Home Biosimilar Antibodies Immunology & Inflammation PD-1/PD-L1 null -VEGFR antibody Pm8002 (Anti-PD-L1 & VEGF) For research use only.
Not for use in humans.

Pm8002 (Anti-PD-L1 & VEGF)

Synonyms: BNT327

Pm8002 is a bispecific antibody targeting both PD-L1 and VEGF-A, with potential immune checkpoint inhibition, anti-angiogenic, and antineoplastic activities. It demonstrates promising antitumor effects in patients with previously treated platinum-resistant recurrent ovarian cancer (PROC) or cervical cancer, as well as in those with advanced solid tumors. MW : 172.48 KD.

Pm8002 (Anti-PD-L1 & VEGF)

Purity & Quality Control

Choose Selective PD-1/PD-L1 Inhibitors

Name Citation PD-1/PD-L1 interaction PD-1 PD-L1 PD-1/PD-L1 Others
GS-4224 0
INCB086550 1
BMS-1001 0
BMS-1166 5
PD-1/PD-L1 Inhibitor 3 12
BMS-1 12
BMS202 22
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Pm8002 is a bispecific antibody targeting both PD-L1 and VEGF-A, with potential immune checkpoint inhibition, anti-angiogenic, and antineoplastic activities. It demonstrates promising antitumor effects in patients with previously treated platinum-resistant recurrent ovarian cancer (PROC) or cervical cancer, as well as in those with advanced solid tumors. MW : 172.48 KD.

Product Details

CAS No. N/A
Source CHO
Storage
(From the date of receipt)		 -80℃

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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