Gallein

Catalog No.S5978 Batch:S597801

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Technical Data

Formula

C20H12O7

Molecular Weight 364.31 CAS No. 2103-64-2
Solubility (25°C)* In vitro DMSO 73 mg/mL (200.37 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Gallein (Pyrogallol phthalein) is an inhibitor of G protein βγ (G beta-gamma complex, Gβγ) subunit interaction with PI3 kinase. Gallein inhibits β-ionone effects and exhibits anti-tumor activity. Gallein can be used as a biological stain.
Targets
Gβγ [1] PI3 kinase [1]
In vivo

Gallein pre-treatment does not abolish BNP/NMB-mediated elevation of intracellular ca2+ concentration but leads to a ~50% reduction in intracellular ca2+ concentration. [3]

Protocol (from reference)

Animal Study:

[3]

  • Animal Models

    C57BI/6 mice

  • Dosages

    10 µL for i.t. & 50 µL for i.d

  • Administration

    i.d.&i.t.

    (Data sourced from selleck products)

Selleck's Gallein has been cited by 1 publication

BNP facilitates NMB-encoded histaminergic itch via NPRC-NMBR crosstalk [ Elife, 2021, 10e71689] PubMed: 34919054

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.