Home GPCR & G Protein Adrenergic Receptor antagonist Labetalol HCl For research use only.

Labetalol HCl

Synonyms: AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W

Labetalol HCl(AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W) is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.

Labetalol HCl Chemical Structure

Labetalol HCl Chemical Structure

CAS No. 32780-64-6

Purity & Quality Control

Labetalol HCl Related Products

Signaling Pathway

Adrenergic Receptor Signaling Pathways

Adrenergic Receptor Signaling Pathway

Biological Activity

Description Labetalol HCl(AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W) is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.
Targets
α1-adrenergic receptor [1] β-adrenergic receptor [1]
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Chemical Information & Solubility

Molecular Weight 364.87 Formula

C19H25ClN2O3
CAS No. 32780-64-6 SDF Download Labetalol HCl SDF
Smiles CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 72 mg/mL ( (197.33 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 8 mg/mL

Ethanol : 7 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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