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Labetalol HCl
Synonyms: AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W
Labetalol HCl(AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W) is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.
Labetalol HCl Chemical Structure
CAS No. 32780-64-6
Purity & Quality Control
Batch:
Purity:
99.99%
99.99
Labetalol HCl Related Products
| Related Targets | α-adrenergic receptor β-adrenergic receptor Beta-Adrenergic Receptor | Click to Expand |
|---|---|---|
| Related Products | Zenidolol (ICI-118551) Hydrochloride Yohimbine HCl L755507 Atipamezole Higenamine hydrochloride Fenoterol hydrobromide Medetomidine HCl Rauwolscine hydrochloride Deoxycorticosterone acetate Detomidine HCl Naftopidil | Click to Expand |
| Related Compound Libraries | FDA-approved Drug Library Natural Product Library Bioactive Compound Library-I GPCR Compound Library | Click to Expand |
Signaling Pathway
Biological Activity
| Description | Labetalol HCl(AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W) is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure. | ||
|---|---|---|---|
| Targets |
|
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT06385600 | Not yet recruiting | Severe Pre-eclampsia |
Assiut University |
May 20 2024 | Not Applicable |
| NCT06346561 | Recruiting | Nasolacrimal Duct Obstruction |
Sohag University |
March 30 2024 | Not Applicable |
| NCT05096728 | Completed | Preeclampsia With Severe Features |
Ohio State University |
December 1 2021 | -- |
| NCT03086265 | Completed | Otorhinolaryngologic Surgical Procedures|Laser Therapy |
Stanford University |
March 24 2017 | Not Applicable |
Chemical Information & Solubility
| Molecular Weight | 364.87 | Formula | C19H25ClN2O3 |
| CAS No. | 32780-64-6 | SDF | Download Labetalol HCl SDF |
| Smiles | CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl | ||
| Storage (From the date of receipt) | |||
|
In vitro |
DMSO : 72 mg/mL ( (197.33 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.) Water : 8 mg/mL Ethanol : 7 mg/mL |
Molecular Weight Calculator |
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In vivo Add solvents to the product individually and in order. |
In vivo Formulation Calculator |
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Preparing Stock Solutions
Molarity Calculator
In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
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%
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Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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