Home Immunology & Inflammation NOS inhibitor - TNF-alpha inhibitor - Interleukins inhibitor - JNK inhibitor - ERK inhibitor - STAT inhibitor Falcarindiol For research use only.

Falcarindiol

Synonyms: FAD, (3R,8S)-Falcarindiol, FaDOH

Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) is a natural polyacetylene compound found rich in many plants of the Umbelliferae family. Falcarindiol suppresses LPS-stimulated expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), and interleukin-1 beta (IL-1β). Falcarindiol attenuates the LPS-induced activation of JNK, ERK, STAT1, and STAT3 signaling molecules.

Falcarindiol Chemical Structure

Falcarindiol Chemical Structure

CAS No. 225110-25-8

Purity & Quality Control

Falcarindiol Related Products

Biological Activity

Description Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) is a natural polyacetylene compound found rich in many plants of the Umbelliferae family. Falcarindiol suppresses LPS-stimulated expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), and interleukin-1 beta (IL-1β). Falcarindiol attenuates the LPS-induced activation of JNK, ERK, STAT1, and STAT3 signaling molecules.
Targets
iNOS [1] TNFα [1] IL-6 [1] IL-1β [1] JNK [1] Click to View More Targets
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06312410 Not yet recruiting
Child|Parents|Mental Disorder|Child of Impaired Parents|Preventive Health Services
Mental Health Services in the Capital Region Denmark|Aalborg Psychiatric Hospital|TrygFonden Denmark|Novo Nordisk A/S|Lundbeck Foundation|Liljeborgfonden|Ebbefos Fonden|KV Fonden
 March 18 2024 Not Applicable
NCT06159894 Not yet recruiting
HIV Infections
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
 December 2023 Not Applicable

Chemical Information & Solubility

Molecular Weight 260.37 Formula

C17H24O2
CAS No. 225110-25-8 SDF --
Smiles CCCCCCCC=CC(C#CC#CC(C=C)O)O
Storage (From the date of receipt) 2 years -20°C liquid

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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