Acetohydroxamic acid

Synonyms: N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid|oxime, AHA

Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.

Acetohydroxamic acid Chemical Structure

Acetohydroxamic acid Chemical Structure

CAS No. 546-88-3

Purity & Quality Control

Acetohydroxamic acid Related Products

Biological Activity

Description Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
Targets
Urease [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06372041 Not yet recruiting
Cerebral Palsy
IRCCS Eugenio Medea|IRCCS National Neurological Institute C. Mondino Foundation|Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
April 15 2024 Not Applicable
NCT06372028 Not yet recruiting
Cerebral Palsy
IRCCS Eugenio Medea|IRCCS National Neurological Institute C. Mondino Foundation|Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
April 15 2024 Not Applicable
NCT05828849 Not yet recruiting
Cardiovascular Disease|Alcohol Use Disorder|HIV Risk|Substance Use Disorders
NYU Langone Health|National Institute on Alcohol Abuse and Alcoholism (NIAAA)
April 15 2024 Not Applicable
NCT06311461 Recruiting
Angina Stable
University of California Los Angeles|University of Illinois at Chicago
April 1 2024 Not Applicable

Chemical Information & Solubility

Molecular Weight 75.07 Formula

C2H5NO2

CAS No. 546-88-3 SDF Download Acetohydroxamic acid SDF
Smiles CC(=O)NO
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 15 mg/mL ( (199.81 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 15 mg/mL

Ethanol : 15 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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