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Anti-TGFb1 (M7824)
Anti-TGFb1 (M7824) is a bifunctional monoclonal antibody targeting programmed death ligand 1 (PD-L1) and transforming growth factor beta 1 (TGFb1). It exhibits anti-tumor efficacy against breast and colon carcinomas.
Purity & Quality Control
Batch:
A269501
Purity:
99%
Protein concentration: 5.17mg/ml
Endotoxin Level: ＜1EU/mg
99
Choose Selective TGF-beta/Smad Inhibitors
| Name | Citation | ALK1 | ALK2 | ALK3 | ALK4 | TGFβRI/ALK5 | ALK6 | TGFβRII | TGF-β | Smad3 | Others |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SB431542 | 685 | ||||||||||
| LDN-193189 | 234 | ||||||||||
| Galunisertib (LY2157299) | 181 | ||||||||||
| LY2109761 | 127 | ||||||||||
| SB525334 | 104 | ||||||||||
| SB505124 | 34 | ||||||||||
| GW788388 | 24 | ||||||||||
| LY364947 | 49 | RIPK2,CK1δ,MLK-7K | |||||||||
| RepSox (E-616452) | 69 | ||||||||||
| LDN-193189 2HCl | 94 | ||||||||||
| K02288 | 23 | ||||||||||
| LDN-214117 | 4 | ||||||||||
| SD-208 | 20 | ||||||||||
| Vactosertib (TEW-7197) | 22 | ||||||||||
| ML347 | 5 | ||||||||||
| LDN-212854 | 7 | ||||||||||
| DMH1 | 48 | ||||||||||
| Alantolactone | STAT3 | ||||||||||
| SIS3 HCl | |||||||||||
| Hesperetin | Histamine receptor |
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.
Biological Activity
| Description | Anti-TGFb1 (M7824) is a bifunctional monoclonal antibody targeting programmed death ligand 1 (PD-L1) and transforming growth factor beta 1 (TGFb1). It exhibits anti-tumor efficacy against breast and colon carcinomas. |
|---|
Product Details
| Molecular Weight | 178 |
|---|---|
| Isotype | Human IgG1 |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100mMPro-Ac,20mMArg-Ac，pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
Comparison of Clones for
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
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