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ALK1
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ALK4
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TGFβRII
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ALK7

ALK7 Inhibitors

Catalog No.	Product Name	Information	Selective / Pan	IC50 / Ki
S7692	A-83-01	A-83-01 is a potent inhibitor of TGF-β type I receptor (ALK5-TD) with IC50 of 12 nM. A-83-01 also inhibits the transcription induced by activin/nodal type I receptor (ALK4-TD) and nodal type I receptor (ALK7-TD) with IC50 of 45 nM and 7.5 nM, respectively.Solutions are unstable and should be fresh-prepared.	Pan	ALK7, IC50: 7.5 nM
S1067	SB431542	SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM in a cell-free assay, 100-fold more selective for ALK5 than p38 MAPK and other kinases.	Pan