Volociximab (Anti-Integrin a5b1 (ITGA5 & ITGB1))

Synonyms: Anti-alpha5beta1 integrin monoclonal antibody

Catalog No.A3106 Purity:99%

Volociximab (Anti-Integrin a5b1 (ITGA5 & ITGB1)) is a monoclonal antibody targeting Integrin a5b1 (ITGA5 & ITGB1). It can be used in treatment of solid tumors, renal cell carcinoma, melanoma, pancreatic cancer, lung cancer, and ovarian cancer. MW :145.52 KD.

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 9.96mg/ml Endotoxin Level: ＜1EU/mg

Choose Selective Integrin Inhibitors

Name	Citation	Integrin
Cilengitide trifluoroacetate	66	+++
A-205804	5	++
Cyclo(RGDyK)	13	++
SB273005	25	++++
RGD (Arg-Gly-Asp) Peptides	✔
ATN-161	✔
Cyclo(-RGDfK) TFA	✔

Expand to Check More

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Volociximab (Anti-Integrin a5b1 (ITGA5 & ITGB1)) is a monoclonal antibody targeting Integrin a5b1 (ITGA5 & ITGB1). It can be used in treatment of solid tumors, renal cell carcinoma, melanoma, pancreatic cancer, lung cancer, and ovarian cancer. MW :145.52 KD.

References
[1] Ng CM, et al. Cancer Chemother Pharmacol. 2010 Jan;65(2):207-17

References

[1] Ng CM, et al. Cancer Chemother Pharmacol. 2010 Jan;65(2):207-17

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	558480-40-3
Isotype	Human IgG4SP
Source	CHO
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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