Home Neuronal Signaling Adrenergic Receptor agonist Dexmedetomidine HCl For research use only.

Dexmedetomidine HCl

Synonyms: (+)-Medetomidine Hydrochloride

Dexmedetomidine HCl((+)-Medetomidine Hydrochloride) is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.

Dexmedetomidine HCl Chemical Structure

Dexmedetomidine HCl Chemical Structure

CAS No. 145108-58-3

Purity & Quality Control

Batch: S209001 DMSO]48 mg/mL]false]Ethanol]48 mg/mL]false]Water]20 mg/mL]false Purity: 99.98%
99.98

Dexmedetomidine HCl Related Products

Signaling Pathway

Adrenergic Receptor Signaling Pathways

Adrenergic Receptor Signaling Pathway

Biological Activity

Description Dexmedetomidine HCl((+)-Medetomidine Hydrochloride) is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.
Targets
alpha-2 adrenoceptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05342376 Unknown status
Postoperative Shivering|Cesarean Delivery
Rehman Medical Institute - RMI
 February 1 2022 Phase 4

Chemical Information & Solubility

Molecular Weight 236.74 Formula

C13H16N2.HCl
CAS No. 145108-58-3 SDF Download Dexmedetomidine HCl SDF
Smiles CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 48 mg/mL ( (202.75 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 48 mg/mL

Water : 20 mg/mL


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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