Bacterial

Isoform-selective Products

Bacterial Products

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  • Bacterial Inhibitors (112)
  • New Bacterial Products
Catalog No. Product Name Information Product Use Citations Product Validations
S5159 Doxycycline Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.
Nat Genet, 2024, 56(1):124-135
Brain Behav Immun, 2024, 119:621-636
Cell Death Differ, 2024,
S1373 Daptomycin Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
Molecules, 2023, 28(2)621
Infect Drug Resist, 2023, 16:4867-4879
Infect Drug Resist, 2023, 16:4867-4879
S1835 Azithromycin Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.
Nat Commun, 2024, 15(1):6579
Int Immunopharmacol, 2024, 137:112426
mSphere, 2024, e0067124.
S2335 Oridonin Oridonin, a diterpenoid purified from Rabdosia rubescens, is a traditional agent with antitumor, anti-bacterial and anti-inflammatory effects. Oridonin inhibits AKT1 and AKT2 kinase activity with IC50 of 8.4 μM and 8.9 μM, respectively.
Inflammopharmacology, 2023, 31(4):1993-2005
J Immunol Res, 2023, 2023:5293677
J Immunother Cancer, 2022, 10(9)e005116
S1403 Tigecycline Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline induces autophagy by downregulating the PI3K-AKT-mTOR pathway.
Int J Mol Sci, 2024, 25(9)4887
Int J Mol Sci, 2024, 25(9)4887
Antimicrob Agents Chemother, 2024, 68(3):e0112023
S9046 Berberine Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.
Chin Med, 2024, 19(1):128.
Phytomedicine, 2023, 117:154918
Pharmacol Res, 2022, 185:106489
S2908 Hygromycin B Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.
Redox Biol, 2024, 76:103349
Front Pharmacol, 2024, 15:1432851
Cell Death Dis, 2023, 14(6):348
S3021 Rimonabant (SR141716) Rimonabant (SR141716) is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.
Toxicol Lett, 2023, 374:48-56
Int J Biol Sci, 2022, 18(4):1401-1414
Mol Metab, 2022, 65:101597
S1741 Rifabutin (LM427) Rifabutin (LM427, Ansamycin) is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.
Int J Mol Sci, 2022, 23(13)7383
Int J Mol Sci, 2022, 23(22)13809
ACS Infect Dis, 2022, 8(10):2171-2186
S2420 Aloperine Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
Cancer Cell Int, 2021, 21(1):662
Tissue Cell, 2021, 74:101706
J Cancer Res Clin Oncol, 2020, 10.1007/s00432-020-03157-2
S7894 Tunicamycin Tunicamycin, an antibiotic, can potently inhibit the N-linked glycosylation (NLG) by competitively inhibiting UDP-GlcNAc-dolichol-phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) activity and can target several types of tumors by reducing angiogenesis, inhibiting colony formation, and enhancing TRAIL-induced apoptosis.
Cell Discov, 2023, 9(1):92
Cell Discov, 2023, 9(1):92
Adv Sci (Weinh), 2023, 10(25):e2300414
S1097 BTZ043 Racemate BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.
Drug Deliv Transl Res, 2021, 11(4):1766-1778
J Med Chem, 2020, 28;63(10):5367-5386
Blood Adv, 2019, 3(5):797-812
S3015 Amoxicillin Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.
Ther Drug Monit, 2023, 10.1097/FTD.0000000000001100
J Pharm Biomed Anal, 2022, 219:114904
ChemMedChem, 2022, e202200043
S5535 Moxifloxacin Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.
Microorganisms, 2022, 10(7)1421
Transl Vis Sci Technol, 2018, 7(2):11
J Pharmacol Toxicol Methods, 2017, 90:39-47
S5784 Vancomycin Vancomycin is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria.
Infect Drug Resist, 2023, 16:4867-4879
Infect Drug Resist, 2023, 16:4867-4879
Ann Palliat Med, 2021, 10(2):1748-1754
S1399 Teicoplanin Teicoplanin (Teichomycin,Targocid,MDL-507) is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.
Front Microbiol, 2022, 13:884034
ACS Omega, 2022, 7(48):43657-43664
ACS Appl Mater Interfaces, 2020, 12(14):16150-16158
S1839 Chloroxine Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.
Biosensors (Basel), 2023, 13(6)571
Biosensors (Basel), 2023, 13(6)571
ACS Synth Biol, 2022, 11(8):2820-2828
S1502 Cephalexin Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections.
Clin Cancer Res, 2018, 24(3):659-673
Blood Cancer J, 2017, 10.1038/bcj.2017.61
Theranostics, 2017, 7(7):2092-2107
S2565 Amoxicillin Sodium Amoxicillin Sodium (Clavulanate,Amoxycillin sodium) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.
J Pharm Biomed Anal, 2022, 219:114904
ChemMedChem, 2022, e202200043
PLoS Comput Biol, 2020, 16(12):e1008489
S2575 Vancomycin HCl Vancomycin HCl is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent.
Front Microbiol, 2022, 13:884034
Elife, 2021, 10e64237
Gut Microbes, 2020, 12(1):1-20
S5492 Econazole Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.
Toxicol Appl Pharmacol, 2023, 475:116638
Acta Pharm Sin B, 2022, 12(7):3085-3102
Am J Cancer Res, 2020, 10(1):263-274
S1505 Aztreonam Aztreonam (SQ 26776) is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.
Antimicrob Agents Chemother, 2023, 10.1128/aac.00921-23
PLoS Pathog, 2016, 12(10):e1005932
Expert Opinion on Orphan Drugs, 2013, 1(7):549-556
S1677 Chloramphenicol Chloramphenicol (Chloromycetin) is a bacteriostatic by inhibiting protein synthesis.
Cell Rep, 2021, 34(3):108631
EMBO Rep, 2021, e53081
Oncotarget, 2018, 9(40):26086-26095
S4146 Bacitracin Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis.
Onco Targets Ther, 2020, 13:9543-9558
Anal Chem, 2017, 89(16):8501-8508
Chem Res Toxicol, 2017, 30(10):1804-1814
S4848 Dalbavancin Dalbavancin is a lipoglycopeptide antibiotic that has bactericidal activity against Gram-positive bacteria including various staphylococci.
Cell Rep, 2022, 39(11):110945
Front Microbiol, 2022, 13:884034
ACS Omega, 2022, 7(48):43657-43664
S4307 Auranofin Auranofin is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.
Cancers (Basel), 2024, 16(21)3606
Adv Healthc Mater, 2023, e2300591.
Theranostics, 2022, 12(12):5451-5469
S3121 Ornidazole Ornidazole (Ro7-0207, NSC 95075) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.
Biomedicines, 2023, 10.3390/biomedicines11092576
Biomedicines, 2023, 11(9)2576
Microorganisms, 2022, 10(7)1421
S1773 Oxytetracycline (Terramycin) Oxytetracycline(Terramycin) is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria.
Sci Rep, 2018, 8(1):7653
Front Microbiol, 2016, 7: 1765
S4004 Ethambutol 2HCl Ethambutol 2HCl (CL40881) is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
mBio, 2022, 13(4):e0167222
Molecules, 2019, 25(1)
S4093 Bismuth Subcitrate Potassium Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.
Cell Rep, 2022, 38(6):110359
J Clin Invest, 2020, 130(7):3901-3918
S3122 Amikacin hydrate Amikacin(BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections.
Microorganisms, 2022, 10(7)1421
Molecules, 2019, 25(1)
S4029 Colistin Sulfate Colistin (Polymixin E) is a cyclic cationic decapeptide linked to a fatty acid side chain, it belongs to a group of similarly structured bacterial antimicrobial peptides.
Front Pharmacol, 2021, 12:744494
Biogerontology, 2016, 17(5-6):907-920
S4148 Ampicillin Trihydrate Ampicillin Trihydrate (NCI-C56086,D-(-)-α-Aminobenzylpenicillin trihydrate) is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.
Front Vet Sci, 2022, 9:994652
Bone Joint Res, 2020, 16;9(4):152-161
S4959 Skatole Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.
Nutrients, 2023, 15(6)1490
Exp Cell Res, 2022, 421(1):113373
S5298 Amoxicillin trihydrate Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.
ChemMedChem, 2022, e202200043
PLoS Comput Biol, 2020, 16(12):e1008489
S4720 Cefotaxime Cefotaxime(HR-756) is a third-generation cephalosporin antibiotic and has broad spectrum activity against Gram positive and Gram negative bacteria.
Biosensors (Basel), 2024, 14(3)129
J Biol Chem, 2023, 299(6):104710
Carleton University, 2023, 10.22215/etd/2023-15364
S5440 Berberine Sulfate Berberine sulfate (Umbellatine), an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.
Front Pharmacol, 2021, 12:632201
Biology (Basel), 2021, 10(3)250
S4279 Demeclocycline HCl Demeclocycline HCl(Demeclocycline hydrochloride) is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.
J Biol Chem, 2020, 10.1074/jbc.RA119.011633.
