Active Pharmaceutical Ingredients

Catalog No.	Product Name	Information
E2363	Etrasimod(APD334)	Etrasimod(APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor with an EC50 value of 1.88 nM in CHO cells.
E0109	Fezolinetant	Fezolinetant (ESN-364) is a potential antagonist of the neurokinin 3 receptor (NK3R). It interrupts pulsatile lh secretion and moderates levels of ovarian hormones throughout the menstrual cycle.
S6635	Seladelpar	Seladelpar(MBX-8025) is a potent and selective agonist of peroxisome proliferator–activated receptor-delta (PPAR-δ) with EC50 of 2 nM for human PPAR-δ. MBX-8025 enhances insulin sensitivity, counters dyslipidemia, and reduces hepatic storage of lipotoxic lipids, thereby ameliorating NASH pathology in obese diabetic mice.
S9633	GS-6207	GS-6207 (Lenacapavir) is a HIV-1 capsid inhibitor. It shows anti-HIV activity with an EC50 of 0.1 nM in MT-4 cells.