K562 |
Function Assay |
10mM |
1h |
|
decreases the expression of LC3-II and the formation of autophagosomes |
21864037 |
Jurkat |
Function Assay |
10mM |
1h |
|
decreases the expression of LC3-II and the formation of autophagosomes |
21864037 |
HeLa |
Cytotoxicity Assay |
2mM |
24h |
|
inhibites the cytotoxicity of silibinin to HeLa cells. |
21875385 |
PC12/TetOn |
Function Assay |
0.1/1mM |
18h |
|
leads to α-syn(WT) accumulation, toxicity, and oligomer formation |
21906659 |
RMPI8226 |
Function Assay |
5mM |
1h |
|
suppresses the level of autophagy under nutrient depletion |
21915620 |
MCF-7 |
Function Assay |
10mM |
48h |
|
blocks autophagy induced by bortezomib |
21931937 |
HBx |
Apoptosis Assay |
10mM |
48h |
DMSO |
increases cell death |
22020078 |
Marc-145 |
Function Assay |
5mM |
12/24/36h |
|
reduces the PRRSV titers and the protein expression |
22119900 |
U937 |
Function Assay |
2mM |
12h |
|
decreases the autophagy ratio |
22155150 |
BGC-823 |
Function Assay |
5mM |
2h |
|
inhibits the rate of autophagic cells |
22322152 |
A549 |
Function Assay |
0.1mM |
24h |
|
suppresses SU11274-induced cell death |
22466960 |
pDCs |
Function Assay |
10mM |
0.5h |
|
reduces the induction of IFN-α by ssRNA40 |
22396599 |
HeLa |
Apoptosis Assay |
5mM |
24h |
|
induces caspase-dependent cell death |
22545128 |
U251 |
Apoptosis Assay |
5mM |
24h |
|
increases S1-induced cell death |
22579788 |
MCF-7 |
Apoptosis Assay |
0.1mM |
6h |
|
enhances sirtinol-induced apoptosis |
22751989 |
PC-3 |
Apoptosis Assay |
2mM |
2h |
|
increases ORI-induced cell death |
22745580 |
HCT116 |
Apoptosis Assay |
5mM |
24h |
DMSO |
enhances apigenin-induced cell death |
24626522 |
U2OS |
Growth Inhibition Assay |
10mM |
24h |
|
intensifies the growth inhibition induced by Dox |
24639013 |
A2780cp |
Apoptosis Assay |
2.5mM |
1h |
ddH2O |
enhances cisplatin-induced cell death |
24817946 |
HepG2 |
Function Assay |
5mM |
4h |
|
increases cellular levels of HL |
24713587 |
Microglia |
Apoptosis Assay |
5mM |
24h |
|
decreases hypoxia-induced cell death |
24818601 |
MDA-MB 231 |
Apoptosis Assay |
5mM |
0.5h |
|
modulates Tocomin® induced apoptosis |
24830781 |
PANC-1 |
Apoptosis Assay |
1mM |
48h |
DMSO |
enhances bortezomib-induced cell viability loss |
24842158 |
MDA-MB-231 |
Function Assay |
2mM |
48h |
|
promotes TM-induced cell death |
24970676 |
MDA-MB-231 |
Function Assay |
2mM |
24h |
|
inhibits autophagy induced by TM |
24970676 |
MCF-7 |
Function Assay |
2mM |
48h |
|
promotes TM-induced cell death |
24970676 |
MCF-7 |
Function Assay |
2mM |
24h |
|
inhibits autophagy induced by TM |
24970676 |
HepG2 |
Apoptosis Assay |
3mM |
5h |
|
reduces cell apoptosis induced by QDs |
22836595 |
HeLa |
Apoptosis Assay |
10mM |
2h |
|
decreases cell viability co-treatment with PEI |
23000135 |
SK-HEP-1 |
Apoptosis Assay |
10mM |
1h |
|
protects against autophagy and induces apoptosis in bufalin-treated cells |
22858649 |
MDA-MB231 |
Function Assay |
5mM |
1h |
|
increases resveratrol-mediated caspase activation and cell death |
23088850 |
PaCa44 |
Apoptosis Assay |
2.5mM |
1h |
|
reduces genipin-mediated apoptosis |
23124112 |
T-47D |
Function Assay |
10mM |
2h |
|
inhibits autophagy process and increases rapamycin induced apoptosis |
23300026 |
GTL-16 |
Apoptosis Assay |
5mM |
24h |
|
reduces cell viability as compared to cells treated with MET inhibitors |
23313490 |
U251MG |
Function Assay |
3mM |
1h |
|
suppresses LC3-II protein expression |
23338618 |
T24 |
Function Assay |
10mM |
1h |
|
reduces the cleavage of LC3 after baicalin treatment |
23354080 |
HUVECs |
Function Assay |
3mM |
24h |
|
blocks the protective effect of resveratrol by inhibiting autophagy |
23358928 |
MCF-7 |
Function Assay |
5mM |
24h |
|
inhibits starvation-induced autophagy |
23395679 |
Hela |