Sci Rep, 2018, 8(1):7653
S5007 Delamanid Delamanid (OPC-67683) is a new anti-tuberculosis drug with an excellent intracellular bactericidal activity and a high accumulation rate.
Microbiol Spectr, 2023, e0046523.
Front Immunol, 2021, 12:796677
S4854 Bedaquiline fumarate Bedaquiline fumarate (TMC-207), an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.
Adv Healthc Mater, 2022, e2102117
Microorganisms, 2022, 10(7)1421
S2457 Clindamycin HCl Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
Proc Natl Acad Sci U S A, 2016, 113(50):14408-14413
S2568 Neomycin sulfate Neomycin sulfate(Framycin sulfate) is an aminoglycoside antibiotic, used to treat bacteria infections.
Mol Cell, 2020, 22 pii: S1097-2765(20)30231-8
S1855 Pefloxacin Mesylate Pefloxacin Mesylate(Pefloxacinium mesylate) is a synthetic chemotherapeutic agent and an antibacterial agent with IC50 of 6.7 nM.
Cellular and Molecular Biology, 2020,
J Biol Chem, 2019, 294(49):18624-18638
S1881 Protionamide Protionamide (Prothionamide, 1321-TH) is a drug used in the treatment of tuberculosis.
Mol Imaging Biol, 2021, 10.1007/s11307-021-01689-8
S5051 Pipemidic acid Pipemidic acid (Acido pipemidico) is a pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative bacteria including Pseudomonas aeruginosa and some gram-positive bacteria. Pipemidic acid is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA. It can be used for the research of intestinal, urinary, and biliary tract infections.
Hum Mol Genet, 2020, ddaa244
S5356 Ceftiofur Ceftiofur is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.
Vet J, 2018, 234:24-26
S5199 Oxytetracycline hydrochloride Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
Front Microbiol, 2016, 7:1765
S4490 Tetracycline Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.
PeerJ, 2022, 10:e13719
S5533 Tobramycin sulfate Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.
Oncotarget, 2018, 9(40):26086-26095
S5008 Ciprofloxacin (CPX) hydrochloride Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).
Nanomaterials (Basel), 2021, 11(8)1984
S2052 Oxytetracycline Dihydrate Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
Front Microbiol, 2016, 7:1765
S3496 Lefamulin acetate (Xenleta) Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.
J Biol Chem, 2022, 298(5):101909
S6549 PBTZ169 PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1.
Cell Death Dis, 2019, 10(4):319
S3655 Cefepime Dihydrochloride Monohydrate Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intra-abdominal infections.
ACS Chem Neurosci, 2021, 10.1021/acschemneuro.1c00608
S5330 Amikacin Sulfate Salt Amikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains.
Microorganisms, 2022, 10(7)1421
S4198 Aminothiazole Aminothiazole(2-Aminothiazole,2-Thiazolylamine) can be used as a thyroid inhibitor and it has antibacterial activity.
J Electroanal Chem (Lausanne), 2020, 878:114733
S3709 Furagin Furagin (NF-416, F-35, Akritoin, Furazidin, Furazidine) is 2-substituted 5-nitrofuran, chemically and structurally similar to well-known antibacterial compound nitrofurantoin with antimicrobial activities.
J Clin Med, 2023, 12(16)5166
J Clin Med, 2023, 12(16)5166
S4203 Furaltadone HCl Furaltadone HCl(Altafur hydrochloride) is an antibacterial and has distinct curative effect in the treatment of coccidiosis.
Eur J Pharmacol, 2018, 828:119-125
S6411 Nimorazole Nimorazole is a water soluble, 5-nitroimidazole compound with antibacterial and potential radiosensitizing activity.
Microorganisms, 2022, 10(7)1421
S3802 Trigonelline Hydrochloride Trigonelline (Nicotinic acid N-methylbetaine, Coffearine, Gynesine), a major alkaloid component of fenugreek, has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and also has been shown to reduce diabetic auditory neuropathy and platelet aggregation.
Respir Res, 2024, 25(1):242
Biomed Pharmacother, 2021, 143:112204
S5047 Methyl α-D-mannopyranoside Methyl α-D-mannopyranoside can be used as an intermediate for chemical sythesis and is a competitor inhibitor of the binding of mannose by Escherichia coli.
mBio, 2022, e0217721
S5410 Chloramphenicol sodium succinate Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.
Oncotarget, 2018, 9(40):26086-26095
S5208 Ciprofloxacin hydrochloride hydrate Ciprofloxacin Hydrochloride (Ciloxan, Ceprimax, Oftacilox,Bay-09867 hydrochloride hydrate) is the hydrochloride salt form of ciprofloxacin, which is an antibiotic used to treat a number of bacterial infections.
Heliyon, 2024, 10(11):e32571
Nanomaterials (Basel), 2021, 11(8)1984
S3065 Amikacin disulfate Amikacin sulfate (BB-K8) binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.
Microorganisms, 2022, 10(7)1421
S4528 Furazolidone Furazolidone(Furoxone) is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria.
Kaohsiung J Med Sci, 2020, 10.1002/kjm2.12281
S4536 Nitrofurantoin Nitrofurantoin (Macrodantin, Furadantine, Furadonine) is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis.
J Clin Med, 2023, 12(16)5166
J Clin Med, 2023, 12(16)5166
S9135 Artemisic acid Artemisic acid (Artemisinic acid), an amorphane sesquiterpene isolated from Artemisia annua L., has a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect.
ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S0906 6-Methoxydihydrosanguinarine 6-Methoxydihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata. 6-Methoxydihydrosanguinarine shows strong cytotoxicity against MCF-7 and SF-268 cell lines with IC50 values of 0.61 μM and 0.54 μM, respectively.
Phytomedicine, 2022, 102:154164
S1162 Pretomanid (PA-824) PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.
S1370 Biapenem Biapenem (L-627, LJC10627) is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains.
S1768 Cefditoren Pivoxil Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.
S1605 Cefdinir Cefdinir (FK 482, PD 134393, CI-983) is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body.
Cancers (Basel), 2023, 15(8)2373
S2544 Cefprozil hydrate Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin antibiotic, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin.
S2563 Oxacillin sodium monohydrate Oxacillin sodium monohydrate (Methicillin) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
S3129 Trimethoprim Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
Cell Rep, 2024, 43(7):114500
Sci Rep, 2024, 14(1):9167
Sci Rep, 2024, 14(1):9167
S1915 Sulfamethoxazole Sulfamethoxazole(Ro 4-2130) is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.
S1762 Pyrazinamide Pyrazinamide (Pyrazinoic Acid Amide) is an agent used to treat tuberculosis.
S1791 Bacitracin Zinc Bacitracin(Zinc Bacitracin) is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
S2543 Ceftiofur HCl Ceftiofur HCl (U-67279A,Excenel hydrochloride) is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.
S1916 Sulfisoxazole Sulfisoxazole (NU-445) is a sulfonamide antibacterial with an oxazole substituent.
S3195 Azlocillin sodium salt Azlocillin is an acylampicillin with a broad spectrum against bacteria.
S1618 Sulfameter Sulfameter is a long-acting sulfonamide antibacterial.
S1957 Sulfamethizole Sulfamethizole is a sulfathiazole antibacterial agent.
S3133 Sulfamethazine Sulfamethazine(Sulfadimidine,Sulfadimerazine) is a sulfonamide antibacterial.
S1685 Sulfanilamide Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
S3179 Carbenicillin disodium Carbenicillin (BRL-2064,α-carboxybenzylpenicillin) is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.
S3193 Ticarcillin sodium Ticarcillin (AB 2288, BRL 2288) is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
E2970 Gramicidin Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is an antimicrobial peptide that destroys gram-positive bacteria. It inhibits the growth of bacteria by forming pores and channels in the cell wall, which increase its permeability to monovalent cations.
S5227 Erythromycin thiocyanate Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
E3812 Rhamnus Cathartica Extract Rhamnus Cathartica Extract is extracted from Rhamnus cathartica, which has antimicrobial activity.
S5352 Cefminox Sodium Cefminox Sodium (Meicelin, MT-141) is the sodium salt form of cefminox, a semi-synthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity.
S6235 Sodium dehydroacetate Sodium dehydroacetate is the sodium salt of dehydroacetic acid, a fungicide and bactericide that is commonly used as a food preservative. Sodium dehydroacetate is a preservative that is used in the formulation of cosmetics and personal care products in order to extend the shelf-life by preventing microbial contamination.
S3621 Pazufloxacin mesylate Pazufloxacin Mesylate (T-3762, Pazucross), also known as Pazucross and T-3762, is a quinolone antibacterial agent used for the intravenous therapy of several infections.
E3040 Stemonae Extract Stemonae Extract is extracted from Radix Stemonae, has been widely used as an oral anti-tussive agent in traditional Chinese medicine (TCM) for thousands of years with pharmacological effects as anti-tussive, anti-tuberculous, anti-bacterial, anti-fungal and anti-helminthic.
S5560 Midecamycin Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
S5105 Proanthocyanidins Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxygen radicals from cells.
