Home Proteases Serine Protease inhibitor Gabexate Mesylate For research use only.

Gabexate Mesylate

Synonyms: FOY

Gabexate Mesylate(FOY) is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation.

Gabexate Mesylate Chemical Structure

Gabexate Mesylate Chemical Structure

CAS No. 56974-61-9

Purity & Quality Control

Batch: S210101 DMSO]83 mg/mL]false]Ethanol]83 mg/mL]false]Water]12 mg/mL]false Purity: 99.61%
99.61

Gabexate Mesylate Related Products

Biological Activity

Description Gabexate Mesylate(FOY) is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation.
Targets
serine protease [1]
0.19 μM
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04451083 Completed
Healthy Volunteers
Ono Pharmaceutical Co. Ltd
 July 1 2020 Phase 1
NCT02693093 Completed
Chronic Pancreatitis
Kangen Pharmaceuticals Inc
 February 24 2016 Phase 1|Phase 2

Chemical Information & Solubility

Molecular Weight 417.48 Formula

C16H23N3O4.CH4O3S
CAS No. 56974-61-9 SDF Download Gabexate Mesylate SDF
Smiles CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 83 mg/mL ( (198.81 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 83 mg/mL

Water : 12 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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