Function Assay |
5mM |
24h |
|
inhibits starvation-induced autophagy |
23395679 |
OR6 |
Function Assay |
10mM |
72h |
|
suppresses HCV replication and formation of autophagosomes |
23395875 |
HT-29 |
Function Assay |
1mM |
48/96h |
|
inhibits AMPK induces autophagic cell death |
23508272 |
SH-SY5Y |
Cytotoxicity Assay |
5mM |
24h |
|
increases PCN toxicity |
23525265 |
Saos-2 |
Apoptosis Assay |
1mM |
96h |
|
increases cell death induced by PCX |
23563171 |
1321N1 |
Cytotoxicity Assay |
5mM |
24h |
|
protects cell against PCN-induced toxicity |
23525265 |
A2780 |
Apoptosis Assay |
5mM |
24h |
|
converts FTY720 with CDDP into an additive effect towards killing ovarian cancer cells |
23592281 |
OV2008 |
Apoptosis Assay |
5mM |
24h |
|
converts FTY720 with CDDP into an additive effect towards killing ovarian cancer cells |
23592281 |
PC12 |
Function Assay |
10mM |
24h |
water |
inhibits chymotrypsin-like proteasomal activity. |
23603979 |
SH-SY5Y |
Apoptosis Assay |
5mM |
1h |
|
abolishes celastrol neuroprotective effect |
23619395 |
SH-SY5Y |
Function Assay |
1mM |
24h |
|
inhibits the autophagy induced by TOCP |
23743148 |
HepG2 |
Function Assay |
10mM |
24h |
|
inhibits siTIGAR- and HBSS-induced autophagy |
23817040 |
HeLa |
Function Assay |
10mM |
2h |
|
suppresses LC3 II expressison |
23864738 |
HONE-1 |
Function Assay |
5mM |
1h |
|
represses 6r-mediated ROS production |
23892358 |
MCF7 |
Function Assay |
5mM |
24h |
|
increases CuO induced cell death |
23962629 |
HO8910 |
Apoptosis Assay |
10mM |
12h |
|
enhances B19-induced apoptosi |
23983610 |
SMMC-7721 |
Apoptosis Assay |
5mM |
24h |
|
attenuates TNF-α protection against serum starvation-mediated apoptosis |
24066693 |
Hep3B |
Apoptosis Assay |
5mM |
24h |
|
attenuates TNF-α protection against serum starvation-mediated apoptosis |
24066693 |
H460 |
Function Assay |
10mM |
4h |
|
increases cisplatin-induced cell death |
24173208 |
A549 |
Function Assay |
10mM |
4h |
|
inhibits autophagy induced by irradiation |
24142735 |
H1299 |
Function Assay |
10mM |
4h |
|
increases cisplatin-induced cell death |
24173208 |
WiDr |
Function Assay |
10mM |
1h |
|
inhibits PCBL-induced LC3 II expression |
24190489 |
LoVo |
Apoptosis Assay |
5mM |
48h |
|
enhances DCA-induced apoptosis. |
24201812 |
HepG2 E47 |
Function Assay |
2.5mM |
48h |
|
increases the toxicity of AA, BSO, and CCl4 |
24273738 |
RKO |
Function Assay |
2mM |
1h |
DMSO |
enhances cell death by geldanamycin |
24291777 |
Hep3B |
Apoptosis Assay |
2mM |
12h |
DMSO |
inhibits AZD8055-induced cell death |
24297300 |
ACHN-5968 |
Apoptosis Assay |
5mM |
3h |
|
enhances paclitaxel-mediated apoptosis |
24305604 |
Huh7 |
Apoptosis Assay |
2mM |
12h |
DMSO |
inhibits AZD8055-induced cell death |
24297300 |
UOK257 |
Apoptosis Assay |
5mM |
3h |
|
enhances paclitaxel-mediated apoptosis |
24305604 |
ECSCs |
Apoptosis Assay |
10mM |
4h |
|
decreases rapamycin-treated apoptosis |
24319109 |
MCF-7 |
Function Assay |
10mM |
24h |
|
inhibits the autophagy induced by chemotherapy drugs |
24315578 |
SGC-7901 |
Apoptosis Assay |
2mM |
1h |
|
increases CA-4 induced apoptosis |
24321340 |
SMMC-7721 |
Apoptosis Assay |
2mM |
1h |
|
increases CA-4 induced apoptosis |
24321340 |
T24 |
Apoptosis Assay |
5mM |
1.5h |
|
potentiates celecoxib-induced apoptosis |
24349176 |
NTUB1 |
Apoptosis Assay |
5mM |
1.5h |
|
potentiates celecoxib-induced apoptosis |
24349176 |
MG-63 |
Apoptosis Assay |
10mM |
12h |
|
enhances DP-induced apoptosis |
24358301 |
MG-63 |
Apoptosis Assay |
0.5/1mM |
32h |
|
enhances salinomycin-induced cell apoptosis |
24358342 |
MG-63 |
Function Assay |
0.5/1mM |
48h |
|
induces salinomycin-induced cell viability loss |
24358342 |
U2OS |
Function Assay |
0.5/1mM |
48h |
|
induces salinomycin-induced cell viability loss |
24358342 |