Viruses, 2022, 14(2)353
Viruses, 2022, 14(4)764
S5406 Sultamicillin Tosylate Sultamicillin Tosylate is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant.
E3820 Leonurus Japonicus Extract Leonurus Japonicus Extract is extracted from Leonurus japonicus, which has anti-bacterial, anti-cancer, and liver protection activities.
S5048 Fosfomycin Disodium Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.
E3047 Isatis Extract Isatis Extract is drawed from Baphicacanthus cusia, might be able to fight bacteria and viruses that can cause infections, reduce fever and swelling, also might keep cancer cells from multiplying.
S4576 Sulfabenzamide Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) is an antibacterial/antimicrobial which also exhibit their antitumor effects through multiple mechanisms including inhibition of membrane bound carbonic anhydrases, prevention of microtubule assembly, cell cycle arrest, and inhibition of angiogenesis.
S5353 Cefpiramide sodium Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.
S5081 Ceforanide Ceforanide is a new cephalosporin with antibacterial activity and has a longer elimination half-life than any currently available cephalosporin.
S5951 Cefoxitin Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
S3295 Taxifolin 7-rhamnoside Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside), a flavonoid isolated from Hypericum japonicum, shows antibacterial activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
E3051 Scutellaria Barbata Extract Scutellaria Barbata Extract is drawed from Scutellaria barbata; Scutellaria barbata nanoparticles (Sb-AgNP) effectively inhibits the biofilm formation and possesses antimicrobial property against skin infection causing microbes.
E3537 Apple cider vinegar Extract Apple Cider Vinegar Extract is extracted from apple cider vinegar, which has antimicrobial activity.
S2596 Clindamycin palmitate HCl Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.
E3046 Patriniae Extract Patriniae Extract is extracted from Patrinia scabiosaefolia or Patrinia villosa, is able to significantly reduce the biofilm formation and dramatically alters the structure of the mature biofilms of Pseudomonas aeruginosa.
E3538 Apple Extract Apple Extract is extracted from Malus, which has an anti-cariogenic effect on S. mutans and aids in the prevention of dental caries.
S5012 Octenidine Dihydrochloride Octenidine, a cationic surfactant, is active against gram-positive and gram-negative bacteria.
E3541 Grapefruit Seed Extract Grapefruit Seed Extract is extracted from the seeds of Citrus paradisi Macf., which can be used as an anti-biofilm agent that is effective against S. aureus and E. coli.
E3545 Pu-erh tea Extract Pu-erh tea Extract is the aqueous extract Pu-erh tea, which can alleviate the intestinal inflammation caused by antibiotics, reduce the degree of intestinal lesions, promote the growth of intestinal probiotics and inhibit pathogenic bacteria.
E3548 Chia seed Extract Chia Seed Extract is extracted from the seed of Salvia Hispanica, which contain a highly stable trypsin inhibitor with potential for bacterial management alone or in drug combination therapy with oxacillin.
S2830 Clindamycin Clindamycin inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
S3623 Ceftibuten dihydrate Ceftibuten Dihydrate(Sch-39720 dihydrate) is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity.
S4850 Flucloxacillin sodium Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
S9224 Dehydroandrographolide Succinate Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.
S4846 Meropenem Trihydrate Meropenem is a broad-spectrum antibacterial agent of the carbapenem family with a broad spectrum of in vitro activity against Gram-positive and Gram-negative pathogens.
S9226 Steviolbioside Steviolbioside (CCRIS-6025), a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
S4594 Cephalothin sodium Cephalothin (Cefalotin, Cephalotin) sodium is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.
S5941 Besifloxacin Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis.
S3703 Phenethyl alcohol Phenethyl alcohol (2-phenylethanol, 2-Phenylethyl alcohol, Benzeneethanol, Phenylethanol) is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
S5186 Cefpiramide Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) is a pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
E3077 Tsaoko Fructus Extract Tsaoko Fructus Extract is extracted from Tsaoko Fructus, which has antibacterial properties.
S4880 Cefathiamidine Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
S5268 Solithromycin Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
Nat Commun, 2024, 15(1):6579
S0534 PK150 PK150 is an analogue of Sorafenib, which shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively.
S1617 Sulfapyridine Sulfapyridine is a sulfonamide antibacterial.
S5332 Cefquinome sulfate Cefquinome sulphate is a veterinary, parenteral, and fourth-generation cephalosporin. Its antimicrobial potency and extensive antibacterial spectrum result from the introduction of a methoxyimino-aminothiazolyl moiety into the acyl side chain.
S5278 Tedizolid Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
E0365 Fucoidan

Fucoidan is an anionic sulfated polysaccharide extracted from marine brown algae with a large range of biological activities, including anti-inflammatory, anti-cancer, anti-viral, anti-oxidation, anticoagulant, antithrombotic, anti-angiogenic and anti-Helicobacter pylori, etc.

Int J Biol Macromol, 2024, 276(Pt 1):133792
S5532 Erythromycin estolate Erythromycin (Lubomycine B), a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S5495 Ceftiofur sodium Ceftiofur sodium is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.
S5625 Ammonium lactate Ammonium lactate (Lac-hydrin) is the ammonium salt of lactic acid with mild anti-bacterial properties.
S4869 Sulfamethoxazole sodium Sulfamethoxazole sodium is an antibiotic used for bacterial infections.
S5054 Rifamycin sodium salt Rifamycin sodium is an antibacterial drug used for treatment of mycobacterium infections.
S3499 Monocaprylin Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) exhibits an excellent antibacterial activity against Staphylococcus aureus and Escherichia coli.
S5491 Lomefloxacin Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic used to treat bacterial infections.
E3107 Andrographis Herba Extract Andrographis Herba Extract is obtained from the aerial part of Andrographis paniculata (Burm. F.) Nees, has various activities including antimicrobial and antioxidant, antimalarial, antiangiogenic, anti-inflammatory, anti-diabetic, and in vitro α-glucosidase and α-amylase enzyme inhibitory activities.
E3236 Champion Wood Fern Extract Champion Wood Fern Extract is extracted from Dryopteris championii, which has antibacterial activities.
S5331 Ceftezole sodium Ceftezole Sodium (Celoslin sodium, Falomesin sodium) is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity.
S4595 Cefazolin Sodium Cefazolin Sodium (cefazoline, cephazolin, Ancef) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
S5936 Cefazolin Cefazolin(Cephazolin) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
S4596 Cefixime Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.
S7550 Erythromycin Cyclocarbonate Erythromycin Cyclocarbonate(Davercin), derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.
S4875 Cephapirin Benzathine Cephapirin Benzathine is the benzathine salt form of cephapirin, which is a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity.
S4885 Taurolidine Taurolidine (Taurolin, Tauroline, Tauroflex) is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities.
S4861 Oxindole Oxindole (2-indolone, 2-Oxindole, Indolin-2-one) is an aromatic heterocyclic organic compound which causes sedation, muscle weakness, hypotension, and coma when dosed in excess. Oxindole has anti-cancer, anti-HIV, anti-diabetic, antibacterial and other pharmacological activities.
E3251 Tropaeolum Majus Extract Tropaeolum Majus Extract is extracted from Tropaeolum majus, which acts against bacterial infections and reduces apoptosis and DNA lesions in hypertonic conditions.
S3142 Potassium sorbate

Potassium sorbate (Sorbic acid potassium) is a nonpoisonous food preservative isolated from Sorbus aucuparia. Potassium sorbate is an effective inhibitor of most molds and yeasts and some bacteria.

E0010 Hypocrellin A Hypocrellin A (HA) is a perylenequinone isolated from Shiraia bambusicola that shows antiviral, antimicrobial and anticancer activity through mediating multiple signaling pathways. Hypocrellin A also is a selective and potent inhibitor of PKC.
E4983New Omadacycline hydrochloride Omadacycline hydrochloride (PTK0796 hydrochloride) is a first-in-class orally active member of the tetracycline class of antibiotics. Omadacycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride exhibits broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria.
E3611 Camellia japonica Extract Camellia Japonica Extract is extracted from the flowers of Camellia japonica L.. Camellia japonica possesses antimicrobial, antioxidant and antitumoral activity and as being a huge source of polyphenols such as the catechins.
E3612 Cremastra appendiculata Extract Cremastra Appendiculata Extract is extracted from Cremastra appendiculata (Pseudobulbus Cremastrae seu Pleiones), the dried pseudostem of plants of the Orchidaceae family. Cremastra appendiculata has antibacterial, antihypertensive, gout, antitumor, and acetylcholine receptor M3-blocking effects. The extract of cremastra appendiculata can be used to treat Lewis lung cancer, liver cancer, and breast cancer.
S4647 Cefmenoxime hydrochloride Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.
S4874 Cefazedone Cefazedone (Refosporen, Cefazedonum) is a semisynthetic first-generation cephalosporin with antibacterial activity.
S6867 Glyceryl monocaprate (Monocaprin) Monocaprin (Glyceryl caprate) is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.
