Home Biosimilar Antibodies Protein Tyrosine Kinase VEGFR antibody Parsatuzumab (Anti-EGFL7) For research use only.
Not for use in humans.

Parsatuzumab (Anti-EGFL7)

Synonyms: Anti-EGFL7; RG 7414

Parsatuzumab (Anti-EGFL7) is a humanized monoclonal antibody targeting EGFL7. Parsatuzumab selectively blocks the interaction between EGFL7 and endothelial cells, potentially inhibiting vascular regrowth and reducing vascular endothelial growth factor (VEGF) inhibition. MW: 145.5 KD.

Parsatuzumab (Anti-EGFL7)

Purity & Quality Control

Choose Selective VEGFR Inhibitors

Name Citation VEGFR1 VEGFR2 VEGFR3 Others
Foretinib 93 Met,Tie-2,RON
Cediranib (AZD2171) 66 c-Kit,PDGFRβ,FGFR1
PD173074 120 FGFR1
Dovitinib (TKI-258) 49 FLT3,c-Kit,FGFR1
Linifanib (ABT-869) 32 CSF-1R,FLT3,Kit
Vatalanib (PTK787) 2HCl 51 PDGFRβ,c-Kit,c-Fms
RAF265 (CHIR-265) 23 B-Raf
Motesanib Diphosphate (AMG-706) 12 Kit,RET,PDGFR
Brivanib (BMS-540215) 9 FGFR1
MGCD-265 analog 12 Met,RON,Tie-2
AEE788 (NVP-AEE788) 13 EGFR,HER2/ErbB2,c-Abl
ENMD-2076 8 FLT3,RET,Aurora A
OSI-930 7 CSF-1R,LCK,C-Raf
CYC116 10 Aurora A,Aurora B,FLT3
Ki8751 20 c-Kit,PDGFRα
Telatinib 5 c-Kit,PDGFRα
KRN 633 6 PDGFRα,c-Kit,BTK
SAR131675 30
Apatinib (YN968D1) mesylate 23 RET
BMS-794833 1 Met
Brivanib Alaninate (BMS-582664) 2 FGFR1
Golvatinib (E7050) 8 c-Met
Semaxanib (SU5416) 19
ZM 323881 HCl 17
ZM 306416 13 Src,Abl
Sitravatinib (MGCD516) 3 DDR2,EPHA3,Axl
BFH772 0
BAW2881 (NVP-BAW2881) 2 C-Raf-1,B-RAFV599E,c-Abl
SU5402 17 FGFR1,PDGFRβ
Dovitinib (TKI258) Lactate monohydrate 30 FLT3,c-Kit,FGFR1
LY2874455 14 FGFR2,FGFR1,FGFR4
SKLB1002 4
AZD2932 3 PDGFRβ,Flt3,c-Kit
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Parsatuzumab (Anti-EGFL7) is a humanized monoclonal antibody targeting EGFL7. Parsatuzumab selectively blocks the interaction between EGFL7 and endothelial cells, potentially inhibiting vascular regrowth and reducing vascular endothelial growth factor (VEGF) inhibition. MW: 145.5 KD.

Product Details

CAS No. 1312797-14-0
Molecular Weight 145.5 kDa
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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