Home Microbiology Parasite inhibitor Benzyl benzoate For research use only.

Benzyl benzoate

Synonyms: Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester

Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.

Benzyl benzoate Chemical Structure

Benzyl benzoate Chemical Structure

CAS No. 120-51-4

Purity & Quality Control

Benzyl benzoate Related Products

Biological Activity

Description Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
In vitro
In vitro Benzyl benzoate possess oestrogenic activity in MCF7 human breast cancer cells in vitro. It is able to increase the growth of oestrogen-dependent MCF7 human breast cancer cells[1].
Cell Research Cell lines Oestrogen-responsive MCF7 human breast cancer cell line
Concentrations 0-100 μM
Incubation Time 7 days
Method

Cells are added to the required volume of phenol red-free RPMI 1640 medium containing 5% DCFCS at a concentration of about 0.2 × 105 cells ml−1 and plated in monolayer in 0.5 ml aliquots into 24-well plastic tissue culture dishes (Nunc). After 24 h, the medium is changed to the same medium but containing the required concentration of test compound. Culture medium is changed routinely every 3–4 days. Cell counts are performed by counting released nuclei on a model ZBI Coulter Counter.

Chemical Information & Solubility

Molecular Weight 212.24 Formula

C14H12O2
CAS No. 120-51-4 SDF Download Benzyl benzoate SDF
Density 1.118 g/mL at 20 °C
Smiles C1=CC=C(C=C1)COC(=O)C2=CC=CC=C2
Storage (From the date of receipt) 2 year -80°C liquid

In vitro
Batch:


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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