Home PI3K/Akt/mTOR Akt modulator - mTOR modulator - p38 MAPK modulator Rotundic acid For research use only.

Rotundic acid

Synonyms: Rutundic acid

Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways.

Rotundic acid Chemical Structure

Rotundic acid Chemical Structure

CAS No. 20137-37-5

Purity & Quality Control

Batch: S951401 DMSO]98 mg/mL]false]]]false]]]false Purity: 99.91%
99.91

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Biological Activity

Description Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways.

Chemical Information & Solubility

Molecular Weight 488.70 Formula

C30H48O5
CAS No. 20137-37-5 SDF --
Smiles CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)CO)O)C)C)C2C1(C)O)C)C(=O)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 98 mg/mL ( (200.53 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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