Home Biosimilar Antibodies Immunology & Inflammation PD-1/PD-L1 inhibitor -VEGFR antibody Ivonescimab (Anti-PD-1 & VEGF) For research use only.
Not for use in humans.

Ivonescimab (Anti-PD-1 & VEGF)

Synonyms: AK 112, SMT 112

Ivonescimab is a first-in-class humanized tetravalent bispecific antibody targeting PD-1 and VEGF-A, with immune checkpoint inhibitory, anti-angiogenic, and antineoplastic activities. It is being developed for the treatment of non-small cell lung cancer (NSCLC) and other solid tumors, including breast, liver, and gastric cancers. M.W 201.12 kDa

Ivonescimab (Anti-PD-1 & VEGF)

Purity & Quality Control

Choose Selective PD-1/PD-L1 Inhibitors

Name Citation PD-1/PD-L1 interaction PD-1 PD-L1 PD-1/PD-L1 Others
GS-4224 0
INCB086550 1
BMS-1001 0
BMS-1166 5
PD-1/PD-L1 Inhibitor 3 12
BMS-1 12
BMS202 22
CA-170 (AUPM-170)
SR 0987 IL17,RORγt
Spartalizumab (anti-PD-1)
Camrelizumab (anti-PD-1)
AUNP-12
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Ivonescimab is a first-in-class humanized tetravalent bispecific antibody targeting PD-1 and VEGF-A, with immune checkpoint inhibitory, anti-angiogenic, and antineoplastic activities. It is being developed for the treatment of non-small cell lung cancer (NSCLC) and other solid tumors, including breast, liver, and gastric cancers. M.W 201.12 kDa

Product Details

CAS No. 2428381-53-5
Source CHO
Storage
(From the date of receipt)		 -80℃

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Ivonescimab (Anti-PD-1 & VEGF) | Ivonescimab (Anti-PD-1 & VEGF) supplier | purchase Ivonescimab (Anti-PD-1 & VEGF) | Ivonescimab (Anti-PD-1 & VEGF) cost | Ivonescimab (Anti-PD-1 & VEGF) manufacturer | order Ivonescimab (Anti-PD-1 & VEGF) | Ivonescimab (Anti-PD-1 & VEGF) distributor