Home Epigenetics Epigenetic Reader Domain inhibitor UNC-926 For research use only.

UNC-926

UNC-926 is a L3MBTL1 domain inhibitor with Kd value of 3.9 μM for binding with the MBT domain of the L3MBTL1 protein.

UNC-926 Chemical Structure

UNC-926 Chemical Structure

CAS No. 1184136-10-4

Purity & Quality Control

Batch: S526201 DMSO]67 mg/mL]false]Ethanol]2 mg/mL]false]Water]Insoluble]false Purity: 99.06%
99.06

UNC-926 Related Products

Signaling Pathway

Epigenetic Reader Domain Signaling Pathways

Epigenetic Reader Domain Signaling Pathway

Biological Activity

Description UNC-926 is a L3MBTL1 domain inhibitor with Kd value of 3.9 μM for binding with the MBT domain of the L3MBTL1 protein.
Targets
L3MBTL1 [1]
3.9 μM(Kd)

Chemical Information & Solubility

Molecular Weight 337.25 Formula

C16H21BrN2O
CAS No. 1184136-10-4 SDF --
Smiles C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=CC=C3)Br
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 67 mg/mL ( (198.66 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 2 mg/mL

Water : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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