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HD1 Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S1484 MC1568 MC1568 is a selective HDAC inhibitor for maize HD1-A with IC50 of 100 nM in a cell-free assay. It is 34-fold more selective for HD1-A than HD1-B. Selective HD1-A (Maize), IC50: 100 nM; HD1-B (Maize), IC50: 3.4 μM
S2170 Givinostat (ITF2357) Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM in cell-free assays. Phase 2. Pan HD1-B, IC50: 7.5 nM; HD1-A, IC50: 16 nM