Tedizolid

Synonyms: TR-700

Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.

Tedizolid Chemical Structure

Tedizolid Chemical Structure

CAS No. 856866-72-3

Purity & Quality Control

Batch: S527801 DMSO]10 mg/mL]false]]]false]]]false Purity: 99.69%
99.69

Tedizolid Related Products

Biological Activity

Description Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03746327 Unknown status
Prostheses Infection
Fundacion Clinic per a la Recerca Biomédica
March 1 2020 Phase 4
NCT03009045 Completed
Bone and Joint Infection
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
February 6 2017 Phase 2

Chemical Information & Solubility

Molecular Weight 370.34 Formula

C17H15FN6O3

CAS No. 856866-72-3 SDF --
Smiles CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4CC(OC4=O)CO)F
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 10 mg/mL ( (27.0 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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