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Retinoid Receptor
Retinoid Receptor Products
- All (18)
- Retinoid Receptor Inhibitor (1)
- Retinoid Receptor Antagonists (2)
- Retinoid Receptor Agonists (15)
- New Retinoid Receptor Products
| Catalog No. | Product Name | Information | Product Use Citations | Product Validations |
|---|---|---|---|---|
| S1653 | Retinoic acid (Tretinoin) | Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. Tretinoin (NSC 122758) can be used to induce animal models of osteoporosis. |
|
|
| S2098 | Bexarotene | Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma. |
|
|
| S4627 | TTNPB | TTNPB is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively. | ||
| S2933 | AM580 | AM580 is a retinoic acid receptor agonist with Kd values of 8 nM, 131 nM and 450 nM for RARα, RARβ and RARγ. | ||
| S1276 | Adapalene | Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne. | ||
| S1368 | Acitretin | Acitretin (Etretin, RO 10-1670) is a second generation retinoid used for psoriasis. |
|
|
| S1569 | Tazarotene | Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin. | ||
| S4260 | Tamibarotene | Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ. | ||
| S2833 | UVI 3003 | UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR) with IC50 of 0.24 μM against human RXR. | ||
| S5233 | Fenretinide | Fenretinide is a synthetic derivative of retinoic acid that has a broad-spectrum of cytotoxic activity against primary tumor cells, cell lines, and/or xenografts of various cancers (including neuroblastoma). Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) is a synthetic derivative of retinoic acid, fenretinide can bind to retinoic acid receptor (RAR) and retinoid X receptor (RXR) at concentrations necessary to induce cell death. | ||
| E2813 | SR 11237 | SR 11237, a retinoid X receptor (RXR)-specific agonist, can cause RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element. | ||
| S4699 | Etretinate | Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells. | ||
| E1627New | BMS493 | BMS493 is an inverse agonist of pan retinoic acid receptor (RAR). It increases nuclear corepressor interaction with RARs and can be used as an inhibitor for the dietary and pharmacologic manipulation of retinoic acid (RA) activity in vivo and in vitro. | ||
| E1445 | Palovarotene | Palovarotene (R 667; Ro 3300074) is a nuclear retinoic acid receptor γ (RAR-γ) agonist. It reduces heterotopic ossification (HO) in cultures and in murine and rat fibrodysplasia ossificans progressiva (FOP) models. | ||
| S6605 | AR7 | AR7 is a retinoic acid receptor α (RARα) antagonist. | ||
| S6132 | All trans-Retinal | All trans-Retinal (Retinaldehyde, Vitamin A aldehyde, Retinene), a component of the retinoid cycle, is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both RAR and RXR. All trans-retinal ias a potent photosensitizer. | ||
| S2520 | CD437(AHPN) | CD437(AHPN), a synthetic retinoid, is a selective Retinoic acid Receptor γ ( RARγ) agonist. It exhibits an antiproliferative effect and induces apoptosis via activation of AP-1 in vitro. | ||
| E1468 | MSU-42011 | MSU-42011 is an orally active agonist of retinoid X receptor (RXR). MSU-42011 inhibits the expression of iNOS and p-ERK protein. It exhibits immunomodulatory and antitumor activity. MSU-42011 can be used for cancer research. | ||
| S5233 | Fenretinide | Fenretinide is a synthetic derivative of retinoic acid that has a broad-spectrum of cytotoxic activity against primary tumor cells, cell lines, and/or xenografts of various cancers (including neuroblastoma). Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) is a synthetic derivative of retinoic acid, fenretinide can bind to retinoic acid receptor (RAR) and retinoid X receptor (RXR) at concentrations necessary to induce cell death. | ||
| S2833 | UVI 3003 | UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR) with IC50 of 0.24 μM against human RXR. | ||
| S6605 | AR7 | AR7 is a retinoic acid receptor α (RARα) antagonist. | ||
| S1653 | Retinoic acid (Tretinoin) | Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. Tretinoin (NSC 122758) can be used to induce animal models of osteoporosis. |
|
|
| S2098 | Bexarotene | Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma. |
|
|
| S4627 | TTNPB | TTNPB is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively. | ||
| S2933 | AM580 | AM580 is a retinoic acid receptor agonist with Kd values of 8 nM, 131 nM and 450 nM for RARα, RARβ and RARγ. | ||
| S1276 | Adapalene | Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne. | ||
| S1368 | Acitretin | Acitretin (Etretin, RO 10-1670) is a second generation retinoid used for psoriasis. |
|
|
| S1569 | Tazarotene | Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin. | ||
| S4260 | Tamibarotene | Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ. | ||
| E2813 | SR 11237 | SR 11237, a retinoid X receptor (RXR)-specific agonist, can cause RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element. | ||
| S4699 | Etretinate | Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells. | ||
| E1627New | BMS493 | BMS493 is an inverse agonist of pan retinoic acid receptor (RAR). It increases nuclear corepressor interaction with RARs and can be used as an inhibitor for the dietary and pharmacologic manipulation of retinoic acid (RA) activity in vivo and in vitro. | ||
| E1445 | Palovarotene | Palovarotene (R 667; Ro 3300074) is a nuclear retinoic acid receptor γ (RAR-γ) agonist. It reduces heterotopic ossification (HO) in cultures and in murine and rat fibrodysplasia ossificans progressiva (FOP) models. | ||
| S6132 | All trans-Retinal | All trans-Retinal (Retinaldehyde, Vitamin A aldehyde, Retinene), a component of the retinoid cycle, is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both RAR and RXR. All trans-retinal ias a potent photosensitizer. | ||
| S2520 | CD437(AHPN) | CD437(AHPN), a synthetic retinoid, is a selective Retinoic acid Receptor γ ( RARγ) agonist. It exhibits an antiproliferative effect and induces apoptosis via activation of AP-1 in vitro. | ||
| E1468 | MSU-42011 | MSU-42011 is an orally active agonist of retinoid X receptor (RXR). MSU-42011 inhibits the expression of iNOS and p-ERK protein. It exhibits immunomodulatory and antitumor activity. MSU-42011 can be used for cancer research. | ||
| E1627New | BMS493 | BMS493 is an inverse agonist of pan retinoic acid receptor (RAR). It increases nuclear corepressor interaction with RARs and can be used as an inhibitor for the dietary and pharmacologic manipulation of retinoic acid (RA) activity in vivo and in vitro. |
Choose Selective Retinoid Receptor Inhibitors
Tags: Retinoid Receptor inhibitor|Retinoid Receptor agonist|Retinoid Receptor activator|Retinoid Receptor inducer|Retinoid Receptor antagonist|Retinoid Receptor signaling pathway|Retinoid Receptor assay kit
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