Alacizumab (Anti-VEGFR2 / KDR / CD309)

Synonyms: CDP791

Alacizumab (Anti-VEGFR2 / KDR / CD309) is a humanized monoclonal antibody targeting VEGFR2 / KDR / CD309 . It has anti-tumour effect in tumour growth. MW :144.08 KD.

Alacizumab (Anti-VEGFR2 / KDR / CD309)

Purity & Quality Control

Choose Selective VEGFR Inhibitors

Name Citation VEGFR1 VEGFR2 VEGFR3 VEGFR VEGF Others
Foretinib 93 Met,Tie-2,RON
Cediranib (AZD2171) 67 c-Kit,PDGFRβ,FGFR1
PD173074 120 FGFR1
Dovitinib (TKI-258) 50 FLT3,c-Kit,FGFR1
Linifanib (ABT-869) 32 CSF-1R,FLT3,Kit
Vatalanib (PTK787) 2HCl 52 PDGFRβ,c-Kit,c-Fms
RAF265 (CHIR-265) 23 B-Raf
Motesanib Diphosphate (AMG-706) 12 Kit,RET,PDGFR
Brivanib (BMS-540215) 9 FGFR1
MGCD-265 analog 12 Met,RON,Tie-2
AEE788 (NVP-AEE788) 13 EGFR,HER2/ErbB2,c-Abl
ENMD-2076 8 FLT3,RET,Aurora A
OSI-930 7 CSF-1R,LCK,C-Raf
CYC116 10 Aurora A,Aurora B,FLT3
Ki8751 20 c-Kit,PDGFRα
Telatinib 5 c-Kit,PDGFRα
PP121 5 PDGFR,Hck,mTOR
KRN 633 6 PDGFRα,c-Kit,BTK
SAR131675 30
Apatinib (YN968D1) mesylate 23 RET
BMS-794833 1 Met
Brivanib Alaninate (BMS-582664) 2 FGFR1
Golvatinib (E7050) 8 c-Met
Semaxanib (SU5416) 19
ZM 323881 HCl 18
ZM 306416 13 Src,Abl
R1530 0 FGFR1
Chiauranib 0 c-Kit,CSF-1R,Aurora B
Emvododstat (PTC299) 0 Dihydroorotate dehydrogenase
XL092 0 AXL,MER,MET
Lucitanib (E3810) hydrochloride 1 FGFR1,FGFR2
Ningetinib 0 Axl,c-Met
Ki20227 1 c-Fms,PDGFRβ,c-Kit
Tyrphostin AG1433 0 PDGFRβ
SU14813 2 PDGFRβ,KIT
Sulfatinib 1 CSF1R,FGFR1
CS-2660 (JNJ-38158471) 0 RET,Kit
SU5204 1 HER2
SU5214 0 EGFR
SU5205 0
SU5408 2
Pamufetinib (TAS-115) 0 recombinant MET
ODM-203 0 FGFR3,FGFR1,FGFR2
WHI-P180 0 RET
Altiratinib 2 MET Y1230C,TrkA,TrkC
Motesanib (AMG-706) 11 c-Kit,c-Ret,PDGFR
Fruquintinib 4
Apatinib 26 RET
Cediranib Maleate 14 c-Kit,PDGFRβ,FGFR1
Toceranib phosphate 1 PDGFR
Anlotinib (AL3818) dihydrochloride 36 c-Kit
Sitravatinib (MGCD516) 4 DDR2,EPHA3,Axl
BFH772 0
BAW2881 (NVP-BAW2881) 2 C-Raf-1,B-RAFV599E,c-Abl
SU5402 17 FGFR1,PDGFRβ
Dovitinib (TKI258) Lactate monohydrate 31 FLT3,c-Kit,FGFR1
LY2874455 14 FGFR2,FGFR1,FGFR4
SKLB1002 4
AZD2932 3 PDGFRβ,Flt3,c-Kit
WAY-340935
hVEGF-IN-1
4SC-203
Chebulinic acid
Nastorazepide
Vorolanib PDGFR
MAZ51 RhoA,GSK3β,Akt
SU5208
SU5614 FLT3,c-Kit,RET
AG-13958
SKLB 610 FGFR2,PDGFR
SU1498
ZD-4190 Flt-1
PDGFR inhibitor 1 PDGFR,Kit,c-Fms
Taxifolin (Dihydroquercetin)
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Alacizumab (Anti-VEGFR2 / KDR / CD309) is a humanized monoclonal antibody targeting VEGFR2 / KDR / CD309 . It has anti-tumour effect in tumour growth. MW :144.08 KD.

Product Details

CAS No. 934216-54-3
Isotype Human IgG1
Source CHO
Formulation 100mMPro-Ac,20mMArg-Ac,pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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