Home Neuronal Signaling Adrenergic Receptor agonist Midodrine For research use only.

Midodrine

Midodrine belongs to the class of medications known as vasopressors. It is an adrenergic alpha-1 agonist.

Midodrine Chemical Structure

Midodrine Chemical Structure

CAS No. 42794-76-3

Purity & Quality Control

Batch: S573501 DMSO]51 mg/mL]false]]]false]]]false Purity: 98%
98

Midodrine Related Products

Signaling Pathway

Adrenergic Receptor Signaling Pathways

Adrenergic Receptor Signaling Pathway

Biological Activity

Description Midodrine belongs to the class of medications known as vasopressors. It is an adrenergic alpha-1 agonist.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06405555 Not yet recruiting
Heart Failure With Reduced Ejection Fraction|Hypotension|LV Dysfunction
Ottawa Heart Institute Research Corporation
 August 1 2024 Phase 2|Phase 3
NCT05240391 Completed
Paracentesis-Induced Circulatory Dysfunction
Asian Institute of Gastroenterology India
 February 20 2021 Phase 3
NCT04455464 Completed
Chronic Liver Disease
Institute of Liver and Biliary Sciences India
 July 11 2020 Not Applicable
NCT03911817 Completed
Septic Shock
Ain Shams University
 November 15 2017 Phase 4

Chemical Information & Solubility

Molecular Weight 254.28 Formula

C12H18N2O4
CAS No. 42794-76-3 SDF --
Smiles COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 51 mg/mL ( (200.56 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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