E3614 Arnica montana Extract Arnica Montana Extract is extracted from the flowers of Arnica montana L. (Asteraceae). Arnica montana possesses anti-inflammatory, immune-modulatory, anti-sclerotic, analgesic, antifungal, antioxidant, antibacterial, and anticancer bioactivities.
S4602 Acetohydroxamic acid Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
S0715 ML406 ML406 is a small molecule probe that shows anti-tubercular activity via M.tuberculosis BioA (DAPA synthase) enzyme inhibition with an IC50 of 30 nM.
E3262 Walnut Leave Extract Walnut Leave Extract is extracted from the leaves of Juglans, which has both anti-bacterial and anti-parasitic properties.
S9466 Methenamine Hippurate Methenamine Hippurate is the hippurate salt form of methenamine, a prodrug and inactive weak base that is hydrolyzed to formaldehyde in acid urine.Methenamine Hippurate is the component of Hiprex drug which has antibacterial activity.
S9292 Dictamnine Dictamnine, a natural plant product, has been reported to have antimicrobial activity against bacteria and fungi.
S5296 Cephradine monohydrate Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
S5487 Cefoperazone sodium Cefoperazone Sodium(CP 52640-2) is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
S4822 Silver Sulfadiazine Silver sulfadiazine is a bactericidal for many gram- negative and gram-positive bacteria as well as being effective against yeast.
S5736 Benzathine penicilline Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections.
E3621 Crataegi fructus Extract Crataegi Fructus Extract is extracted from the fruits of Crataegi fructus (hawthorn). Crataegi fructus is dry ripe fruit of Crataegus pinnatifida Bge.var. major N. E. Br. or Crataegus pinnatifida Bge.. The extracts and compounds from fructus crataegi show a variety of pharmacological activities, such as a protective effect on patients with heart failure, as well as an increased force of myocardial contraction, improved coronary circulation, antioxidant effects and antimicrobial activities.
S1884 Sparfloxacin Sparfloxacin (AT-4140, CI-978, PD 131501,Zagam) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.
E3735 Ficus hirta Vahl Extract Ficus Hirta Vahl Extract is derived from Ficus hirta Vahl. (Wuzhimaotao), which possesses hepatoprotective, antibacterial, and anti-inflammatory bioactivities and improves memory function of AD mice.
S2385 Hordenine Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
S4634 Sodium sulfadiazine Sodium Sulfadiazine (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.
S5291 sulfaisodimidine Sulfaisodimidine (Sulfamethin) is a sulfonamide antibacterial.
S5235 Cefodizime Cefodizime (CEF, CDZ) is an aminothiazolyl cephalosporin with a broad spectrum of antibacterial activity.
S5417 Spectinomycin dihydrochloride pentahydrate Spectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome.
S3644 Sulfamonomethoxine Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
S5546 Sulfacetamide Sulfacetamide (Acetosulfamine) is a synthetic sulfanylacetamide derivative with bacteriostatic activity. It is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
S4179 Mezlocillin Sodium Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.
S4060 Erythromycin Ethylsuccinate Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
S5515 Penicillin G Procaine Procaine benzylpenicillin (Procaine benzylpenicillin,PGP), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
S5289 Ceftezole Ceftezole (Celoslin, Falomesin) is a semi-synthetic first-generation cephalosporin with antibacterial activity.
S6872 Merbromin Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the KM and decreasing the Kcat of 3CLpro.
E4867New Omadacycline Omadacycline(Amadacycline) is an oral aminomethylcycline antibacterial antibiotic used to treat moderate-to-severe infections, such as community-acquired pneumonia and acute bacterial skin and skin structure infections caused by susceptible organisms. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline has broad-spectrum antibacterial activity and is effective against Gram-positive and Gram-negative aerobic, anaerobic, and atypical bacteria.
S5637 Cefotiam Hexetil Hydrochloride Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.
S5638 Cefozopran hydrochloride Cefozopran Hydrochloride is the hydrochloride salt form of cefozopran, a semi-synthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity.
S5644 Ceftriaxone Sodium Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.
Biosensors (Basel), 2024, 14(3)129
S8871 Omadacycline tosylate Omadacycline tosylate(PTK 0796 tosylate,Amadacycline tosylate) is a first-in-class aminomethylcycline antibiotic, demonstrating antimicrobial activity in vitro against a range of Gram-positive and Gram-negative aerobes and some anaerobic bacteria.
S5420 Clindamycin alcoholate Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
E3297 Fenugreek Seed Extract Fenugreek Seed Extract is extracted from the seeds of Trigonella foenum-graecum, which acts as an antibacterial and anticancer agent.
S4750 Sulfacetamide sodium salt hydrate Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.
S6584 Amdinocillin Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms.
E3353 Acacia Farnesiana Extract Acacia Farnesiana Extract is extrcated from Acacia Farnesiana, which acts against M. tuberculosis and dysentery bacteria.
E0052 Merafloxacin Merafloxacin (CI-934) is a fluoroquinolone antibacterial thats inhibit -1 frameshifting efficiency of SARS-CoV-2 and other betacoronaviruses.
E6017New Ornidazole (Levo-) Ornidazole (Levo-) (Levornidazole, (S)-Ornidazole), the levo-isomer of ornidazole, is a third-generation nitroimidazole derivative. It exhibits antiprotozoal and antibacterial properties against anaerobic bacteria.
S3636 Cefadroxil hydrate Cefadroxil(BL-S 578 hydrate) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
S3637 Cefpirome sulfate Cefpirome(HR-810 sulfate) is a fourth-generation cephalosporin and is considered highly active against Gram-negative bacteria.
E3388 Latifolin Extract Ilex kudingcha C.J. Tseng Extract is obtained from Ilex kudingcha C.J. Tseng, which possesses a broad range of pharmacological properties, including antioxidant, hepatoprotectant, antibacterial, antihistaminic, anticancer, neuroprotective and other biological effects.
S3638 Cefamandole nafate Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
S3350 Cholesteryl linoleate

Cholesteryl linoleate is less polar lipid in human nasal fluid that contributes to the inherent antibacterial activity.

E3398 Sunflower dish Extract Sunflower dish Extract is extracted from Helianthus, which contains antioxidant, antimicrobial, anti-proliferative, and DNA protective activities.
S0147 KKL-10 KKL-10 is an inhibitor of ribosome rescue that exhibits exceptional broad-spectrum antimicrobial activity against bacteria.
S4983 Sorbic acid Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S0843 Filastatin Filastatin, a long-lasting inhibitor of Candida albicans filamentation, inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay.
S3708 Sulfachloropyridazine Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections.
S4201 Florfenicol Florfenicol (SCH-25298,(-)-Florfenicol) is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.
S4663 Fusidate Sodium Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
S3710 Fosfomycin calcium Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
S4986 Latamoxef sodium Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects.
S6031 2,6-Dihydroxybenzoic acid 2,6-Dihydroxybenzoic acid (γ-resorcylic acid, 2-Carboxyresorcinol, 2,6-Resorcylic acid) is a phenolic compound which is known to have poor biological performance such as DPPH scavenging activity and microbial growth inhibition.
S5166 Benzoyleneurea Benzoyleneurea (2,4-Dihydroxyquinazoline, Quinazolinedione, Quinazoline-2,4-diol) scaffold is used in the synthesis of novel protein geranylgeranyltransferase-I inhibitors. Benzoyleneurea possesses anti-bacterial activity.
S3058 Danofloxacin Mesylate Danofloxacin (CP-76136-27) is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM.
S4271 Isepamicin Sulphate Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.
S3672 Cefonicid sodium Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.
S6090 JFD01307SC JFD01307SC ([(1,1-dioxidotetrahydrothien-3-yl)amino]acetic acid) shows activity against M.tuberculosis with minimum inhibitory concentrations (MICs) in the range of 8 to 16 µg/ml. JFD01307SC may targets enzymes involved in glutamine biosynthesis.
E3695 Hypericum japonicum Extract Hypericum Japonicum Extract is obtained from the entire herb of Hypericum japonicum, has been widely used for the treatment of bacterial diseases, infectious hepatitis, acute and chronic hepatitis, gastrointestinal disorder, internal hemorrhage and tumour.
S4213 Dirithromycin Dirithromycin (LY-237216, ASE 136,Dynabac) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.
E3696 Panax notoginseng Extract Panax notoginseng Extract is is made from the dry roots of Panax notoginseng, which is used to treat inflammation and bleeding, also inhibits Streptococcus pyogenes without affecting oral commensal bacteria.
E4353 Ampicillin Ampicillin (D-(-)-alpha-Aminobenzylpenicillin) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. It exhibits a good minimum inhibitory concentration for Staphylococcus aureus, Escherichia coli, Hemophilus influenzae, and Streptococcus pneumoniae with MICs of 0.6–1 mg/L, 4 mg/L, 0.25 mg/L, and 0.03-0.06 mg/L, respectively.
S4216 Valnemulin HCl Valnemulin HCl is a broad-spectrum bacteriostatic agent inhibiting protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.
Int Immunopharmacol, 2024, 141:112810
E3420 Trumpet creeper Extract Trumpet creeper Extract is extracted from Campsis, which has antibacterial and antifungal properties.
