Home Cytoskeletal Signaling Integrin antagonist GLPG0187 For research use only.

GLPG0187

GLPG0187 is a broad-spectrum antagonist of integrin receptor. It inhibits αvβ1-integrin with an IC50 value of 1.3 nM. GLPG0187 also inhibits migrasome biogenesis without cytotoxicity. GLPG0187 exhibits potent antitumor activity.

GLPG0187 Chemical Structure

GLPG0187 Chemical Structure

CAS No. 1320346-97-1

Purity & Quality Control

Batch: E461501 DMSO]100 mg/mL]false]Ethanol]3 mg/mL]false]Water]2 mg/mL]false Purity: 98.52%
98.52

GLPG0187 Related Products

Signaling Pathway

Integrin Signaling Pathways

Integrin Signaling Pathway

Biological Activity

Description GLPG0187 is a broad-spectrum antagonist of integrin receptor. It inhibits αvβ1-integrin with an IC50 value of 1.3 nM. GLPG0187 also inhibits migrasome biogenesis without cytotoxicity. GLPG0187 exhibits potent antitumor activity.

Chemical Information & Solubility

Molecular Weight 595.72 Formula

C29H37N7O5S
CAS No. 1320346-97-1 SDF Download GLPG0187 SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (167.86 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 3 mg/mL

Water : 2 mg/mL


Molecular Weight Calculator

In vivo
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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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