Chondroitin sulfate

Chondroitin sulfate (CS) is a major component of the extracellular matrix (ECM) of many connective tissues, including cartilage, bone, skin, ligaments and tendons. It reduces the IL-1β-induced nuclear factor-kB (NF-κB) translocation in chondrocytes in vitro.

Chondroitin sulfate Chemical Structure

Chondroitin sulfate Chemical Structure

CAS No. 9007-28-7

Purity & Quality Control

Batch: S241601 Water]97 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 99%
99

Chondroitin sulfate Related Products

Signaling Pathway

Biological Activity

Description Chondroitin sulfate (CS) is a major component of the extracellular matrix (ECM) of many connective tissues, including cartilage, bone, skin, ligaments and tendons. It reduces the IL-1β-induced nuclear factor-kB (NF-κB) translocation in chondrocytes in vitro.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04507074 Active not recruiting
Low Back Pain|Obesity
Poznan University of Physical Education
September 1 2020 Not Applicable
NCT03463499 Completed
Interstitial Cystitis
Samsung Medical Center
September 22 2017 Not Applicable
NCT03827161 Completed
Healthy Subject|Overweight
Fred Hutchinson Cancer Center
August 1 2017 Phase 1
NCT01856218 Completed
Mucopolysaccharidosis Type 7
Ultragenyx Pharmaceutical Inc
November 2013 Phase 1|Phase 2

Chemical Information & Solubility

Molecular Weight Formula

(C14H21NO14S)n

CAS No. 9007-28-7 SDF Download Chondroitin sulfate SDF
Smiles CC(=O)NC1C(C(C(OC1O)OS(=O)(=O)O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O
Storage (From the date of receipt)

In vitro
Batch:

Water : 97 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Chondroitin sulfate | Chondroitin sulfate supplier | purchase Chondroitin sulfate | Chondroitin sulfate cost | Chondroitin sulfate manufacturer | order Chondroitin sulfate | Chondroitin sulfate distributor