E0828 Mitonafide Mitonafide inhibits the activity of Mycobacterium tuberculosis NAD+ dependent DNA ligase A at concentrations of 50 µM. 
E0816 Oritavancin Diphosphate Oritavancin Diphosphate is an orally active glycopeptide antibiotic which is active against Gram-positive bacteria and also has antibacterial activity against multidrug-resistant Streptococcus pneumoniae.
S4105 Closantel Sodium Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S5070 Mupirocin calcium Mupirocin Calcium (Pseudomonic acid A) is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic.
S4106 Closantel Closantel (R-31520,nsc 335306) is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
J Fungi (Basel), 2024, 10(2)131
S3712 Tulathromycin A Tulathromycin A is a novel long-acting semi-synthetic tribasic macrocyclic antibiotic of the triamilide group and used for the treatment of pulmonary diseases of swine and cattle.
S6067 2,4-dichlorobenzyl alcohol 2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections.
E3707 Chenopodium ambrosioides Extract Chenopodium Ambrosioides Extract is obtained from Chenopodium ambrosioides Linn. (Chenopodiaceae), which has insecticidal and antimicrobial potency.
S9099 Orientin Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
E3128 Isatidis Folium Extract Isatidis Folium Extract is obtained from the dry leaves of Isatis indigotica Fort. (family Cruciferae), has been commonly applied in orient countries for centuries as antipyretic, antiviral, anti-inflammatory, anti-influenza, and anti-cancer agents.
S5776 Proflavine Proflavine (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria. It is a topical antiseptic used mainly in wound dressings.
S6444 Triclocarban Triclocarban is an antibacterial agent common used in personal care products.
S3650 Penicillin V potassium salt Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
E3134 Sphaeranthus Africanus Extract Sphaeranthus Africanus Extract is obtained from Sphaeranthus africanus, of which carvotacetones show antimycobacterial effects.
S0423 GSK2200150A GSK2200150A is identified by high-throughput screening (HTS) campaign that can be used as an anti-tuberculosis (TB) agent (MIC = 0.38 µM).
S9328 5,6,7-Trimethoxyflavone 5,6,7-Trimethoxyflavone (Baicalein Trimethyl Ether), methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.
E3138 Lophatheri Herba Extract Lophatheri Herba Extract is drawed from Herba Lophatheri, which enhances the moisture and oil resistance, antioxidant activity that declines with time, and antimicrobial activity of the chitosan film.
E3723 Lindera aggregata leaves Extract Lindera Aggregata Leaves Extract is derived from the leaves of Lindera aggregate (Sims) Kosterm., which have a wide spectrum of biological effects, including antioxidant, antibacterial, liver and cardiovascular protection.
E2952 2-Chloroacetamide 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase.
S6464 Ftaxilide Ftaxilide is a novel antituberculosis agent.
S5924 Olanexidine Hydrochloride semihydrate Olanexidine (OPB-2045, OPB-2045G) is a monobiguanide compound with bactericidal activity.
E3740 Isodon serra Extract Isodon Serra Extract is obtained from Isodon serra (Maxim.) Hara, which processes antitumour, anti-angiogenic, analgesic, antitubercular, anti-inflammatory, antibacterial and anti-ischemic activities.
S0195 Walrycin B Walrycin B is an antibacterial compound and a potent inhibitor of WalR targeting the WalR response regulator.
S4517 Cefotaxime sodium Cefotaxime sodium(HR-756) salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.
Biosensors (Basel), 2024, 14(3)129
S9122 Tectorigenin Tectorigenin (TEC) is an isoflavone isolated from various medicinal plants, such as Pueraria thunbergiana Benth, Belamcanda chinensis, and Iris unguicularis. It has been reported to exert pharmacological actions, including antitumor and antibacterial effects, free radical neutralization, and selective estrogen receptor modulation.
S4518 Chloroxylenol Chloroxylenol is a broad-spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.
S5209 Enoxacin Sesquihydrate Enoxacin sesquihydrate (Enoxacin hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
S9377 Eugenyl acetate Eugenyl acetate, an aromatic component of clove essential oil, exhibits various pharmacological activities, including antibacterial and anti-virulence activities against drug-resistant A. baumannii clinical isolates.
E3158 Caryophylli Flos Flower Extract Caryophylli Flos Flower Extract is extracted from the flower of Caryophylli Flos, which can be used in treatment for diabetic foot ulcer therapy since it improves diabetic wound healing and exerts antibacterial activity.
S3132 Sulfamerazine Sulfamerazine (RP 2632,sulphamerazine) is a sulfonamide antibacterial.
S4523 Dihydrostreptomycin sulfate Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep. Dihydrostreptomycin is a derivative of streptomycin.
S5473 Pivmecillinam hydrochloride Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.
S5202 Quinocetone Quinocetone is a novel veterinary chemicals that is also bacteriocide and potential anti-tumor agent.
S4780 7-Methoxy-4-methylcoumarin 7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label. 7-Methoxy-4-methylcoumarin has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 of 11.76 μg/ml and 13.47 μg/ml, respectively.
S5201 Acetylisovaleryltylosin Tartrate Acetylisovaleryltylosin tartrate (AK105039) is an antimicrobial of the macrolide group with antibacterial activity against Gram-positive bacteria.
E3165 Rabdosiae Rubescentis Herba Extract Rabdosiae Rubescentis Herba Extract is drawed from the dried aerial part of genus Rabdosia rubescens (Hemsl.) Hara of the Lamiaceae family, which possesses several biological activities, such as anti-bacteria, anti-parasites, anti-inflammation, and anticancer.
S5211 4-Aminosalicylic acid 4-Aminosalicylic acid (Para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate) is an antitubercular agent with bacteriostatic activity against Mycobacterium tuberculosis.
E3755 Cyperus Rotundus Extract Cyperus Rotundus Extract is drawed from Cyperus rotundus L., which exerts phytochemical, antimicrobial, antioxidant and antigenotoxic potentials.
S4833 Cefoxitin sodium Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
E4939New Sulfisoxazole acetyl Sulfisoxazole acetyl(N1-Acetylsulfisoxazole, Acetyl sulfafurazole), a sulfisoxazole derivative, is an orally active inhibitor of dihydropteroate synthase. Sulfisoxazole acetyl can be biotransformed primarily to sulfisoxazole, and partly to N(4)-acetyl sulfisoxazole (N4AS). Sulfisoxazole acetyl exhibits antibacterial action.
E3760 Cymbopogon Citratus Extract Cymbopogon Citratus Extract is derived from Cymbopogon citratus DC (Stapf.), which has antimicrobial, antiprotozoal, anti-rheumatic, antitumoural, cardio-protective, anti-inflammatory and gastroprotective properties.
S9136 Neochlorogenic acid Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.
Biomacromolecules, 2024, 25(2):729-740
E3761 Elsholtzia Ciliata Extract Elsholtzia Ciliata Extract is obtained from Elsholtzia ciliata (Thunb.) Hyl.—an annual plant belonging to Lamiaceae Martinov family, which possesses anti-inflammatory, antiviral, antibacterial, antioxidant, anticancer, and vasorelaxant effects.
S5350 Cefpodoxime proxetil Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.
S5095 Olaquindox Olaquindox (Bisergon, Bayernox, Bayonox, Olachindox) is an oral anti-bacterial agent used as an additive to animal food.
E3771 Millet Extract Millet Extract is derived from millet, which is the primary source of dietary fiber and polyphenols, which offers several health benefits such as antidiabetic, antioxidant, hypocholesterolemic, antimicrobial, and protective effects against diet-related chronic diseases.
E3772 Eyebright Extract Eyebright Extract is extracted from Herba Euphrasiae (Scrophulariaceae), which includes anti-inflammatory, antioxidant, antimicrobial, anticancer, antifungal, antiviral, hypotensive, hapatoprotector, anti-epileptic, and anti-catarrhal activities.
S4544 Urethane Urethane (Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane) is a kind of antineoplastic agent that is also used as a veterinary anesthetic. It is a intermediate in organic synthesis.
DSpace, 2023, Volume 30 Issue 11
E4954New Demeclocycline Demeclocycline(Demethylchlortetracycline (DMCT), Ledermycin) is a bacteriostatic antibiotic from the tetracycline class, that induces diuresis and can cause nephrogenic diabetes insipidus. It also manages the syndrome of inappropriate antidiuretic hormone secretion (SIADH) by restoring normal plasma sodium levels and permitting unrestricted water intake.
E3782 Arctostaphylos Uva Ursi Leaf Extract Arctostaphylos Uva Ursi Leaf Extract is drawed from the Arctostaphylos uva-ursi leaf, which could represent a natural product to counter the virulence of Cutibacterium acnes, representing a new alternative therapeutic option for the treatment of acne vulgaris.
S4425 Rifamycin S Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.
S4813 Cefuroxime axetil Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
S4436 Pleuromutilin Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
S4393 Cephapirin Sodium Cephapirin Sodium (Cefapirin) is the sodium salt form of cephapirin, a semi-synthetic, first-generation cephalosporin antibiotic with bactericidal activity.Cephapirin Sodium is effective against gram-negative and gram-positive organisms.
