Uniconazole (S 3307D)

Catalog No.S3660 Batch:S366001

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Technical Data

Formula

C15H18ClN3O

Molecular Weight 291.78 CAS No. 83657-22-1
Solubility (25°C)* In vitro DMSO 58 mg/mL (198.77 mM)
Ethanol 58 mg/mL (198.77 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Uniconazole (S 3307D, XE 1019D) is a well known inhibitor of cytochrome P450 monooxygenase that prevents the biosynthesis of trans-zeatin. Uniconazole targets CYP735As with Ki of 22 μM.
Targets
ABA 8′-hydroxylase [1]
(Cell-free assay)
CYP735A1 [1]
(Cell-free assay)
10 nM(Ki) 22 μM(Ki)
In vitro Uniconazole inhibits CK biosynthesis by suppressing CYP735A activity in Arabidopsis. Uniconazole inhibits the biosynthesis of gibberellin (GA), and brassinosteroid (BR) and the catabolism of abscisic acid (ABA)[1].

Protocol (from reference)

Selleck's Uniconazole (S 3307D) has been cited by 2 publications

Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance [ Nat Microbiol, 2022, 10.1038/s41564-022-01072-5] PubMed: 35314781
Ultra-fast proteomics with Scanning SWATH [ Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4] PubMed: 33767396

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

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