Home Proteases MMP activator Ginkgolide C For research use only.

Ginkgolide C

Synonyms: BN-52022

Ginkgolide C (BN-52022), isolated from Ginkgo biloba leaves, is a flavone reported to have multiple biological functions, from decreased platelet aggregation to ameliorating Alzheimer disease. Ginkgolide C can activate the AMPK signaling pathway and also promote the conversion of pro-MMP-9 to its active form MMP-9.

Ginkgolide C Chemical Structure

Ginkgolide C Chemical Structure

CAS No. 15291-76-6

Purity & Quality Control

Batch: S378101 DMSO]88 mg/mL]false]]]false]]]false Purity: 98%
98

Ginkgolide C Related Products

Signaling Pathway

MMP Signaling Pathways

MMP Signaling Pathway

Biological Activity

Description Ginkgolide C (BN-52022), isolated from Ginkgo biloba leaves, is a flavone reported to have multiple biological functions, from decreased platelet aggregation to ameliorating Alzheimer disease. Ginkgolide C can activate the AMPK signaling pathway and also promote the conversion of pro-MMP-9 to its active form MMP-9.
Targets
MMP-9 [3]
In vitro
In vitro

Ginkgolide C significantly suppresses lipid accumulation in differentiated adipocytes. It also decreases adipogenesis-related transcription factor expression, including peroxisome proliferator-activated receptor and CCAAT/enhancer-binding protein. Furthermore, ginkgolide C enhances adipose triglyceride lipase and hormone-sensitive lipase production for lipolysis and increases phosphorylation of AMP-activated protein kinase (AMPK), resulting in decreased activity of acetyl-CoA carboxylase for fatty acid synthesis[1].

Chemical Information & Solubility

Molecular Weight 440.40 Formula

C20H24O11
CAS No. 15291-76-6 SDF Download Ginkgolide C SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 88 mg/mL ( (199.81 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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