S4547 8-Hydroxyquinoline 8-Hydroxyquinoline (8-Oxychinolin, 8-Quinolinol, Oxine) is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes.
S5354 Cefteram pivoxil Cefteram Pivoxil is the pivalate ester prodrug of cefteram, a semi-synthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity.
S3280 Linderene Linderene (Lindenenol) is a furanosesquiterpenoid isolated from Lindera pulcherrima with antibacterial and antioxidant activities.
S4550 Azelaic acid Azelaic acid (Nonanedioic acid, Finacea, Azelex, Anchoic acid) is an organic compound produced by the ozonolysis of oleic acid and possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity.
S4844 Cefcapene Pivoxil Hydrochloride Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity.
E3791 Surgentodoxa Cuneata Extract Surgentodoxa Cuneata Extract is drawed from Surgentodoxa Cuneata, which has anti-inflammatory, antioxidant, antitumor, antimicrobial, and anti-sepsis activities.
E3469 Cranberry Extract Cranberry Extract is extracted from Vaccinium macrocarpon, which has beneficial effects against urinary tract infections.
E0515 Cefatrizine Cefatrizine, a broad-spectrum, semisynthetic, first-generation cephalosporin with antibacterial activity, binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
S4553 Bronopol Bronopol (2-bromo-2-nitropropane-1,3-diol) is antibacterial agent, used as preservative in cosmetic industry.
S7739 Telacebec Telacebec is a novel antituberculosis drug that targets Mycobacterium tuberculosis cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. Telacebec (Q203, IAP6) is active against Mycobacterium tuberculosis H37Rv with MIC50 of 2.7 nM in culture broth medium.
S5863 Metronidazole Benzoate Metronidazole Benzoate (Benzoyl metronidazole) is the benzoate ester of metronidazole, a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
S4404 Pasiniazid Pasiniazid(Paraniazide,Pasiniazide) is a composition of isoniazid and 4-aminosalicylic acid, used to treat tuberculosis patients.
E3510 Costustoot Extract Costustoot Extract is extracted from the roots of costus, which has antibacterial properties and serves an inhibitory role in the regeneration of gut bacteria.
S4522 Dehydroacetic acid Dehydroacetic acid (Biocide 470F, Methylacetopyronone) is an organic compound, used mostly as a fungicide and bactericide.
E3802 Inula Cappa Extract Inula Cappa Extract is drawed from Inula Cappa, which has many biological activities and exerts anti-inflammatory, analgesic, antibacterial, antitumor, antioxidant, and immunomodulatory effects.
S4408 Procodazole Procodazole (Propazol, 2-Benzimidazolepropionic acid, 3-(1H-benzimidazole-2) propanoic acid) is used as a potentiator which is non-specific active immunoprotective against viral and bacterial infections.
E3514 Burdock root Extract Burdock Root Extract is extracted from the roots of Arctium, which exhibits antibiofilm activity.
E3806 Allium Cepa Extract Allium Cepa Extract is drawed from Allium cepa Linnaeus, which has hypoglycaemic, anti-diabetic, hypolipidemic and antimicrobial functions.
S4565 Diiodohydroxyquinoline Diiodohydroxyquinoline (Iodoquinol) is a topical therapeutic agent,a quinoline derivative, with satisfactory antibacterial properties.
S5456 Isobavachalcone Isobavachalcone (Corylifolinin), a naturally occurring chalcone compound derived from the seeds of Psoralea corylifolia L., has long been used in traditional Chinese medicine as anthelmintic, antibacterial, aphrodisiac, astringent and antiplatelet agent.
E3810 Bauhinia Variegata Extract Bauhinia Variegata Extract is drawed from Bauhinia variegata L., which has antibacterial, antioxidant, anti-inflammatory and anticarcinogenic effects.
E3520 Goose Grass Extract Goose Grass Extract is isolated from Eleusine indica, which displays antioxidant, antimicrobial and anticancer activities.
S2908 Hygromycin B Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.
Redox Biol, 2024, 76:103349
Front Pharmacol, 2024, 15:1432851
Cell Death Dis, 2023, 14(6):348
S3021 Rimonabant (SR141716) Rimonabant (SR141716) is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.
Toxicol Lett, 2023, 374:48-56
Int J Biol Sci, 2022, 18(4):1401-1414
Mol Metab, 2022, 65:101597
S7894 Tunicamycin Tunicamycin, an antibiotic, can potently inhibit the N-linked glycosylation (NLG) by competitively inhibiting UDP-GlcNAc-dolichol-phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) activity and can target several types of tumors by reducing angiogenesis, inhibiting colony formation, and enhancing TRAIL-induced apoptosis.
Cell Discov, 2023, 9(1):92
Cell Discov, 2023, 9(1):92
Adv Sci (Weinh), 2023, 10(25):e2300414
S1677 Chloramphenicol Chloramphenicol (Chloromycetin) is a bacteriostatic by inhibiting protein synthesis.
Cell Rep, 2021, 34(3):108631
EMBO Rep, 2021, e53081
Oncotarget, 2018, 9(40):26086-26095
S4307 Auranofin Auranofin is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.
Cancers (Basel), 2024, 16(21)3606
Adv Healthc Mater, 2023, e2300591.
Theranostics, 2022, 12(12):5451-5469
S4854 Bedaquiline fumarate Bedaquiline fumarate (TMC-207), an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.
Adv Healthc Mater, 2022, e2102117
Microorganisms, 2022, 10(7)1421
S2457 Clindamycin HCl Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
Proc Natl Acad Sci U S A, 2016, 113(50):14408-14413
S1881 Protionamide Protionamide (Prothionamide, 1321-TH) is a drug used in the treatment of tuberculosis.
Mol Imaging Biol, 2021, 10.1007/s11307-021-01689-8
S5199 Oxytetracycline hydrochloride Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
Front Microbiol, 2016, 7:1765
S4490 Tetracycline Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.
PeerJ, 2022, 10:e13719
S5008 Ciprofloxacin (CPX) hydrochloride Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).
Nanomaterials (Basel), 2021, 11(8)1984
S3496 Lefamulin acetate (Xenleta) Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.
J Biol Chem, 2022, 298(5):101909
S6549 PBTZ169 PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1.
Cell Death Dis, 2019, 10(4):319
S4198 Aminothiazole Aminothiazole(2-Aminothiazole,2-Thiazolylamine) can be used as a thyroid inhibitor and it has antibacterial activity.
J Electroanal Chem (Lausanne), 2020, 878:114733
S5047 Methyl α-D-mannopyranoside Methyl α-D-mannopyranoside can be used as an intermediate for chemical sythesis and is a competitor inhibitor of the binding of mannose by Escherichia coli.
mBio, 2022, e0217721
S1162 Pretomanid (PA-824) PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.
S1762 Pyrazinamide Pyrazinamide (Pyrazinoic Acid Amide) is an agent used to treat tuberculosis.
S1791 Bacitracin Zinc Bacitracin(Zinc Bacitracin) is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
S1618 Sulfameter Sulfameter is a long-acting sulfonamide antibacterial.
S1685 Sulfanilamide Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
E2970 Gramicidin Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is an antimicrobial peptide that destroys gram-positive bacteria. It inhibits the growth of bacteria by forming pores and channels in the cell wall, which increase its permeability to monovalent cations.
E3812 Rhamnus Cathartica Extract Rhamnus Cathartica Extract is extracted from Rhamnus cathartica, which has antimicrobial activity.
E3040 Stemonae Extract Stemonae Extract is extracted from Radix Stemonae, has been widely used as an oral anti-tussive agent in traditional Chinese medicine (TCM) for thousands of years with pharmacological effects as anti-tussive, anti-tuberculous, anti-bacterial, anti-fungal and anti-helminthic.
S5105 Proanthocyanidins Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxygen radicals from cells.
Viruses, 2022, 14(2)353
Viruses, 2022, 14(4)764
E3820 Leonurus Japonicus Extract Leonurus Japonicus Extract is extracted from Leonurus japonicus, which has anti-bacterial, anti-cancer, and liver protection activities.
S3295 Taxifolin 7-rhamnoside Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside), a flavonoid isolated from Hypericum japonicum, shows antibacterial activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
E3051 Scutellaria Barbata Extract Scutellaria Barbata Extract is drawed from Scutellaria barbata; Scutellaria barbata nanoparticles (Sb-AgNP) effectively inhibits the biofilm formation and possesses antimicrobial property against skin infection causing microbes.
E3537 Apple cider vinegar Extract Apple Cider Vinegar Extract is extracted from apple cider vinegar, which has antimicrobial activity.
S2596 Clindamycin palmitate HCl Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.
E3046 Patriniae Extract Patriniae Extract is extracted from Patrinia scabiosaefolia or Patrinia villosa, is able to significantly reduce the biofilm formation and dramatically alters the structure of the mature biofilms of Pseudomonas aeruginosa.
