Home Microbiology Parasite inhibitor - COVID-19 inhibitor Praziquantel For research use only.

Praziquantel

Praziquantel is an anthelmintic effective against flatworms.

Praziquantel Chemical Structure

Praziquantel Chemical Structure

CAS No. 55268-74-1

Purity & Quality Control

Batch: S169101 DMSO]63 mg/mL]false]Ethanol]63 mg/mL]false]Water]Insoluble]false Purity: 99.83%
99.83

Praziquantel Related Products

Biological Activity

Description Praziquantel is an anthelmintic effective against flatworms.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05321992 Not yet recruiting
Cholangiocarcinoma|Liver Fluke-Related Cholangiocarcinoma|Opisthorchiasis
McMaster University|Khon Kaen University|Global Alliance for Chronic Diseases (GACD)|Canadian Institutes of Health Research (CIHR)
 July 1 2024 Not Applicable
NCT04635553 Unknown status
Schistosomiasis
Institut de Recherche pour le Developpement
 August 11 2020 --
NCT04314037 Completed
Healthy
Merck Healthcare KGaA Darmstadt Germany an affiliate of Merck KGaA Darmstadt Germany
 June 17 2020 Phase 1
NCT03870204 Completed
Aged ≥2 Years in Schistosomiasis Affected Areas
Ina-Respond|National Institute of Health Research and Development Ministry of Health Republic of Indonesia|The National Institute of Allergy and Infectious Diseases United States
 September 4 2019 --
NCT03437447 Completed
Healthy
Merck KGaA Darmstadt Germany
 June 18 2018 Phase 1

Chemical Information & Solubility

Molecular Weight 312.41 Formula

C19H24N2O2
CAS No. 55268-74-1 SDF Download Praziquantel SDF
Smiles C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 63 mg/mL ( (201.65 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 63 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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