Parasite

Parasite Products

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  • Parasite Inhibitors (56)
  • New Parasite Products
Catalog No. Product Name Information Product Use Citations Product Validations
S7379 E-64 E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite.
Cancer Cell, 2022, 40(9):1044-1059.e8
Molecules, 2022, 27(6)1755
Nat Nanotechnol, 2021, 10.1038/s41565-021-00988-z
S5816 Pyrvinium pamoate Pyrvinium pamoate(Pyrvinium embonate) is an anthelmintic effective for pinworms.
Endocrine, 2024, 10.1007/s12020-024-03887-0
Adv Healthc Mater, 2023, e2300591.
Front Cell Infect Microbiol, 2022, 12:1074903
S4610 Mebendazole Mebendazole is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake.
Cancers (Basel), 2022, 14(17)4196
Molecules, 2022, 27(23)8127
Adv Biol (Weinh), 2022, 6(8):e2200030
S3079 Atovaquone Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
Cells, 2024, 13(12)1025
iScience, 2024, 27(3):109172
J Cell Biochem, 2022, 10.1002/jcb.30213
S5948 Amodiaquine Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria.
Molecules, 2024, 29(6)1363
Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9
bioRxiv, 2020, 10.1101/2020.04.13.039917
S4104 Diminazene Aceturate Diminazene(Diminazene diaceturate) is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
Cell, 2024, 187(15):4095-4112.e21
Cell, 2024, 187(15):4095-4112.e21
Bone Joint Res, 2024, 13(3):110-123
S1837 Flubendazole Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.
Nat Commun, 2024, 15(1):4513
Sci Rep, 2020, 10(1):13124
RSC Advances, 2018, 10.1039/C7RA12259D
S1691 Praziquantel Praziquantel is an anthelmintic effective against flatworms.
Parasitology, 2020, 1-11
PLoS Negl Trop Dis, 2015, 9(3):e0003593
S2028 Diclazuril Diclazuril(R-64433) is an anti-coccidial drug.
Hum Mol Genet, 2020, ddaa244
S1851 Oxibendazole Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
Oncol Lett, 2018, 15(2):2218-2226
S1830 Oxfendazole Oxfendazole (RS-8858,Fenbendazole sulfoxide) is a broad spectrum benzimidazole anthelmintic.
Mol Med Rep, 2019, 19(4):2921-2926
E3814 Phyllanthus Urinaria Extract Phyllanthus Urinaria Extract is extracted from Phyllanthus urinaria (L.), which is used to treat jaundice, diabetes, malaria, and liver diseases.
Phytomedicine, 2024, 10.1016/j.phymed.2023.155091
S3741 Benznidazole Benznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.
Int J Mol Sci, 2024, 25(8)4413
Microorganisms, 2022, 10(7)1421
S4422 Nitenpyram Nitenpyram(Bestguard,Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.
Proc Natl Acad Sci U S A, 2020, 117(21):11321-11327
S5345 Nerolidol Nerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.
Int Immunopharmacol, 2020, 80:106118
S4068 Tinidazole Tinidazole (CP12574) is an anti-parasitic drug.
Int J Mol Sci, 2024, 25(8)4413
Microorganisms, 2022, 10(7)1421
S3889 Arteether Arteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite.
ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S5094 Maduramycin Ammonium Maduramicin, which could be isolated from the actinomycete Actinomadura rubra, is an antiprotozoal agent used in veterinary medicine to prevent coccidiosis.
Cancers (Basel), 2019, 11(6)
S2468 Fenbendazole Fenbendazole(Fenbendazol,Phenbendasol) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
S2501 Pyrantel Pamoate Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.
S4141 Dinitolmide Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug.
S4044 Toltrazuril Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
S4094 Tetramisole HCl Tetramisole(R-829,(±)-Tetramisole hydrochloride) is a mixture of dextro- and levo isomers used as an anthelmintic.
E3040 Stemonae Extract Stemonae Extract is extracted from Radix Stemonae, has been widely used as an oral anti-tussive agent in traditional Chinese medicine (TCM) for thousands of years with pharmacological effects as anti-tussive, anti-tuberculous, anti-bacterial, anti-fungal and anti-helminthic.
S3999 α-santonin α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent.
S4866 Nicarbazin Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug.
E3182 Carica Papaya Fruit Extract Carica Papaya Fruit Extract is extracted from the fruit of Carica Papaya, which has proven antihelminthic and anti-amoebic activities.