E3538 Apple Extract Apple Extract is extracted from Malus, which has an anti-cariogenic effect on S. mutans and aids in the prevention of dental caries.
E3541 Grapefruit Seed Extract Grapefruit Seed Extract is extracted from the seeds of Citrus paradisi Macf., which can be used as an anti-biofilm agent that is effective against S. aureus and E. coli.
E3545 Pu-erh tea Extract Pu-erh tea Extract is the aqueous extract Pu-erh tea, which can alleviate the intestinal inflammation caused by antibiotics, reduce the degree of intestinal lesions, promote the growth of intestinal probiotics and inhibit pathogenic bacteria.
E3548 Chia seed Extract Chia Seed Extract is extracted from the seed of Salvia Hispanica, which contain a highly stable trypsin inhibitor with potential for bacterial management alone or in drug combination therapy with oxacillin.
S2830 Clindamycin Clindamycin inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
S9226 Steviolbioside Steviolbioside (CCRIS-6025), a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
S3703 Phenethyl alcohol Phenethyl alcohol (2-phenylethanol, 2-Phenylethyl alcohol, Benzeneethanol, Phenylethanol) is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
S5186 Cefpiramide Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) is a pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
E3077 Tsaoko Fructus Extract Tsaoko Fructus Extract is extracted from Tsaoko Fructus, which has antibacterial properties.
S0534 PK150 PK150 is an analogue of Sorafenib, which shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively.
E0365 Fucoidan

Fucoidan is an anionic sulfated polysaccharide extracted from marine brown algae with a large range of biological activities, including anti-inflammatory, anti-cancer, anti-viral, anti-oxidation, anticoagulant, antithrombotic, anti-angiogenic and anti-Helicobacter pylori, etc.

Int J Biol Macromol, 2024, 276(Pt 1):133792
S5495 Ceftiofur sodium Ceftiofur sodium is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.
S3499 Monocaprylin Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) exhibits an excellent antibacterial activity against Staphylococcus aureus and Escherichia coli.
E3107 Andrographis Herba Extract Andrographis Herba Extract is obtained from the aerial part of Andrographis paniculata (Burm. F.) Nees, has various activities including antimicrobial and antioxidant, antimalarial, antiangiogenic, anti-inflammatory, anti-diabetic, and in vitro α-glucosidase and α-amylase enzyme inhibitory activities.
S7550 Erythromycin Cyclocarbonate Erythromycin Cyclocarbonate(Davercin), derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.
S4861 Oxindole Oxindole (2-indolone, 2-Oxindole, Indolin-2-one) is an aromatic heterocyclic organic compound which causes sedation, muscle weakness, hypotension, and coma when dosed in excess. Oxindole has anti-cancer, anti-HIV, anti-diabetic, antibacterial and other pharmacological activities.
S3142 Potassium sorbate

Potassium sorbate (Sorbic acid potassium) is a nonpoisonous food preservative isolated from Sorbus aucuparia. Potassium sorbate is an effective inhibitor of most molds and yeasts and some bacteria.

E0010 Hypocrellin A Hypocrellin A (HA) is a perylenequinone isolated from Shiraia bambusicola that shows antiviral, antimicrobial and anticancer activity through mediating multiple signaling pathways. Hypocrellin A also is a selective and potent inhibitor of PKC.
E4983New Omadacycline hydrochloride Omadacycline hydrochloride (PTK0796 hydrochloride) is a first-in-class orally active member of the tetracycline class of antibiotics. Omadacycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride exhibits broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria.
E3611 Camellia japonica Extract Camellia Japonica Extract is extracted from the flowers of Camellia japonica L.. Camellia japonica possesses antimicrobial, antioxidant and antitumoral activity and as being a huge source of polyphenols such as the catechins.
E3612 Cremastra appendiculata Extract Cremastra Appendiculata Extract is extracted from Cremastra appendiculata (Pseudobulbus Cremastrae seu Pleiones), the dried pseudostem of plants of the Orchidaceae family. Cremastra appendiculata has antibacterial, antihypertensive, gout, antitumor, and acetylcholine receptor M3-blocking effects. The extract of cremastra appendiculata can be used to treat Lewis lung cancer, liver cancer, and breast cancer.
S4647 Cefmenoxime hydrochloride Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.
S6867 Glyceryl monocaprate (Monocaprin) Monocaprin (Glyceryl caprate) is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.
E3614 Arnica montana Extract Arnica Montana Extract is extracted from the flowers of Arnica montana L. (Asteraceae). Arnica montana possesses anti-inflammatory, immune-modulatory, anti-sclerotic, analgesic, antifungal, antioxidant, antibacterial, and anticancer bioactivities.
S4602 Acetohydroxamic acid Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
E3621 Crataegi fructus Extract Crataegi Fructus Extract is extracted from the fruits of Crataegi fructus (hawthorn). Crataegi fructus is dry ripe fruit of Crataegus pinnatifida Bge.var. major N. E. Br. or Crataegus pinnatifida Bge.. The extracts and compounds from fructus crataegi show a variety of pharmacological activities, such as a protective effect on patients with heart failure, as well as an increased force of myocardial contraction, improved coronary circulation, antioxidant effects and antimicrobial activities.
E3735 Ficus hirta Vahl Extract Ficus Hirta Vahl Extract is derived from Ficus hirta Vahl. (Wuzhimaotao), which possesses hepatoprotective, antibacterial, and anti-inflammatory bioactivities and improves memory function of AD mice.
S6872 Merbromin Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the KM and decreasing the Kcat of 3CLpro.
E4867New Omadacycline Omadacycline(Amadacycline) is an oral aminomethylcycline antibacterial antibiotic used to treat moderate-to-severe infections, such as community-acquired pneumonia and acute bacterial skin and skin structure infections caused by susceptible organisms. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline has broad-spectrum antibacterial activity and is effective against Gram-positive and Gram-negative aerobic, anaerobic, and atypical bacteria.
E3297 Fenugreek Seed Extract Fenugreek Seed Extract is extracted from the seeds of Trigonella foenum-graecum, which acts as an antibacterial and anticancer agent.
S6584 Amdinocillin Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms.
E3353 Acacia Farnesiana Extract Acacia Farnesiana Extract is extrcated from Acacia Farnesiana, which acts against M. tuberculosis and dysentery bacteria.
E0052 Merafloxacin Merafloxacin (CI-934) is a fluoroquinolone antibacterial thats inhibit -1 frameshifting efficiency of SARS-CoV-2 and other betacoronaviruses.
E3388 Latifolin Extract Ilex kudingcha C.J. Tseng Extract is obtained from Ilex kudingcha C.J. Tseng, which possesses a broad range of pharmacological properties, including antioxidant, hepatoprotectant, antibacterial, antihistaminic, anticancer, neuroprotective and other biological effects.
E3398 Sunflower dish Extract Sunflower dish Extract is extracted from Helianthus, which contains antioxidant, antimicrobial, anti-proliferative, and DNA protective activities.
S0147 KKL-10 KKL-10 is an inhibitor of ribosome rescue that exhibits exceptional broad-spectrum antimicrobial activity against bacteria.
S4983 Sorbic acid Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S3710 Fosfomycin calcium Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
S6031 2,6-Dihydroxybenzoic acid 2,6-Dihydroxybenzoic acid (γ-resorcylic acid, 2-Carboxyresorcinol, 2,6-Resorcylic acid) is a phenolic compound which is known to have poor biological performance such as DPPH scavenging activity and microbial growth inhibition.
S5166 Benzoyleneurea Benzoyleneurea (2,4-Dihydroxyquinazoline, Quinazolinedione, Quinazoline-2,4-diol) scaffold is used in the synthesis of novel protein geranylgeranyltransferase-I inhibitors. Benzoyleneurea possesses anti-bacterial activity.
S6090 JFD01307SC JFD01307SC ([(1,1-dioxidotetrahydrothien-3-yl)amino]acetic acid) shows activity against M.tuberculosis with minimum inhibitory concentrations (MICs) in the range of 8 to 16 µg/ml. JFD01307SC may targets enzymes involved in glutamine biosynthesis.
E3695 Hypericum japonicum Extract Hypericum Japonicum Extract is obtained from the entire herb of Hypericum japonicum, has been widely used for the treatment of bacterial diseases, infectious hepatitis, acute and chronic hepatitis, gastrointestinal disorder, internal hemorrhage and tumour.
E3696 Panax notoginseng Extract Panax notoginseng Extract is is made from the dry roots of Panax notoginseng, which is used to treat inflammation and bleeding, also inhibits Streptococcus pyogenes without affecting oral commensal bacteria.
E4353 Ampicillin Ampicillin (D-(-)-alpha-Aminobenzylpenicillin) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. It exhibits a good minimum inhibitory concentration for Staphylococcus aureus, Escherichia coli, Hemophilus influenzae, and Streptococcus pneumoniae with MICs of 0.6–1 mg/L, 4 mg/L, 0.25 mg/L, and 0.03-0.06 mg/L, respectively.
E3420 Trumpet creeper Extract Trumpet creeper Extract is extracted from Campsis, which has antibacterial and antifungal properties.
