Vobarilizumab (Anti-IL-6Ra / CD126)

Synonyms: ALX-0061

Vobarilizumab (Anti-IL-6Ra / CD126) is a monoclonal antibody targeting IL-6R. It can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis. MW :78.2 KD.

Vobarilizumab (Anti-IL-6Ra / CD126)

Purity & Quality Control

Choose Selective Interleukins Inhibitors

Name Citation IL-6 IL-1 IL-8 IL-12 IL-10 IL-13 IL-2 Others
SKF-86002 0
JTE-607 Dihydrochloride 0 TNF-alpha
A-740003 2 rat P2X7 receptor,human P2X7 receptor
Apilimod mesylate 3 PIKfyve
MD2-TLR4-IN-1 0 TLR4,TNF-α
Danirixin (GSK1325756) 2 CXCR2
Resatorvid (TAK-242) 50 TLR4,NO,TNF-α
Apilimod 14 PIKfyve
LMT-28
Atractylodin NAAA
Triolein ROS,MMP-1
Ac-YVAD-cmk
Diethyl phosphate
RCM-1 STAT6,FOXM1,β-catenin
Stylopine COX-2,TNF-α,NO
Myrislignan NF-κB,COX-2,iNOS
NE 52-QQ57 iNOS,TNF-α,PGE2
PKR-IN-C16 PKR
Falcarindiol STAT,ERK,JNK
Gardenoside P2X7 Receptor,P2X3 receptor,NF-κB
T-5224 c-Jun,c-Fos/AP-1,Adamts-5
IQ 3 TNF-α,JNK3,JNK1
Isuzinaxib (APX-115 free base) TNFα,MCP-1/CCL2,NOX2
AUDA p38,Smad3,TGF-β
SAR-20347 IFN-α,TYK2,JAK1
SU 5201
Madecassic acid TNF-α,COX-2,iNOS
Homoplantaginin NF-κB,IKKβ,TNF-α
2',5'-Dihydroxyacetophenone NF-κB,ERK1/2,iNOS
Forsythoside B NF-κB,TNF-alpha,IκB
Mulberroside A NF-κB,Caspase-1,NALP3
Chelidonic acid glutamate decarboxylase,Caspase-1,NF-κB
4-Methylesculetin MPO
Muscone TNF-α,NLRP3 inflammasome,NF-κB
Ossirene (AS101)
Methylthiouracil ERK1/2,NF-κB,TNF-α
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Vobarilizumab (Anti-IL-6Ra / CD126) is a monoclonal antibody targeting IL-6R. It can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis. MW :78.2 KD.

Product Details

CAS No. 1628814-88-9
Molecular Weight 78.2
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac,pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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