Home Neuronal Signaling Dopamine Receptor agonist Fenoldopam mesylate For research use only.

Fenoldopam mesylate

Synonyms: SKF 82526 (mesylate), Fenoldopam methanesulfonate, Corlopam mesylate

Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.

Fenoldopam mesylate Chemical Structure

Fenoldopam mesylate Chemical Structure

CAS No. 67227-57-0

Purity & Quality Control

Fenoldopam mesylate Related Products

Signaling Pathway

Dopamine Receptor Signaling Pathways

Dopamine Receptor Signaling Pathway

Biological Activity

Description Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
Targets
D1 receptor [1]
In Vivo
In vivo Fenoldopam (20 μg/kg) induced a marked decrease in systolic blood pressure, diastolic blood pressure and heart rate[1].
Animal Research Animal Models Conscious sinoaortic denervated dogs
Dosages 0.9% NaCl
Administration i.v.

Chemical Information & Solubility

Molecular Weight 401.86 Formula

C16H16ClNO3.CH4O3S
CAS No. 67227-57-0 SDF Download Fenoldopam mesylate SDF
Smiles CS(=O)(=O)O.C1CNCC(C2=CC(=C(C(=C21)Cl)O)O)C3=CC=C(C=C3)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 80 mg/mL ( (199.07 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
Batch:

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

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