Home Metabolism PPAR agonist 2,4-Thiazolidinedione For research use only.

2,4-Thiazolidinedione

Synonyms: Thiazolidinedione

2,4-Thiazolidinedione (Thiazolidinedione), an insulin sensitizer, is a specific agonist of peroxisome proliferator-activated receptor (PPAR)γ. Thiazolidinedione treatment corrects impaired muscle insulin action in vivo.

2,4-Thiazolidinedione Chemical Structure

2,4-Thiazolidinedione Chemical Structure

CAS No. 2295-31-0

Purity & Quality Control

Batch: E177501 DMSO]23 mg/mL]false]Water]23 mg/mL]false]Ethanol]23 mg/mL]false Purity: 99.56%
99.56

2,4-Thiazolidinedione Related Products

Signaling Pathway

PPAR Signaling Pathways

PPAR Signaling Pathway

Biological Activity

Description 2,4-Thiazolidinedione (Thiazolidinedione), an insulin sensitizer, is a specific agonist of peroxisome proliferator-activated receptor (PPAR)γ. Thiazolidinedione treatment corrects impaired muscle insulin action in vivo.
Targets
PPARγ [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03791580 Unknown status
Fall|Congestive Heart Failure|Chronic Kidney Failure|Adverse Drug Event
RAND|Northwestern University|University of California Los Angeles|University of Southern California|University of Pittsburgh|National Institute on Aging (NIA)
 February 11 2019 Not Applicable
NCT00432809 Completed
Diabetes Mellitus Type 2|Obesity
The Cleveland Clinic|Ethicon Endo-Surgery|LifeScan
 February 2007 Not Applicable

Chemical Information & Solubility

Molecular Weight 117.13 Formula

C3H3NO2S
CAS No. 2295-31-0 SDF Download 2,4-Thiazolidinedione SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 23 mg/mL ( (196.36 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 23 mg/mL

Ethanol : 23 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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