Fenoldopam mesylate

Catalog No.S4618 Batch:S461801

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Technical Data

Formula

C16H16ClNO3.CH4O3S

Molecular Weight 401.86 CAS No. 67227-57-0
Solubility (25°C)* In vitro DMSO 80 mg/mL (199.07 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
Targets
D1 receptor [1]
In vivo Fenoldopam (20 μg/kg) induced a marked decrease in systolic blood pressure, diastolic blood pressure and heart rate[1].

Protocol (from reference)

Animal Study:

[1]

  • Animal Models

    Conscious sinoaortic denervated dogs

  • Dosages

    0.9% NaCl

  • Administration

    i.v.

Selleck's Fenoldopam mesylate has been cited by 2 publications

Propafenone facilitates mitochondrial-associated ferroptosis and synergizes with immunotherapy in melanoma [ J Immunother Cancer, 2024, 12(11)e009805] PubMed: 39581704
The Food and Drug Administration-approved antipsychotic drug trifluoperazine, a calmodulin antagonist, inhibits viral replication through PERK-eIF2α axis [ Front Microbiol, 2022, 13:979904] PubMed: 36386620

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.