Home Microbiology Bacterial inhibitor Fosfomycin calcium For research use only.

Fosfomycin calcium

Synonyms: phosphomycin calcium, phosphonomycin calcium

Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.

Fosfomycin calcium Chemical Structure

Fosfomycin calcium Chemical Structure

CAS No. 26472-47-9

Purity & Quality Control

Batch: S371001 5%TFA]3.06 mg/mL]false]DMSO]0.1 mg/mL]false]Water]Insoluble]false Purity: 99.15%
99.15

Fosfomycin calcium Related Products

Biological Activity

Description Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
Targets
MurA [1]

Chemical Information & Solubility

Molecular Weight 176.12 Formula

C3H5O4P.Ca
CAS No. 26472-47-9 SDF Download Fosfomycin calcium SDF
Smiles CC1C(O1)P(=O)([O-])[O-].[Ca+2]
Storage (From the date of receipt)

In vitro
Batch:

5%TFA : 3.06 mg/mL

DMSO : 0.1 mg/mL ( (0.56 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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