Home TGF-beta/Smad TGF-beta/Smad modulator - Histamine Receptor inhibitor Hesperetin For research use only.

Hesperetin

Hesperetin is a bioflavonoid and, to be more specific, a flavanone.

Hesperetin Chemical Structure

Hesperetin Chemical Structure

CAS No. 520-33-2

Purity & Quality Control

Hesperetin Related Products

Signaling Pathway

TGF-beta/Smad Signaling Pathways

TGF-beta/Smad Signaling Pathway

Biological Activity

Description Hesperetin is a bioflavonoid and, to be more specific, a flavanone.
Targets
Histamine receptor [1] TGF-β [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05073523 Completed
Healthy
Chalmers University of Technology
 September 27 2021 Not Applicable
NCT04731987 Active not recruiting
Metabolic Syndrome|Vascular Compliance|Predisposition to Cardiovascular Disease
University Hospital Clermont-Ferrand|UMR 1019 Unité de Nutrition Humaine INRAE Auvergne-Rhône Alpes Center|Department of Beverage Research Chair of analysis and technology of plant-based foods Geisenheim University|European Fruit Juice Association (AIJN)
 February 24 2021 Not Applicable
NCT02380144 Unknown status
Healthy
University of Hohenheim
 January 2014 Not Applicable
NCT02627547 Completed
Healthy
University of Glasgow
 September 2013 Not Applicable

Chemical Information & Solubility

Molecular Weight 302.27 Formula

C16H14O6
CAS No. 520-33-2 SDF Download Hesperetin SDF
Smiles COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 60 mg/mL ( (198.49 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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