Home Biosimilar Antibodies Protein Tyrosine Kinase EGFR antibody Modotuximab (Anti-ERBB1 / EGFR / HER1) For research use only.
Not for use in humans.

Modotuximab (Anti-ERBB1 / EGFR / HER1)

Synonyms: null

Modotuximab (Anti-ERBB1 / EGFR / HER1) is a recombinant immunoglobulin G1 (IgG1) monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. MW: 146.6 KD.

Modotuximab (Anti-ERBB1 / EGFR / HER1)

Purity & Quality Control

Choose Selective EGFR Inhibitors

Name Citation EGFR/ErbB1 HER2/ErbB2 ErbB3 ErbB4 mutant EGFR Others
Saracatinib (AZD0530) 283 c-Src,LCK,c-YES
Canertinib (CI-1033) 46
AG-490 127 JAK2 (V617F)
CP-724714 108
WZ4002 34
Sapitinib (AZD8931) 46
CUDC-101 22 HDAC,HDAC1,HDAC6
AG-1478 96
PD153035 HCl 16
Pelitinib (EKB-569) 11 Src,MEK/ERK,Raf
AEE788 (NVP-AEE788) 13 c-Abl,FLT1,c-Fms
AC480 (BMS-599626) 10
AP26113-analog (ALK-IN-1) 4 ALK,IGF1R,INSR
WZ3146 2
Allitinib tosylate 16
Rociletinib (CO-1686) 36
Varlitinib 8
Icotinib (BPI-2009H) 8
TAK-285 4 MEK1,Aurora B,LCK
WHI-P154 11 VEGFR,Src,JAK3
Daphnetin 4 PKA,PKC
PD168393 5
CNX-2006 2
Tyrphostin 9 1 PDGFR
AG-18 1
4-AMino-1-phenylpyrazolo[3,4-d]pyriMidine 0
AST-1306 0
ErbB2 inhibitor 0
Tuxobertinib (BDTX-189) 2 RIPK2,BLK
Epertinib hydrochloride 0
JND3229 0 EGFR C797S
BI-4020 1
Tyrphostin AG-528 0
AG 556 0
Canertinib dihydrochloride 8
EGFR Inhibitor 2 Microtubules
SU5214 0 VEGFR2
RG 13022 0
TQB3804 0
zipalertinib (TAS6417) 3 TXK,BMX
Pyrotinib dimaleate 4
PD153035 14
AG 494 0
AG 555 0
Theliatinib (HMPL-309) 0
Avitinib (Abivertinib) 2 JAK3,BTK
Lazertinib 6 Del19,L85R
Lifirafenib (BGB-283) 6 WT A-RAF,C-RAF (Y340/341D),BRAF(V600E)
Nazartinib (EGF816) 6
Zorifertinib (AZD3759) 6
CL-387785 (EKI-785) 4
Poziotinib 33
AZ5104 4 BLK,ACK1,BRK
AV-412 free base 0
HER2-Inhibitor-1
WZ8040
Genistein topo II
BDTX-1535
Falnidamol
BLU-945
Sunvozertinib (DZD9008)
CH7233163
Licochalcone D PARP,Caspase,Met
Alflutinib (Furmonertinib) mesylate CYP3A4
(Rac)-JBJ-04-125-02
Tyrphostin AG30 (AG30)
AG-1557
AG99
MTX-211 PI3K
RG14620 ABCG2
Almonertinib (HS-10296)
Cyasterone
Norcantharidin c-Met
Naquotinib(ASP8273)
EAI045
Olmutinib (BI 1482694) BTK
Butein
Chrysophanic Acid mTOR
EGCG ((-)-Epigallocatechin Gallate) FASN,DNMT,telomerase
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Modotuximab (Anti-ERBB1 / EGFR / HER1) is a recombinant immunoglobulin G1 (IgG1) monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. MW: 146.6 KD.

Product Details

CAS No. 1310460-86-6
Molecular Weight 146.6
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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