Home Neuronal Signaling Adrenergic Receptor antagonist Metipranolol For research use only.

Metipranolol

Synonyms: Betamann

Metipranolol (Betamann) is a potent β-adrenergic receptor antagonist, possessing the beta-blocking potencies (pA2) of 8.3, 8.4 at guinea pig atrial β1-adrenoceptor and β2-adrenoceptor of the rat uterus, respectively, also is a potent displacer of 3H-DHA binding, ligand concentration 0.7 nM, possessing a Ki value of 39 ± 24 nM.

Metipranolol Chemical Structure

Metipranolol Chemical Structure

CAS No. 22664-55-7

Purity & Quality Control

Batch: E052901 DMSO]62 mg/mL]false]Ethanol]62 mg/mL]false]Water]Insoluble]false Purity: 99.18%
99.18

Metipranolol Related Products

Signaling Pathway

Adrenergic Receptor Signaling Pathways

Adrenergic Receptor Signaling Pathway

Biological Activity

Description Metipranolol (Betamann) is a potent β-adrenergic receptor antagonist, possessing the beta-blocking potencies (pA2) of 8.3, 8.4 at guinea pig atrial β1-adrenoceptor and β2-adrenoceptor of the rat uterus, respectively, also is a potent displacer of 3H-DHA binding, ligand concentration 0.7 nM, possessing a Ki value of 39 ± 24 nM.
Targets
guinea pig atrial β1-adrenoceptor [1] β2-adrenoceptor of the rat uterus [1]

Chemical Information & Solubility

Molecular Weight 309.4 Formula

C17H27NO4
CAS No. 22664-55-7 SDF --
Smiles CC(C)NCC(O)COC1=CC(=C(OC(C)=O)C(=C1C)C)C
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 62 mg/mL ( (200.38 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 62 mg/mL

Water : Insoluble


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In vivo
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