E3085 Dichroae Radix Extract Dichroae Radix Extract is drawed from Dichroae radix, exhibits good clinical efficacy in treatments as an antimalarial, expectorant or antifebrile agent in Chinese medicine, and it also has an anticoccidial effect in chickens infected by coccidiosis when used alone or as the main herb to formulate a complex.
E3194 Torreyae Semen Extract Torreyae Semen Extract is extracted from the seed of Torreya grandis, which is used in treating intestinal parasites.
S4876 Robenidine Hydrochloride Robenidine Hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) is an anticoccidial agent mainly for poultry.
E3101 Toosendan Fructus Extract Toosendan Fructus Extract is extracted from Fructus Meliae Toosendan, which has potent anticoccidial effects and also acts as an alternative anticoccidial agent for avian coccidiosis control.
E3111 Tribulus Terrestris Extract Tribulus Terrestris Extract is extracted from Tribulus Terrestris, which has anti-inflammatory, analgesic, antispasmodic, anticancer, antibacterial, anthelmintic, larvicidal, and anticariogenic activities.
S4145 Decoquinate Decoquinate is a coccidiostat.
S4599 Benzyl benzoate Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
S0081 DDD107498 DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.
S4167 Cyromazine Cyromazine(Cyromazin,CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide.
S5722 Oxantel Pamoate Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting.
E3355 Cinchona Extract Cinchona Extract is extracted from Cinchona, which is used in the treatment of Malaria.
S4898 Sulfalozine sodium Sulfalozine sodium (Sulfaclozine sodium, Sulfachlopryrazine sodium) is an antiprotozoal useful in coccidiosis research.
S4882 Resorantel Resorantel is a safe, hydroxybenzanilide cestocide highly effective against Moniezia and Thysaniezia spp. and moderately effective against Paramphistomum spp.
S5017 Oxyclozanide Oxyclozanide (Oxiclozanidum, Zanil, Oxyclozanid, Zanilox) is a salicylanilide anthelmintic and mitochondrial uncoupling anthelmintic drug approved for veterinary use.
S3713 Moxidectin Moxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari.
S3707 Ethopabate Ethopabate (ETP, Ethyl pabate) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens.
S5055 Milbemycin Oxime Milbemycin Oxime is a broad spectrum anti-parasitic drug that is active against worms (anthelmintic) and mites (miticide).
S5031 Sulfaquinoxaline sodium Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na) is the sodium salt of sulfaquinoxaline, which is often used as a drug to prevent coccidiosis in poultry, swine, and sheep by inhibiting the synthesis of nucleic acids and proteins in microorganisms.
E3145 Kochiae Fructus Extract Kochiae Fructus Extract is obtained from dried fruit of Kochia scoparia (L.) Schrad., broom cypress fruit), has attracted considerable attention for its pharmacological activities, including antiinflammation, antidiabetics, insecticide, antianaphylaxis, antipruritic and anti-rheumatoid arthritis.
S3591 Eprinomectin Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity.
E3165 Rabdosiae Rubescentis Herba Extract Rabdosiae Rubescentis Herba Extract is drawed from the dried aerial part of genus Rabdosia rubescens (Hemsl.) Hara of the Lamiaceae family, which possesses several biological activities, such as anti-bacteria, anti-parasites, anti-inflammation, and anticancer.
S5093 Rafoxanide Rafoxanide (Disalan, Ranide, Flukanide, Bovanide) is a salicylanilide used as an anthelmintic, being effective treatment for the control of fluke infections in animals.
S5092 Febantel Febantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) is a prodrug that is metabolized to fenbendazole and oxfendazole, which are undoubtedly the active parasiticides.
S5557 Aklomide Aklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry.
S4443 Piperazine adipate Piperazine adipate is a broad spectrum anthelmintic agent that inhibits malate oxidation in Ascaridia galli and Heterakis gallinae.
S0467 Emodepside Emodepside (QHT06, BAY 44-4400, PF 1022-221), a semisynthetic derivative of PF1022A, is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Emodepside activates Ca-dependent SLO-1-like K channels.
S4389 Bephenium Hydroxynaphthoate Bephenium(NSC 759245) is an activator of B-type Acetylcholine receptor (AChR). Bephenium selectively activates the Hco-L-AChR1 subtype made of Hco-UNC-29.1, Hco-UNC-38, Hco-UNC-63, Hco-ACR-8 subunits. Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.
S4564 Diethylcarbamazine citrate Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.
S4999 Avermectin B1 Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.
