Home Epigenetics HDAC inhibitor BRD-6929 For research use only.

BRD-6929

BRD-6929 is an inhibitor of histone deacetylase 1 (HDAC1) and HDAC2 with an IC50s of 0.04 µM and 0.1 µM, respectively. It exhibits antiproliferative activities against a human cancer cell line (HCT116) and in human mammary epithelial cells (HMEC).

BRD-6929 Chemical Structure

BRD-6929 Chemical Structure

CAS No. 849234-64-6

Purity & Quality Control

Batch: E039101 DMSO]17 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 98.15%
98.15

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Biological Activity

Description BRD-6929 is an inhibitor of histone deacetylase 1 (HDAC1) and HDAC2 with an IC50s of 0.04 µM and 0.1 µM, respectively. It exhibits antiproliferative activities against a human cancer cell line (HCT116) and in human mammary epithelial cells (HMEC).

Chemical Information & Solubility

Molecular Weight 351.42 Formula

C₁₉H₁₇N₃O₂S
CAS No. 849234-64-6 SDF Download BRD-6929 SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 17 mg/mL ( (48.37 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
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In vivo Formulation Calculator

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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