Home GPCR & G Protein Adrenergic Receptor antagonist Atipamezole hydrochloride For research use only.

Atipamezole hydrochloride

Synonyms: Antisedan, MPV-1248 hydrochloride, MPV1248 hydrochloride, MPV 1248 hydrochloride

Atipamezole (Antisedan, MPV1248) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochloride form of atipamezole.

Atipamezole hydrochloride Chemical Structure

Atipamezole hydrochloride Chemical Structure

CAS No. 104075-48-1

Purity & Quality Control

Atipamezole hydrochloride Related Products

Signaling Pathway

Adrenergic Receptor Signaling Pathways

Adrenergic Receptor Signaling Pathway

Biological Activity

Description Atipamezole (Antisedan, MPV1248) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochloride form of atipamezole.
Targets
α2 adrenergic receptor [1]

Chemical Information & Solubility

Molecular Weight 248.75 Formula

C14H16N2.HCl
CAS No. 104075-48-1 SDF Download Atipamezole hydrochloride SDF
Smiles CCC1(CC2=CC=CC=C2C1)C3=CN=CN3.Cl
Storage (From the date of receipt)

In vitro
Batch:

Ethanol : 49 mg/mL

Water : 21 mg/mL

DMSO : 12 mg/mL ( (48.24 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

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