Home Metabolism P450 (e.g. CYP17) inhibitor Uniconazole (S 3307D) For research use only.

Uniconazole (S 3307D)

Synonyms: XE 1019D

Uniconazole (S 3307D, XE 1019D) is a well known inhibitor of cytochrome P450 monooxygenase that prevents the biosynthesis of trans-zeatin. Uniconazole targets CYP735As with Ki of 22 μM.

Uniconazole (S 3307D) Chemical Structure

Uniconazole (S 3307D) Chemical Structure

CAS No. 83657-22-1

Purity & Quality Control

Uniconazole (S 3307D) Related Products

Signaling Pathway

P450 (e.g. CYP17) Signaling Pathways

P450 (e.g. CYP17) Signaling Pathway

Biological Activity

Description Uniconazole (S 3307D, XE 1019D) is a well known inhibitor of cytochrome P450 monooxygenase that prevents the biosynthesis of trans-zeatin. Uniconazole targets CYP735As with Ki of 22 μM.
Targets
ABA 8′-hydroxylase [1]
(Cell-free assay)		 CYP735A1 [1]
(Cell-free assay)
10 nM(Ki) 22 μM(Ki)
In vitro
In vitro Uniconazole inhibits CK biosynthesis by suppressing CYP735A activity in Arabidopsis. Uniconazole inhibits the biosynthesis of gibberellin (GA), and brassinosteroid (BR) and the catabolism of abscisic acid (ABA)[1].

Chemical Information & Solubility

Molecular Weight 291.78 Formula

C15H18ClN3O
CAS No. 83657-22-1 SDF Download Uniconazole (S 3307D) SDF
Smiles CC(C)(C)C(C(=CC1=CC=C(C=C1)Cl)N2C=NC=N2)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 58 mg/mL ( (198.77 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 58 mg/mL

Water : Insoluble


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In vivo
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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