Home PI3K/Akt/mTOR PI3K inhibitor - Dyes chemical Gallein For research use only.

Gallein

Synonyms: Pyrogallol phthalein

Gallein (Pyrogallol phthalein) is an inhibitor of G protein βγ (G beta-gamma complex, Gβγ) subunit interaction with PI3 kinase. Gallein inhibits β-ionone effects and exhibits anti-tumor activity. Gallein can be used as a biological stain.

Gallein Chemical Structure

Gallein Chemical Structure

CAS No. 2103-64-2

Purity & Quality Control

Batch: S597801 DMSO]73 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.80%
99.80

Gallein Related Products

Signaling Pathway

PI3K Signaling Pathways

PI3K Signaling Pathway

Biological Activity

Description Gallein (Pyrogallol phthalein) is an inhibitor of G protein βγ (G beta-gamma complex, Gβγ) subunit interaction with PI3 kinase. Gallein inhibits β-ionone effects and exhibits anti-tumor activity. Gallein can be used as a biological stain.
Targets
Gβγ [1] PI3 kinase [1]
In Vivo
In vivo

Gallein pre-treatment does not abolish BNP/NMB-mediated elevation of intracellular ca2+ concentration but leads to a ~50% reduction in intracellular ca2+ concentration. [3]
Animal Research Animal Models C57BI/6 mice
Dosages 10 µL for i.t. & 50 µL for i.d
Administration i.d.&i.t.

(Data sourced from selleck products)

Chemical Information & Solubility

Molecular Weight 364.31 Formula

C20H12O7
CAS No. 2103-64-2 SDF --
Smiles OC1=C(O)C2=C(C=C1)C3(OC(=O)C4=CC=CC=C34)C5=C(O2)C(=C(O)C=C5)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 73 mg/mL ( (200.37 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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