HGC-27 |
Function Assay |
10mM |
1h |
|
inhibits the cell viability loss by RAD001 or MK-2206 |
24416349 |
HCT116 |
Apoptosis Assay |
5mM |
24h |
|
enhances the apoptosis induced by apigenin |
24626522 |
A549 |
Apoptosis Assay |
10mM |
48h |
|
accelerates the reduction of cell viability induced by PTX |
24626722 |
Saos-2 |
Apoptosis Assay |
10mM |
24h |
|
intensifies the growth inhibition of the U2OS cells induced by Dox |
24639013 |
U2OS |
Apoptosis Assay |
10mM |
24h |
|
intensifies the growth inhibition of the U2OS cells induced by Dox |
24639013 |
HepG2 |
Function Assay |
5mM |
4h |
|
increases HL release |
24713587 |
A549 |
Apoptosis Assay |
5mM |
48h |
|
decreases the percentage of cell death and expression levels of caspase-3, Beclin-1 and LC3-II |
24706303 |
A2780cp |
Apoptosis Assay |
2.5mM |
1h |
ddH2O |
enhances cisplatin-induced cell death |
24817946 |
Microglia |
Apoptosis Assay |
5mM |
24h |
|
decreases hypoxia-induced cell death |
24818601 |
HT-29 |
Apoptosis Assay |
1mM |
48h |
DMSO |
enhances bortezomib-induced cell viability loss |
24842158 |
MDR |
Apoptosis Assay |
10mM |
6h |
|
strengthens the power of anticancer drugs |
25019701 |
H157 |
Function Assay |
5mM |
2h |
|
suppresses SPC induced accumulation of LC3-II |
25285628 |
A549 |
Function Assay |
5mM |
2h |
|
suppresses SPC induced accumulation of LC3-II |
25285628 |
A2780cp |
Growth Inhibition Assay |
1mM |
1h |
|
increases cisplatin-induced cell death |
25322694 |
NBL-W-S |
Apoptosis Assay |
1mM |
6h |
|
increases cell apoptosis induced by GANT-61 |
25323222 |
NBL-W-S |
Growth Inhibition Assay |
1mM |
6h |
|
enhances GANT-61 toxicity |
25323222 |
A549 |
Apoptosis Assay |
5mM |
2h |
DMSO |
inhibits BDMC-induced apoptotic cell death |
25716561 |
95D |
Apoptosis Assay |
5mM |
2h |
DMSO |
inhibits BDMC-induced apoptotic cell death |
25716561 |
A549 |
Growth Inhibition Assay |
3mM |
2h |
DMSO |
reduces growth inhibitory effect of BDMC |
25716561 |
95D |
Growth Inhibition Assay |
3mM |
2h |
DMSO |
reduces growth inhibitory effect of BDMC |
25716561 |
Nara-H |
Growth Inhibition Assay |
5mM |
48h |
|
enhances temsirolimusmediated suppression of Nara-H cell proliferation |
21805033 |
HUVECs |
Function Assay |
10mM |
0.5h |
|
decreases the AGE-BSAinduced autophagy leve |
21468592 |
HepG2 |
Apoptosis Assay |
2mM |
1h |
|
enhances radiation-induced cell death |
21453691 |
U-2 OS |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells |
29435139 |
A673 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells |
29435139 |
DAOY |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells |
29435139 |
Saos-2 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells |
29435139 |
BT-37 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells |
29435139 |
RD |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells |
29435139 |
SK-N-SH |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells |
29435139 |
BT-12 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells |
29435139 |
MG 63 (6-TG R) |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells |
29435139 |
NB1643 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells |
29435139 |
OHS-50 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells |
29435139 |
Rh41 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells |
29435139 |
Rh30 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells |
29435139 |
SJ-GBM2 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells |
29435139 |
SK-N-MC |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells |
29435139 |
NB-EBc1 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells |
29435139 |
LAN-5 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells |
29435139 |
Rh18 |
qHTS assay |
|
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells |
29435139 |