, Mercurothiolate) is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks. This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.	EMBO J, 2024, 10.1038/s44318-024-00217-y J Invest Dermatol, 2024, S0022-202X(23)03210-4 Cell Chem Biol, 2021, S2451-9456(21)00442-6
S4187	Salicylanilide	Salicylanilides (WR10019,2-Hydroxybenzanilide) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.	Hum Mol Genet, 2020, ddaa244
S9057	Sinigrin	Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.	J Invest Dermatol, 2018, 138(12):2644-2652
S5033	Terconazole	Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol,R42470) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.	bioRxiv, 2020, 2020/9/20.4.7.30734
S3722	Isavuconazole	Isavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis.	Sci Rep, 2024, 14(1):27500 J Pharm Sci, 2023, 10.1016/j.xphs.2023.11.005
S4878	Neticonazole Hydrochloride	Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.	Toxins (Basel), 2024, 16(9)380 Clin Transl Med, 2022, 12(9):e1037
S5512	Juglone	Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.Solutions are unstable and should be fresh-prepared.	Chin Med, 2024, 19(1):52 Nat Commun, 2019, 10(1):4013
S1997	Liranaftate	Liranaftate (M-732,Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities.	Cell Rep, 2024, 43(4):114094
S2031	Fenticonazole Nitrate	Fenticonazole Nitrate(Lomexin,REC 15-1476,Falvin) is an azole antifungal agent.
S3154	Butenafine HCl	Butenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
S3156	Naftifine HCl	Naftifine(AW 105-843) is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.	Clin Transl Med, 2024, 14(2):e1586 Arch Biochem Biophys, 2024, 754:109958
S1833	Butoconazole nitrate	Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).
S4806	Potassium 1-Naphthaleneacetate	Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
E3040	Stemonae Extract	Stemonae Extract is extracted from Radix Stemonae, has been widely used as an oral anti-tussive agent in traditional Chinese medicine (TCM) for thousands of years with pharmacological effects as anti-tussive, anti-tuberculous, anti-bacterial, anti-fungal and anti-helminthic.
S9200	Pneumocandin B0	Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S0917	Allosecurinin	Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from M.indica and M.discoidea with antifungal activity.
S6254	Hydrocinnamic acid	Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite.
S4581	Triacetin	Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent.
S5213	Piroctone Olamine	Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
S5553	Kasugamycin hydrochloride	Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S0938	Sakuranetin	Sakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties.
E3071	Malaytea Scurfpea Extract	Malaytea Scurfpea Extract is extracted from Psoralea corylifolia L., which has antifungal activity and acts as a defence against pathogens.
S5944	Butenafine	Butenafine is a synthetic benzylamine antifungal agent.
S3966	Nifuratel	Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
S3307	Galangin 3-methyl ether	Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin), isolated from Lychnophora markgravii aerial parts, shows strong antibacterial and antifungal effects.
S4970	Nerol	Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. Nerol has antifungal activity, Nerol can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.
S3829	Isoalantolactone	Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia. Isoalantolactone is an apoptosis inducer, which also acts as an alkylating agent.
S0770	Camalexin	Camalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities.
S6118	Terpinen-4-ol	Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.,
S4996	Tavaborole (AN-2690)	Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.
S5271	Suloctidil	Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.
E3725	Sapindus saponaria Linnaeus nutshell Extract (40%)	Sapindus Saponaria Linnaeus Nutshell Extract (40%) is derived from Sapindus saponaria L., which has antifungal properties.
E3726	Sapindus saponaria Linnaeus nutshell Extract (70%)	Sapindus Saponaria Linnaeus Nutshell Extract (70%) is derived from Sapindus saponaria L., which has antifungal properties.
S4755	lanosterol	Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol.	Commun Biol, 2023, 6(1):1108
S3532	AN-2718	AN-2718, an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism.
S3778	Patchouli alcohol	Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S4963	Purpurin	Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin) is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. It exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Purpurin strongly inhibits the activities of CYP1A1, CYP1A2 and CYP1B1.
S6270	2-Aminoisobutyric acid	2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH) is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin.
S4258	Luliconazole	Luliconazole(NND 502) is a broad-spectrum antifungal drug.	Arch Biochem Biophys, 2024, 754:109958
S9350	Ethyl 4-Methoxycinnamate	Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S2534	Isoconazole nitrate	Isoconazole nitrate (Travogen,Adestan G 100, R 15454) is an azole antifungal reagent.
S5704	Myclobutanil	Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S3705	Chlorobutanol	Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran\|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.
S1991	iKIX1	iKIX1 is an antifungal agent and resensitizes drug-resistant Candida glabrata to azole antifungals in vitro, which blocks the interaction between the CgGal11A KIX domain and theCgPdr1 activation domain (AD), the IC50 and Ki values are 190.2 μM and 18 μM, respectively.
S3860	Allicin	Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects., Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S9072	Sweroside	Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S6408	Hexetidine	Hexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity.
S5025	Efinaconazole	Efinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.
S3588	Hexylene glycol	Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties.
S3595	D-Gluconic acid	D-Gluconic acid is an antifungal agent.
S9413	Yangonin	Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
E3706	Cortex pseudolaricis Extract	Cortex Pseudolaricis Extract is derived from the root bark of Pseudolarix amabilis Rehder, of which some constituents possess biological activity such as antifungal activity, anticancer activity, and peroxisome proliferator-activated receptor activity.
S5724	Dichlorophen	Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.	Nat Commun, 2024, 15(1):8708
S5829	Monomyristin	Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate), a monoacylglyceride, shows high antibacterial and antifungal activities.
S6451	Salifungin	Salifungin (Multifungin, Bromosalicylchloranilide) is an antifungal and may cause allergic contact dermatitis in some individuals.
S5541	Dimetridazole	Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
S3979	Zinc Undecylenate	Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
S5086	p-Anisaldehyde	p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
S6467	Fosfluconazole	Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
S9444	Tomatine	Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S4525	Ethylparaben	Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
S5845	Chalcone	Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones with antibacterial, antifungal, antitumor and anti-inflammatory properties.
S4793	Cedryl acetate	Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
E3772	Eyebright Extract	Eyebright Extract is extracted from Herba Euphrasiae (Scrophulariaceae), which includes anti-inflammatory, antioxidant, antimicrobial, anticancer, antifungal, antiviral, hypotensive, hapatoprotector, anti-epileptic, and anti-catarrhal activities.
E3488	Fucus vesiculosis Extract	Fucus Vesiculosis Extract is extrcated from Fucus vesiculosus, which has antifungal properties.
S4516	(+)-Camphor	Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1 and TRPV3.
S4843	Potassium acetate	Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
S3910	4',7-Dimethoxyisoflavone	4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S4559	Cloxiquine	Cloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug.
S3985	Methyl 4-hydroxybenzoate	Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.
S0491	Manogepix (E1210)	Manogepix (E1210, MGX, APX001A) is a broad-spectrum and orally active antifungal agent that inhibits Gwt1/Gwt1p (GPI-anchored wall transfer protein 1), a protein that plays an important role in fungal cell wall integrity.	Nat Commun, 2024, 15(1):9194 Antimicrob Agents Chemother, 2024, 68(11):e0080324
S3990	Trans-Anethole	Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.

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