Cancer Chemother Pharmacol, 2024, 94(4):599-613
S1265 SQ109 SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for LLC-MK2 culture-derived trypomastigotes of 50±8 nM, targets MmpL3 (mycobacterial membrane protein large 3) in Mycobacterium tuberculosis.
S5247 Selamectin Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.
S7379 E-64 E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite.
Cancer Cell, 2022, 40(9):1044-1059.e8
Molecules, 2022, 27(6)1755
Nat Nanotechnol, 2021, 10.1038/s41565-021-00988-z
S5816 Pyrvinium pamoate Pyrvinium pamoate(Pyrvinium embonate) is an anthelmintic effective for pinworms.
Endocrine, 2024, 10.1007/s12020-024-03887-0
Adv Healthc Mater, 2023, e2300591.
Front Cell Infect Microbiol, 2022, 12:1074903
S4610 Mebendazole Mebendazole is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake.
Cancers (Basel), 2022, 14(17)4196
Molecules, 2022, 27(23)8127
Adv Biol (Weinh), 2022, 6(8):e2200030
S3079 Atovaquone Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
Cells, 2024, 13(12)1025
iScience, 2024, 27(3):109172
J Cell Biochem, 2022, 10.1002/jcb.30213
S5948 Amodiaquine Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria.
Molecules, 2024, 29(6)1363
Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9
bioRxiv, 2020, 10.1101/2020.04.13.039917
S4104 Diminazene Aceturate Diminazene(Diminazene diaceturate) is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
Cell, 2024, 187(15):4095-4112.e21
Cell, 2024, 187(15):4095-4112.e21
Bone Joint Res, 2024, 13(3):110-123
S1837 Flubendazole Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.
Nat Commun, 2024, 15(1):4513
Sci Rep, 2020, 10(1):13124
RSC Advances, 2018, 10.1039/C7RA12259D
S1691 Praziquantel Praziquantel is an anthelmintic effective against flatworms.
Parasitology, 2020, 1-11
PLoS Negl Trop Dis, 2015, 9(3):e0003593
S2028 Diclazuril Diclazuril(R-64433) is an anti-coccidial drug.
Hum Mol Genet, 2020, ddaa244
S1851 Oxibendazole Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
Oncol Lett, 2018, 15(2):2218-2226
S1830 Oxfendazole Oxfendazole (RS-8858,Fenbendazole sulfoxide) is a broad spectrum benzimidazole anthelmintic.
Mol Med Rep, 2019, 19(4):2921-2926
E3814 Phyllanthus Urinaria Extract Phyllanthus Urinaria Extract is extracted from Phyllanthus urinaria (L.), which is used to treat jaundice, diabetes, malaria, and liver diseases.
Phytomedicine, 2024, 10.1016/j.phymed.2023.155091
S3741 Benznidazole Benznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.
Int J Mol Sci, 2024, 25(8)4413
Microorganisms, 2022, 10(7)1421
S4422 Nitenpyram Nitenpyram(Bestguard,Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.
Proc Natl Acad Sci U S A, 2020, 117(21):11321-11327
S5345 Nerolidol Nerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.
Int Immunopharmacol, 2020, 80:106118
S4068 Tinidazole Tinidazole (CP12574) is an anti-parasitic drug.
Int J Mol Sci, 2024, 25(8)4413
Microorganisms, 2022, 10(7)1421
S3889 Arteether Arteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite.
ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S5094 Maduramycin Ammonium Maduramicin, which could be isolated from the actinomycete Actinomadura rubra, is an antiprotozoal agent used in veterinary medicine to prevent coccidiosis.
Cancers (Basel), 2019, 11(6)
S2468 Fenbendazole Fenbendazole(Fenbendazol,Phenbendasol) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
S2501 Pyrantel Pamoate Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.
S4141 Dinitolmide Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug.
S4044 Toltrazuril Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
S4094 Tetramisole HCl Tetramisole(R-829,(±)-Tetramisole hydrochloride) is a mixture of dextro- and levo isomers used as an anthelmintic.
E3040 Stemonae Extract Stemonae Extract is extracted from Radix Stemonae, has been widely used as an oral anti-tussive agent in traditional Chinese medicine (TCM) for thousands of years with pharmacological effects as anti-tussive, anti-tuberculous, anti-bacterial, anti-fungal and anti-helminthic.
S3999 α-santonin α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent.
S4866 Nicarbazin Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug.
E3182 Carica Papaya Fruit Extract Carica Papaya Fruit Extract is extracted from the fruit of Carica Papaya, which has proven antihelminthic and anti-amoebic activities.
