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Technical Data
| Formula | C16H23N3O4.CH4O3S |
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| Molecular Weight | 417.48 | CAS No. | 56974-61-9 | |
| Solubility (25°C)* | In vitro | DMSO | 83 mg/mL (198.81 mM) | |
| Ethanol | 83 mg/mL (198.81 mM) | |||
| Water | 12 mg/mL (28.74 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Gabexate Mesylate(FOY) is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation. | ||
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Protocol (from reference)
Customer Product Validation
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Data from [Data independently produced by , , Medical Oncology, 2016, 33:53.]
Selleck's Gabexate Mesylate has been cited by 5 publications
| Discovery of diminazene as a dual inhibitor of SARS-CoV-2 human host proteases TMPRSS2 and furin using cell-based assays [ Curr Res Chem Biol, 2022, 2:100023] | PubMed: 35815069 |
| LSD1 Activates PI3K/AKT Signaling Through Regulating p85 Expression in Prostate Cancer Cells. [ Front Oncol, 2019, 0.87569444444] | PubMed: 31428587 |
| Region-specific proteolysis differentially modulates type 2 and type 3 inositol 1,4,5-trisphosphate receptor activity in models of acute pancreatitis [ J Biol Chem, 2018, 293(34):13112-13124] | PubMed: 29970616 |
| Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity. [ Invest Ophthalmol Vis Sci, 2016, 57(14):6461-6473] | PubMed: 27893888 |
| Inhibition of glioblastoma cell proliferation, migration and invasion by the proteasome antagonist carfilzomib. [Areeb Z, et al. Med Oncol, 2016, 33(5):53] | PubMed: 27098175 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.