E0828 Mitonafide Mitonafide inhibits the activity of Mycobacterium tuberculosis NAD+ dependent DNA ligase A at concentrations of 50 µM. 
E0816 Oritavancin Diphosphate Oritavancin Diphosphate is an orally active glycopeptide antibiotic which is active against Gram-positive bacteria and also has antibacterial activity against multidrug-resistant Streptococcus pneumoniae.
S4105 Closantel Sodium Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S4106 Closantel Closantel (R-31520,nsc 335306) is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
J Fungi (Basel), 2024, 10(2)131
S3712 Tulathromycin A Tulathromycin A is a novel long-acting semi-synthetic tribasic macrocyclic antibiotic of the triamilide group and used for the treatment of pulmonary diseases of swine and cattle.
E3707 Chenopodium ambrosioides Extract Chenopodium Ambrosioides Extract is obtained from Chenopodium ambrosioides Linn. (Chenopodiaceae), which has insecticidal and antimicrobial potency.
E3128 Isatidis Folium Extract Isatidis Folium Extract is obtained from the dry leaves of Isatis indigotica Fort. (family Cruciferae), has been commonly applied in orient countries for centuries as antipyretic, antiviral, anti-inflammatory, anti-influenza, and anti-cancer agents.
E3134 Sphaeranthus Africanus Extract Sphaeranthus Africanus Extract is obtained from Sphaeranthus africanus, of which carvotacetones show antimycobacterial effects.
S0423 GSK2200150A GSK2200150A is identified by high-throughput screening (HTS) campaign that can be used as an anti-tuberculosis (TB) agent (MIC = 0.38 µM).
E3138 Lophatheri Herba Extract Lophatheri Herba Extract is drawed from Herba Lophatheri, which enhances the moisture and oil resistance, antioxidant activity that declines with time, and antimicrobial activity of the chitosan film.
E3723 Lindera aggregata leaves Extract Lindera Aggregata Leaves Extract is derived from the leaves of Lindera aggregate (Sims) Kosterm., which have a wide spectrum of biological effects, including antioxidant, antibacterial, liver and cardiovascular protection.
E2952 2-Chloroacetamide 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase.
S6464 Ftaxilide Ftaxilide is a novel antituberculosis agent.
E3740 Isodon serra Extract Isodon Serra Extract is obtained from Isodon serra (Maxim.) Hara, which processes antitumour, anti-angiogenic, analgesic, antitubercular, anti-inflammatory, antibacterial and anti-ischemic activities.
S0195 Walrycin B Walrycin B is an antibacterial compound and a potent inhibitor of WalR targeting the WalR response regulator.
E3158 Caryophylli Flos Flower Extract Caryophylli Flos Flower Extract is extracted from the flower of Caryophylli Flos, which can be used in treatment for diabetic foot ulcer therapy since it improves diabetic wound healing and exerts antibacterial activity.
S4780 7-Methoxy-4-methylcoumarin 7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label. 7-Methoxy-4-methylcoumarin has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 of 11.76 μg/ml and 13.47 μg/ml, respectively.
S5201 Acetylisovaleryltylosin Tartrate Acetylisovaleryltylosin tartrate (AK105039) is an antimicrobial of the macrolide group with antibacterial activity against Gram-positive bacteria.
E3165 Rabdosiae Rubescentis Herba Extract Rabdosiae Rubescentis Herba Extract is drawed from the dried aerial part of genus Rabdosia rubescens (Hemsl.) Hara of the Lamiaceae family, which possesses several biological activities, such as anti-bacteria, anti-parasites, anti-inflammation, and anticancer.
E4939New Sulfisoxazole acetyl Sulfisoxazole acetyl(N1-Acetylsulfisoxazole, Acetyl sulfafurazole), a sulfisoxazole derivative, is an orally active inhibitor of dihydropteroate synthase. Sulfisoxazole acetyl can be biotransformed primarily to sulfisoxazole, and partly to N(4)-acetyl sulfisoxazole (N4AS). Sulfisoxazole acetyl exhibits antibacterial action.
E3760 Cymbopogon Citratus Extract Cymbopogon Citratus Extract is derived from Cymbopogon citratus DC (Stapf.), which has antimicrobial, antiprotozoal, anti-rheumatic, antitumoural, cardio-protective, anti-inflammatory and gastroprotective properties.
E3771 Millet Extract Millet Extract is derived from millet, which is the primary source of dietary fiber and polyphenols, which offers several health benefits such as antidiabetic, antioxidant, hypocholesterolemic, antimicrobial, and protective effects against diet-related chronic diseases.
E3772 Eyebright Extract Eyebright Extract is extracted from Herba Euphrasiae (Scrophulariaceae), which includes anti-inflammatory, antioxidant, antimicrobial, anticancer, antifungal, antiviral, hypotensive, hapatoprotector, anti-epileptic, and anti-catarrhal activities.
S4544 Urethane Urethane (Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane) is a kind of antineoplastic agent that is also used as a veterinary anesthetic. It is a intermediate in organic synthesis.
DSpace, 2023, Volume 30 Issue 11
E3782 Arctostaphylos Uva Ursi Leaf Extract Arctostaphylos Uva Ursi Leaf Extract is drawed from the Arctostaphylos uva-ursi leaf, which could represent a natural product to counter the virulence of Cutibacterium acnes, representing a new alternative therapeutic option for the treatment of acne vulgaris.
S4425 Rifamycin S Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.
S4436 Pleuromutilin Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
E3791 Surgentodoxa Cuneata Extract Surgentodoxa Cuneata Extract is drawed from Surgentodoxa Cuneata, which has anti-inflammatory, antioxidant, antitumor, antimicrobial, and anti-sepsis activities.
E0515 Cefatrizine Cefatrizine, a broad-spectrum, semisynthetic, first-generation cephalosporin with antibacterial activity, binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
S7739 Telacebec Telacebec is a novel antituberculosis drug that targets Mycobacterium tuberculosis cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. Telacebec (Q203, IAP6) is active against Mycobacterium tuberculosis H37Rv with MIC50 of 2.7 nM in culture broth medium.
S4404 Pasiniazid Pasiniazid(Paraniazide,Pasiniazide) is a composition of isoniazid and 4-aminosalicylic acid, used to treat tuberculosis patients.
E3510 Costustoot Extract Costustoot Extract is extracted from the roots of costus, which has antibacterial properties and serves an inhibitory role in the regeneration of gut bacteria.
E3802 Inula Cappa Extract Inula Cappa Extract is drawed from Inula Cappa, which has many biological activities and exerts anti-inflammatory, analgesic, antibacterial, antitumor, antioxidant, and immunomodulatory effects.
E3514 Burdock root Extract Burdock Root Extract is extracted from the roots of Arctium, which exhibits antibiofilm activity.
E3806 Allium Cepa Extract Allium Cepa Extract is drawed from Allium cepa Linnaeus, which has hypoglycaemic, anti-diabetic, hypolipidemic and antimicrobial functions.
E3810 Bauhinia Variegata Extract Bauhinia Variegata Extract is drawed from Bauhinia variegata L., which has antibacterial, antioxidant, anti-inflammatory and anticarcinogenic effects.
E3520 Goose Grass Extract Goose Grass Extract is isolated from Eleusine indica, which displays antioxidant, antimicrobial and anticancer activities.
E4983New Omadacycline hydrochloride Omadacycline hydrochloride (PTK0796 hydrochloride) is a first-in-class orally active member of the tetracycline class of antibiotics. Omadacycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride exhibits broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria.
E4867New Omadacycline Omadacycline(Amadacycline) is an oral aminomethylcycline antibacterial antibiotic used to treat moderate-to-severe infections, such as community-acquired pneumonia and acute bacterial skin and skin structure infections caused by susceptible organisms. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline has broad-spectrum antibacterial activity and is effective against Gram-positive and Gram-negative aerobic, anaerobic, and atypical bacteria.
E6017New Ornidazole (Levo-) Ornidazole (Levo-) (Levornidazole, (S)-Ornidazole), the levo-isomer of ornidazole, is a third-generation nitroimidazole derivative. It exhibits antiprotozoal and antibacterial properties against anaerobic bacteria.
E4939New Sulfisoxazole acetyl Sulfisoxazole acetyl(N1-Acetylsulfisoxazole, Acetyl sulfafurazole), a sulfisoxazole derivative, is an orally active inhibitor of dihydropteroate synthase. Sulfisoxazole acetyl can be biotransformed primarily to sulfisoxazole, and partly to N(4)-acetyl sulfisoxazole (N4AS). Sulfisoxazole acetyl exhibits antibacterial action.
E4954New Demeclocycline Demeclocycline(Demethylchlortetracycline (DMCT), Ledermycin) is a bacteriostatic antibiotic from the tetracycline class, that induces diuresis and can cause nephrogenic diabetes insipidus. It also manages the syndrome of inappropriate antidiuretic hormone secretion (SIADH) by restoring normal plasma sodium levels and permitting unrestricted water intake.

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