E3085 Dichroae Radix Extract Dichroae Radix Extract is drawed from Dichroae radix, exhibits good clinical efficacy in treatments as an antimalarial, expectorant or antifebrile agent in Chinese medicine, and it also has an anticoccidial effect in chickens infected by coccidiosis when used alone or as the main herb to formulate a complex.
S4876 Robenidine Hydrochloride Robenidine Hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) is an anticoccidial agent mainly for poultry.
E3101 Toosendan Fructus Extract Toosendan Fructus Extract is extracted from Fructus Meliae Toosendan, which has potent anticoccidial effects and also acts as an alternative anticoccidial agent for avian coccidiosis control.
E3111 Tribulus Terrestris Extract Tribulus Terrestris Extract is extracted from Tribulus Terrestris, which has anti-inflammatory, analgesic, antispasmodic, anticancer, antibacterial, anthelmintic, larvicidal, and anticariogenic activities.
S4145 Decoquinate Decoquinate is a coccidiostat.
S4599 Benzyl benzoate Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
S0081 DDD107498 DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.
S4167 Cyromazine Cyromazine(Cyromazin,CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide.
S5722 Oxantel Pamoate Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting.
S4898 Sulfalozine sodium Sulfalozine sodium (Sulfaclozine sodium, Sulfachlopryrazine sodium) is an antiprotozoal useful in coccidiosis research.
S4882 Resorantel Resorantel is a safe, hydroxybenzanilide cestocide highly effective against Moniezia and Thysaniezia spp. and moderately effective against Paramphistomum spp.
S5017 Oxyclozanide Oxyclozanide (Oxiclozanidum, Zanil, Oxyclozanid, Zanilox) is a salicylanilide anthelmintic and mitochondrial uncoupling anthelmintic drug approved for veterinary use.
S3713 Moxidectin Moxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari.
S3707 Ethopabate Ethopabate (ETP, Ethyl pabate) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens.
S5055 Milbemycin Oxime Milbemycin Oxime is a broad spectrum anti-parasitic drug that is active against worms (anthelmintic) and mites (miticide).
S5031 Sulfaquinoxaline sodium Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na) is the sodium salt of sulfaquinoxaline, which is often used as a drug to prevent coccidiosis in poultry, swine, and sheep by inhibiting the synthesis of nucleic acids and proteins in microorganisms.
E3145 Kochiae Fructus Extract Kochiae Fructus Extract is obtained from dried fruit of Kochia scoparia (L.) Schrad., broom cypress fruit), has attracted considerable attention for its pharmacological activities, including antiinflammation, antidiabetics, insecticide, antianaphylaxis, antipruritic and anti-rheumatoid arthritis.
S3591 Eprinomectin Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity.
E3165 Rabdosiae Rubescentis Herba Extract Rabdosiae Rubescentis Herba Extract is drawed from the dried aerial part of genus Rabdosia rubescens (Hemsl.) Hara of the Lamiaceae family, which possesses several biological activities, such as anti-bacteria, anti-parasites, anti-inflammation, and anticancer.
S5093 Rafoxanide Rafoxanide (Disalan, Ranide, Flukanide, Bovanide) is a salicylanilide used as an anthelmintic, being effective treatment for the control of fluke infections in animals.
S5092 Febantel Febantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) is a prodrug that is metabolized to fenbendazole and oxfendazole, which are undoubtedly the active parasiticides.
S5557 Aklomide Aklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry.
S4443 Piperazine adipate Piperazine adipate is a broad spectrum anthelmintic agent that inhibits malate oxidation in Ascaridia galli and Heterakis gallinae.
S0467 Emodepside Emodepside (QHT06, BAY 44-4400, PF 1022-221), a semisynthetic derivative of PF1022A, is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Emodepside activates Ca-dependent SLO-1-like K channels.
S4389 Bephenium Hydroxynaphthoate Bephenium(NSC 759245) is an activator of B-type Acetylcholine receptor (AChR). Bephenium selectively activates the Hco-L-AChR1 subtype made of Hco-UNC-29.1, Hco-UNC-38, Hco-UNC-63, Hco-ACR-8 subunits. Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.
S4564 Diethylcarbamazine citrate Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.
S4999 Avermectin B1 Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.
Cancer Chemother Pharmacol, 2024, 94(4):599-613
S1265 SQ109 SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for LLC-MK2 culture-derived trypomastigotes of 50±8 nM, targets MmpL3 (mycobacterial membrane protein large 3) in Mycobacterium tuberculosis.
S5247 Selamectin Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.

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